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| 1 | 山西五台山-恒山地区晚太古-早元古代若干关键地质问题的再认识:单颗粒锆石离子探针质谱年龄提出的地质制约显示文摘大量准确度很高的单颗粒锆石迅谱 (SHRIMP)年代学数据表明 ,五台山 -恒山绿岩带形成于 2 50 0 Ma之前 ,五台山 -恒山绿岩带形成后即与较老的阜平块体拼合。因此 ,该过程中有大量火山 ,深成活动及变质作用 ,是一次重要的造山运动。在 1 80 0 Ma之前 ,本区还经历了一次明显的构造热事件 ,主要表现为在地壳较深水平上大规模的冲断作用 ,使原来为不同地壳水平的块体处于同一地壳水平。本文还对原五台群下部层位板峪口组和金岗库组的归属及铁堡不整合面提出了新的看法。 | 王凯怡 郝杰 Simon Wilde Peter Cawood | 2000 | 地质科学2000，35，2： | 76 |
| 2 | Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study显示文摘 | Olivier Rixe Ronald M Bukowski M Dror Michaelson George Wilding Gary R Hudes Oliver Bolte Robert J Motzer Paul Bycott Katherine F Liau James Freddo Peter C Trask Sinil Kim Brian I Rini | 2007 | Lancet Oncology2007，，： | 2 |
| 3 | National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1 – executive summary显示文摘 | Terry A. Jacobson Matthew K. Ito Kevin C. Maki Carl E. Orringer Harold E. Bays Peter H. Jones James M. McKenney Scott M. Grundy Edward A. Gill Robert A. Wild Don P. Wilson W. Virgil Brown | 2014 | Journal of Clinical Lipidology2014，，： | 2 |
| 4 | HRS/EHRA/APHRS Expert Consensus Statement on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes显示文摘 | Silvia G. Priori Arthur A. Wilde Minoru Horie Yongkeun Cho Elijah R. Behr Charles Berul Nico Blom Josep Brugada Chern-En Chiang Heikki Huikuri Prince Kannankeril Andrew Krahn Antoine Leenhardt Arthur Moss Peter J. Schwartz Wataru Shimizu Gordon Tomaselli | 2013 | Heart Rhythm2013，，8： | 2 |
| 5 | Development of and Prospects for Cruising in Europe 显示文摘 | Peter Wild John bearing | 2000 | Maritime Policy & Management2000，27，4： | 1 |
| 6 | Geology and timing of mineralization at the Cangshang gold deposit, north-western Jiaodong Peninsula, China显示文摘 | Xiao’ou Zhang Peter A. Cawood Simon A. Wilde Ruqi Liu Hailin Song Wen Li Lawrence W. Snee | 2003 | Mineralium Deposita2003，，2： | 1 |
| 7 | p14 ARF and p16 INK4A , two products of the same gene, are differently expressed in cervical intraepithelial neoplasia显示文摘 | Johan Bulten Irene A.M. van der Avoort Willem J.G. Melchers Leon F.A.G. Massuger Johanna M.M. Grefte Antonius G.J.M. Hanselaar Peter C.M. de Wilde | 2005 | Gynecologic Oncology2005，，3： | 1 |
| 8 | Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction显示文摘 | HARVEY D. WHITE ROBIN M. NORRIS MICHAEL A. BROWN PETER W. T. BRANDT RALPH M. L. WHITLOCK CHRISTOPHER J. WILD | 1987 | Circulation1987，，1： | 1 |
| 9 | On modeling of the weld line in finite element analyses of tailor-welded blank forming operations显示文摘 | Raymond Scott D Wild Peter M Bayley Christopher J | 2004 | Journal of Materials Processing Technology2004，147，1： | 1 |
| 10 | Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes显示文摘 | Silvia G. Priori Arthur A. Wilde Minoru Horie Yongkeun Cho Elijah R. Behr Charles Berul Nico Blom Josep Brugada Chern-En Chiang Heikki Huikuri Prince Kannankeril Andrew Krahn Antoine Leenhardt Arthur Moss Peter J. Schwartz Wataru Shimizu Gordon Tomaselli | 2013 | Europace2013，，： | 1 |
| 11 | Archean blocks and their boundaries in the North China Craton: lithological, geochemical, structural and P-T path constraints and tectonic evolution 显示文摘 | ZHAO GUOCHUN WILDE SIMON A PETER A | 2001 | Precambrian Research2001，107，： | 1 |
