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| 1 | Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy显示文摘我们与优先的主要雄激素剥夺治疗(ADT ) 在变形前列腺癌症在前进木头(PSAVAP ) 以后调查了前列腺特定的抗原天底(TTPN ) 和前列腺特定的抗原速度的对数的时间的协会。从 2000 ~ 2009 与主要 ADT 对待的所有变形前列腺癌症病人被考察。开发了疾病前进的病人在随后的分析被包括。病人们根据他们的 TTPN 被分成三个组:< 的 TTPN; 3 个月, 3-17 月,和 > 17 个月。我们用 Mann-Whitney U-test 和 Kruskal-Wallis 测试比较了在不同 TTPN 组之间的木头(PSAVAP ) 。木头(PSAVAP ) 上的进一步多重的线性回归分析被执行为使因素惊讶的另外的潜力调整。在与主要 ADT 被对待的 419 个病人之中, 306 个病人与 28 个月的中部的后续开发了疾病前进。更长的 TTPN 与更低的木头(PSAVAP ) 被联系(P = 0.008 ) 在所有亚群分析以内(< 的 TTPN; 3 对 3-17 月, P = 0.020;3-17 对 > 的 TTPN; 17 个月, P = 0.009;并且 < 的 TTPN; 3 对 > 17 个月, P = 0.001 ) 。在多重线性回归分析之上,基线 PSA (回归系数 0.001 , P = 0.045 ), PSA 天底(回归系数 0.002 , P = 0.040 ),并且 TTPN (回归系数 − ; 0.030 , P = 0.001 )是显著地与木头( PSAVAP )被联系的三个因素。在结论,更长的 TTPN 在跟随主要 ADT 的变形前列腺癌症病人与更低的木头(PSAVAP ) 被联系。在 3 个月和 17 个月的 TTPN cut-offs 看起来在预言木头(PSAVAP ) 有预示的意义。TTPN 可以在与疾病前进在病人决定治疗策略用作好预示的指示物。 | Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 6 |
| 2 | 16-dimethyl porstalandine2deceases the formation of fobrotie ratliver slice显示文摘 | Peter KM Snytder KF Rush BD Runat MU Henley KS 16 | 1989 | Prostaglandin1989，037，2： | 1 |
| 3 | GDF-5 and BMP- 2 regulate bone cell differentiation by gene expression of MSX1,MSX2,Dlx5 and Runx2 and influence OCN gene expression in vitro 显示文摘 | Peter KF Christoph W Elisabeth H | 2012 | Int J Periodontics Restorative Dent2012，32，3： | 1 |
| 4 | Apolipoprotein C3 genevariants in nonalcoholic fatty liver disease 显示文摘 | Peter sen KF Dufour S Hariri A | 2010 | N Engl J Med2010，362，： | 1 |
| 5 | 16,16-dimethyl prostglandin E 2 delays collagen formation in nutritional injury in rat liver显示文摘 | Ruwart MJ Rush BD Snyder KF Peters KM Appehman HD | 1988 | Hepatology1988，8，： | 1 |
| 6 | Process studies in genetic counseling显示文摘 | Biesecker BB Peters KF | 2001 | Am J Med Genet2001，106，3： | 1 |
| 7 | Increased adherence of fluconazole-resistant isolates of candida species to explanted esophageal mucosa显示文摘 | Lyman CA Garrett KF Peter J | 1999 | Eur Clin Microbiol Infect Dis1999，18，3： | 1 |
| 8 | Immunohistochemical stains in extramammary Paget's disease显示文摘 | Helm KF Goellner JR Peters MS | 1992 | Am J Dermatopathol1992，14，5： | 1 |
| 9 | Development of a scale to assess the background, needs, and expectations of genetic counseling clients 显示文摘 | Peters KF Petrill SA | 2011 | Am J Med Genet A2011，4，155： | 1 |
| 10 | Burd Human Papilloma- virus and cervical caneer显示文摘 | Peter KF Eileen M | 2003 | Clin Mierobiol- Rev2003，，： | 1 |
| 11 | Clinical differentiation between Proteus syndrome and hemihyperplasia:description of a distinct form of hemihyperplasia显示文摘 | Biesecker LG Peters KF Darling TN | 1998 | Am J Med Genet1998，79，4： | 1 |
| 12 | Sudden death caused by pulmonary thromboembolism in Proteus syndrome显示文摘 | Slavotinek AM Vacha SJ Peters KF | 2001 | Clin Genet2001，58，： | 1 |
| 13 | An opportunityfor genetic counseling intervention :Depression in parents of individuals with Proteus syndrome显示文摘 | Peters KF Biesecker LG | 2000 | J Genet Couns2000，9，： | 1 |
| 14 | Risk of cardiovascular thrombotic events after surgical castration versus gonadotropin-releasing hormone agonists in Chinese men with prostate cancer显示文摘我们与前列腺癌症在中国人在外科的阉割(SC ) 对释放 gonadotropin 荷尔蒙收缩筋(GnRHa ) 以后调查了心血管的 thrombotic 风险。从 2000 年与 SC 或 GnRHa 被对待到 2009 的所有中国前列腺癌症病人被考察并且比较。主要结果是在 SC 或 GnRHa 以后的心血管的 thrombotic 事件新发作的任何东西,它被定义为尖锐心肌的梗塞或 ischemic 击的任何事件。新发作的心血管的 thrombotic 事件的风险用 Kaplan-Meier 方法在 SC 组和 GnRHa 组之间被比较。穆尔蒂瓦里伊特·考克斯回归分析被执行为使因素惊讶的另外的潜力调整。684 个中国病人的一个总数在我们的学习被包括,包括在 SC 组的 387 个病人和在 GnRHa 组的 297 个病人。在 SC 组的吝啬的年龄(75.3 ±7.5 年) 比 GnRHa 组显著地高(71.8 ±8.3 年)(P <0.001 ) 。当时,有在 SC 组的新心血管的 thrombotic 事件的增加的风险与在 Kaplan-Meier 分析之上的 GnRHa 组相比(P = 0.014 ) 。在 multivariate 考克斯回归分析之上,变老(危险比率[HR ] 1.072, 95% 信心间隔[CI ] 1.04-1.11, P<0.001 ) , hyperlipidemia (HR 2.455, 95% CI 1.53-3.93, P<0.001 ) ,并且 SC (HR 1.648, 95% CI 1.05-2.59, P = 0.031 ) 是心血管的 thrombotic 事件的重要风险因素。在结论, SC 与心血管的 thrombotic 事件的增加的风险被联系什么时候与 GnRHa 相比。当决定雄激素剥夺治疗的方法时,这是一个重要方面考虑,特别在有 hyperlipidemia 的已知的历史的老人。 | Jeremy YC Teoh Samson YS Chan Peter KF Chiu Darren MC Poon Ho-Yuen Cheung Simon SM Hou Chi-Fai Ng | 2015 | Asian Journal of Andrology2015，17，3： | 0 |
