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| 1 | Novel hMSH2,hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer显示文摘 | Chaksangchaichot P Punyarit P Petmitr S | 2007 | J Cancer Res Clin Oncol2007，133，1： | 1 |
| 2 | Polymorphism of glutathione S -transferase Omega gene and risk of cancer显示文摘 | Sujan Babu Marahatta Phaibul Punyarit Vajarabhongsa Bhudisawasdi Anucha Paupairoj Sopit Wongkham Songsak Petmitr | 2005 | Cancer Letters2005，，2： | 1 |
| 3 | Stage specificity of Plasmodium falciparum telomerase and its inhibition by berberine显示文摘 | Sdw hijareon N Petmitr S Mu rangllra A | 2002 | J Parasitol Int2002，51，1： | 1 |
| 4 | The genetic as- sociation between alpha-2-macroglobulin (A2M) gene deletion polymorphism and low serum A2M concentration in overweight/ obese Thais显示文摘 | Rugsarash W Tungtrongchitr R Petmitr S | 2006 | Nutr Neurosci2006，9，12： | 1 |
| 5 | Differential detection of Entamoeba histolytica, Entamoeba dispar, and Entamoebamoshkovskii by a single-round PCR assay显示文摘 | Hamzah Z Petmitr S Mungthin M | 2006 | J Clin Microbiol2006，44，9： | 1 |
| 6 | Polymorphism of glutathione S -transferase Omega gene: association with risk of childhood acute lymphoblastic leukemia显示文摘 | W. Pongstaporn S. Pakakasama S. Sanguansin S. Hongeng Songsak Petmitr | 2009 | Journal of Cancer Research and Clinical Oncology2009，，5： | 1 |
| 7 | Gametocytocidalactivity of pyronaridine and DNA topoisomerase II inhibitors againstmultidrug-resistant Plasmodium falciparum in vitro显示文摘 | Petmitr P Pongvilairat G Auparakkitanon S | 2000 | Parasitol Int2000，48，4： | 1 |
| 8 | Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer 显示文摘 | Chaksangchaichot P Punyarit P Petmitr S | 2007 | Cancer Res Clin 0ncol2007，133，1： | 1 |
| 9 | Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer显示文摘 | Chaksanqchaichot P Punyarit P Petmitr S | 2007 | J Cancer Res Clin Oncol2007，133，1： | 1 |
| 10 | Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer显示文摘 | Petmitr S etal | 2007 | J Cancer Res Clin Oncol2007，133，1： | 1 |
| 11 | Stage specificity of P1asmodium falciparum telomerase and its inhibition by berberine 显示文摘 | Sriwilaijareon N Petmitr S Mutirangura A | 2002 | Parasitol Int2002，51，1： | 1 |
| 12 | Differential detection of Entamoeba histolytica, Entamoeba dispar, and En- tamoeba moshkovskii by a single -round PCR assay 显示文摘 | HAMZAH Z PETMITR S MUNGTHIN M | 2006 | Journal of Clinical Microbiology2006，44，9： | 1 |
| 13 | Mutational analysis of ras gene famity in lung cancer in Thai显示文摘 | Wongsommart D Chaksangchaichot P | 2003 | Oncol Rep2003，10，： | 1 |
| 14 | hMSH2 gene alterations associated with recurrence of oral squamous cell carcinoma 显示文摘 | Sanguansin S Petmitr S Punyarit P | 2006 | J Exp Clin Cancer Res2006，25，2： | 1 |
| 15 | Prognostic value of DNA alterations on chromosome 17p13.2 for intrahepatic cholangiocarcinoma显示文摘AIM:To characterize and evaluate DNA alterations among intrahepatic cholangiocarcinoma (ICC) patients. METHODS:DNA from tumor and corresponding normal tissues of 52 patients was amplified with 33 arbitrary primers. The DNA fragment that alters most frequently in ICC was cloned,sequenced,and identified by comparison with known nucleotide sequences in the genome database (www.ncbi.nlm.nih.gov). The DNA copy numbers of the allelic alterations in cholangiocarcinoma were determined by quantitative real-time PCR and interpreted as allelic loss or DNA amplification by comparison with the reference gene. Associations between allelic imbalance and clinicopathological parameters of ICC patients were evaluated by χ2-test. The Kaplan-Meier method was used to analyze survival rates. RESULTS:From 33 primers,an altered DNA fragment (518 bp) amplified from BC17 random primer was found frequently in the tumors analyzed and mapped to chromosome 17p13.2. Sixteen of 52 (31%) cases showed DNA amplification,while 7 (13%) showed allelic loss. Interestingly,DNA amplification on chromosome 17p13.2 was associated with a good prognosis,median survival time (wk) of amp vs no amp was 44.14 vs 24.14,P=0.002; whereas allelic loss of this DNA sequence corresponded with a poor prognosis,median survival time (wk) of loss vs no loss was 18.00 vs 28.71,P=0.019). Moreover,Kaplan-Meier curves comparing the DNA alterations with survival depicted highly significant separation that the median survival time equal to DNAamplification,allelic loss,and normal was 44.14 wk,18.00 wk,and 24.29 wk,respectively (P=0.005). CONCLUSION:Alterations in the DNA sequence on chromosome 17p13.2 may be involved in cholangio-carcinogenesis,and could be used as a prognostic marker in the treatment of ICC patients. | Ubol Chuensumran Sopit Wongkham Chawalit Pairojkul Siri Chauin Songsak Petmitr | 2007 | World Journal of Gastroenterology2007，13，21： | 0 |
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