|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: A research study显示文摘AIM: To investigate plasma microRNA (miRNA) profiles indicative of hepatotoxicity in the setting of lethal acetaminophen (APAP) toxicity in mice. METHODS: Using plasma from APAP poisoned mice, either lethally (500 mg/kg) or sublethally (150 mg/kg) dosed, we screened commercially available murine microRNA libraries (SABiosciences, Qiagen Sciences, MD) to evaluate for unique miRNA profiles between these two dosing parameters. RESULTS: We distinguished numerous, unique plasma miRNAs both up- and downregulated in lethally compared to sublethally dosed mice. Of note, many of the greatest up- and downregulated miRNAs, namely 574-5p, 466g, 466f-3p, 375, 29c, and 148a, have been shown to be associated with asthma in prior studies. Interestingly, a relationship between APAP and asthma has been previously well described in the literature, with an as yet unknown mechanism of pathology. There was a statistically significant increase in alanine aminotransferase levels in the lethal compared to sublethal APAP dosing groups at the 12 h time point (P < 0.001). There was 90% mortality in the lethally compared to sublethally dosed mice at the 48 h time point (P = 0.011). CONCLUSION: We identified unique plasma miRNAs both up- and downregulated in APAP poisoning which are correlated to asthma development. | Jeanine Ward Shashi Bala Jan Petrasek Gyongyi Szabo | 2012 | World Journal of Gastroenterology2012，18，22： | 6 |
| 2 | IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice显示文摘 | Petrasek Jan Bala Shashi Csak Timea Lippai Dora Kodys Karen Menashy Victoria Barrieau Matthew Min So-Yun Kurt-Jones Evelyn A Szabo Gyongyi | 2012 | EN2012，，10： | 4 |
| 3 | STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease显示文摘 | Jan Petrasek Arvin Iracheta-Vellve Timea Csak Abhishek Satishchandran Karen Kodys Evelyn A. Kurt-Jones Katherine A. Fitzgerald Gyongyi Szabo | 2013 | Proceedings of the National Academy of Sciences2013，，41： | 2 |
| 4 | Metals removals and partitioning in conventional wastewater treatment plant显示文摘 | PETRASEK A C IRWIN J R KUGELMAN I J | 1993 | Journal WPCF1993，55，9： | 1 |
| 5 | Relation of the thickness of the intima and mediaof the common carotid artery,atherosclerotic plaque in the carotids and manifestations of atherosclerosis in the vessels of the lower extremity in comparison to coronary atherosclerosis显示文摘 | Holaj R Spacil J Petrasek J | 1998 | Cas Lek Cesk1998，137，23： | 1 |
| 6 | Relation of the thickness of the intima and media of the common carotid artery, atherosclerotic plaque in the carotids and manifestations of atherosclerosis in the vessels of the lower extremity in comparison to coronary atherosclerosis 显示文摘 | Holaj R Spacil J Petrasek J | 1998 | Cas Lek Cesk1998，137，： | 1 |
| 7 | The Unfolding Web of Innate Immune Dysregulation in Alcoholic Liver Injury显示文摘 | Szabo G Mandrekar P Petrasek J | | 0，，： | 1 |
| 8 | Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells 显示文摘 | Petrasek J Dolganiuc A Csak T | 2011 | Hepatology2011，53，2： | 1 |
| 9 | Do Transparent Firms Pay out More Cash to Shareholders Evidence from International Cross-Listings显示文摘 | Lubomir Petrasek | 2012 | Financial Management· Fall2012，，： | 1 |
| 10 | Relation of the thickness of the intima and media of the common carotid artery,atherosclerotic plaque in the carotids and manifestations of atherosclerosis in the vessels of the lower extremity in comparison to coronary atherosclerosis显示文摘 | Holaj R Spacil J Petrasek J | 1998 | Cas Lek Cesk1998，137，23： | 1 |
| 11 | Ameli Fm Chylous ascites 显示文摘 | Petrasek AJ | 1996 | Can J Surg1996，39，6： | 1 |
| 12 | IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice显示文摘 | Petrasek J Bala S Csak T | 2012 | J Clin Invest2012，122，10： | 1 |
| 13 | Intimamedia thickness of the common cartiod artery is the significant predictor of angiogiphically proven coronary artery disease显示文摘 | Holajr Spacil J Petrasek J | 2003 | Can J Cardiol2003，19，6： | 1 |
| 14 | Endovascular stent grafts for acute blunt aortic injury 显示文摘 | Dunham MB Zygun D Petrasek P | 2004 | J Trauma2004，56，： | 1 |
| 15 | The unfolding web of innate immune dysregulation in alcoholic liver injury显示文摘 | Szabo G Mandrekar P Petrasek J | 2011 | Alcohol Clin Exp Res2011，35，5： | 1 |
| 16 | Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic,drug-induced,and inflammatory liver diseases显示文摘 | Bala S Petrasek J Mundkur S | 2012 | Hepatology2012，56，5： | 1 |
| 17 | Relation of the thickness of the intima and media of the common carotid artery,atherosclerotic plaque in the carotids and manifestations of atherosclerosis in the vessels of the lower extremity in comparison to coronary atherosclerosis 显示文摘 | Holaj R Spacil J Petrasek J | 1998 | Cas Lek Cesk1998，137，23： | 1 |
| 18 | Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice显示文摘 | Petrasek J Dolganiuc A Csak T | 2011 | Gastroenterology2011，140，2： | 1 |
| 19 | PIN proteins perform a rate limiting function in cellular auxin efflux显示文摘 | PETRASEK J MRAVEC J BOUCHARD R | 2006 | Science2006，312，： | 1 |
| 20 | IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice显示文摘 | Petrasek J Bala S Csak T | | 0，，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员