| 15 | Time trend and characteristics of prostate cancer diagnosed in Hong Kong(China)in the past two decades显示文摘Dear Editor, Prostate cancer is an important disease worldwide)In 2015 it was the third most common cancer diagnosed in male in Hong Kong (China) and the incidence of prostate cancer has been rising in the past 15 years. Meanwhile,with increasing public awareness,health education, presentation,and detection of prostate cancer maybe changed.Therefore, we would like to review how the epidemiology of prostate cancer in Hong Kong (China)had changed in the past two decades. | Ho-Fai Wong Chi-Hang Yee Jeremy YC Teoh Samson YS Chan Peter KF Chiu Ho-Yuen Cheung Simon SM Hou Chi Fai Ng | 2019 | Asian Journal of Andrology2019，21，1： | 0 |
| 16 | The combined role of MRI prostate and prostate health index in improving detection of significant prostate cancer in a screening population of Chinese men显示文摘Using prostate-specific antigen(PSA)for prostate cancer(PCa)screening led to overinvestigation and overdiagnosis of indolent PCa.We aimed to investigate the value of prostate health index(PHI)and magnetic resonance imaging(MRI)prostate in an Asian PCa screening program.Men aged 50–75 years were prospectively recruited from a community-based PSA screening program.Men with PSA 4.0–10.0 ng ml^(−1) had PHI result analyzed.MRI prostate was offered to men with PSA 4.0–50.0 ng ml−1.A systematic prostate biopsy was offered to men with PSA 4.0–9.9 ng ml^(−1) and PHI≥35,or PSA 10.0–50.0 ng ml^(−1).Additional targeted prostate biopsy was offered if they had PI-RADS score≥3.Clinically significant PCa(csPCa)was defined as the International Society of Urological Pathology(ISUP)grade group(GG)≥2 or ISUP GG 1 with involvement of≥30%of total systematic cores.In total,12.8%(196/1536)men had PSA≥4.0 ng ml^(−1).Among 194 men with PSA 4.0–50.0 ng ml^(−1),187(96.4%)received MRI prostate.Among them,28.3%(53/187)had PI-RADS≥3 lesions.Moreover,7.0%(107/1536)men were indicated for biopsy and 94.4%(101/107)men received biopsy.Among the men received biopsy,PCa,ISUP GG≥2 PCa,and csPCa was diagnosed in 42(41.6%),24(23.8%),and 34(33.7%)men,respectively.Compared with PSA/PHI pathway in men with PSA 4.0–50.0 ng ml^(−1),additional MRI increased diagnoses of PCa,ISUP GG≥2 PCa,and csPCa by 21.2%(from 33 to 40),22.2%(from 18 to 22),and 18.5%(from 27 to 32),respectively.The benefit of additional MRI was only observed in PSA 4.0–10.0 ng ml^(−1),and the number of MRI needed to diagnose one additional ISUP GG≥2 PCa was 20 in PHI≥35 and 94 in PHI<35.Among them,45.4%(89/196)men with PSA≥4.0 ng ml^(−1) avoided unnecessary biopsy with the use of PHI and MRI.A screening algorithm with PSA,PHI,and MRI could effectively diagnose csPCa while reducing unnecessary biopsies.The benefit of MRI prostate was mainly observed in PSA 4.0–9.9 ng ml^(−1) and PHI≥35 group.PHI was an important risk stratification step for PCa screening. | Peter KF Chiu Thomas YT Lam Chi-Fai Ng Jeremy YC Teoh Carmen CM Cho Hiu-Yee Hung Cindy Hong Monique J Roobol Winnie CW Chu Samuel YS Wong Joseph JY Sung | 2023 | Asian Journal of Andrology2023，25，6： | 0 |
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