| 12 | Effectiveness, safety, and drug sustainability of biologics in elderly patients with inflammatory bowel disease: A retrospective study显示文摘BACKGROUND Biologic therapy resulted in a significant positive impact on the management of inflammatory bowel disease(IBD) however data on the efficacy and side effects of these therapies in the elderly is scant.AIM To evaluate retrospectively the drug sustainability, effectiveness, and safety of the biologic therapies in the elderly IBD population.METHODS Consecutive elderly(≥ 60 years old) IBD patients, treated with biologics [infliximab(IFX), adalimumab(ADAL), vedolizumab(VDZ), ustekinumab(UST)] followed at the McGill University Inflammatory Bowel Diseases Center were included between January 2000 and 2020.Efficacy was measured by clinical scores at 3, 6-9 and 12-18 mo after initiation of the biologic therapy. Patients completing induction therapy were included. Adverse events(AEs) or serious AE were collected during and within three months of stopping of the biologic therapy.RESULTS We identified a total of 147 elderly patients with IBD treated with biologicals during the study period, including 109 with Crohn’s disease and 38 with ulcerative colitis. Patients received the following biologicals: IFX(28.5%), ADAL(38.7%), VDZ(15.6%), UST(17%). The mean duration of biologic treatment was 157.5(SD = 148) wk. Parallel steroid therapy was given in 34% at baseline,19% at 3 mo, 16.3% at 6-9 mo and 6.5% at 12-18 mo. The remission rates at 3, 6-9 and 12-18 mo were not significantly different among biological therapies. Kaplan-Meyer analysis did not show statistical difference for drug sustainability(P = 0.195), time to adverse event(P = 0.158) or infection rates(P = 0.973) between the four biologics studied. The most common AEs that led to drug discontinuation were loss of response, infusion/injection reaction and infection.CONCLUSION Current biologics were not different regarding drug sustainability, effectiveness, and safety in the elderly IBD population. Therefore, we are not able to suggest a preferred sequencing order among biologicals. | Gustavo Drugg Hahn Jean-Frederic LeBlanc Petra Anna Golovics Panu Wetwittayakhlang Abdulrahman Qatomah Anna Wang Levon Boodaghians Jeremy Liu Chen Kiow Maryam Al Ali Gary Wild Waqqas Afif Alain Bitton Peter Laszlo Lakatos Talat Bessissow | 2022 | World Journal of Gastroenterology2022，28，33： | 1 |
| 13 | Deletions at chromosome 2q and 12p are early and frequent molecularalterations in bronchial epithelium and NSCLC of long-term smokers显示文摘 | Ulrike Grepmeier Wolfgang Dietmaier Johannes Merk Peter Wild Ellen Obermann Michael Pfeifer Ferdinand Hofstaedter Arndt Hartmann Matthias Woenckhaus | 2005 | International Journal of Oncology2005，，2： | 1 |
| 14 | Fast rise time,long pulse width,kilohertz repetition rate Q-switch driver显示文摘 | Thomas P Rutten Neville Wild Peter J Veitch | | 0，，07： | 1 |
| 15 | Trends of diverticular disease of the large bowel in a newly developed country显示文摘 | John G. Chia M.B.B.S. Chintana C. Wilde M.D. Sing S. Ngoi F.R.C.S. Peter M. Goh F.R.C.S. Chong L. Ong F.R.C.S | 1991 | Diseases of the Colon & Rectum1991，，6： | 1 |
| 16 | Pancreaticoduodenal endocrine tumors in multiple endocrine neoplasia type 1: Surgery or surveillance?显示文摘 | Detlef K. Bartsch Peter Langer Anja Wild Thomas Schilling Ilhan Celik Matthias Rothmund Christoph Nies | 2000 | Surgery2000，，6： | 1 |
| 17 | On modeling of the weld line in finite element analyses of tailor-welded blank forming operations 显示文摘 | RAYMOND Scott D WILD Peter M BAYLEY Christopher J | 2004 | Journal of Materials Processing Technology2004，147，： | 1 |
| 18 | Competitive adsorp- tion of proteins with methylcellulose and hydroxypropyl methylcellulose 显示文摘 | Arboleya Juan-Carlos Wilde Peter J | 2005 | Food Hydrocolloids2005，19，3： | 1 |
| 19 | Development of a new engineering-based capsule for human drug absorption studies显示文摘 | Ian Wilding Peter Hirst Alyson Connor | | 0，，311： | 1 |
| 20 | Development of a new engineering based capsule for human drug absorption studies 显示文摘 | Ian Wilding Peter Hirst Alyson Connor | 2000 | Pharmaceutical Science & Technology Today2000，3，11： | 1 |
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