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| 1 | Superior safety of direct oral anticoagulants compared to Warfarin in patients with atrial fibrillation and underlying cancer: a national veterans affairs database study显示文摘Background Studies evaluating safety of warfarin and direct oral anticoagulants(DOACs) for prevention of stroke in patients with atrial fibrillation(AF) are lacking. Methods & Results All patients(n = 196,521) receiving care at veteran’s affairs with active cancer and AF from 2010–2015 were included. One-year mortality was significantly higher in unadjusted analysis with warfarin(44.9%) compared to dabigatran(25%, P < 0.001), rivaroxaban(24.4%, P < 0.001) and apixaban(30%, P < 0.001) and after adjusting for age, sex and type of cancer mortality(OR = 2.66, 95% CI: 2.52–2.82, P < 0.001). Risk of ischemic stroke(13.5% vs. 11.1%, 12.0%, 14.0%) was similar, however risk of hemorrhagic stroke was significantly higher among patients receiving warfarin(1.2%) compared to patients receiving dabigatran(0.5%), rivaroxaban(0.7%) and apixaban(0.8%) respectively, P = 0.04. Conclusions We demonstrated the superior safety profile of DOACs compared to warfarin among patients with underlying cancer and AF. Warfarin was associated with higher mortality, similar ischemic stroke risk but higher risk of hemorrhagic stroke. | Abhishek C Sawant Arnav Kumar Wilmon Mccray Sheldon Tetewsky Linda Parone Srilekha Sridhara Meghana Prakash Hiriyur Prakash Gary Tse Tong LIU Nidhi Kanwar Aishwarya Bhardwaj Sahoor Khan Christopher Manion Ankush Lahoti Ashish Pershad Peter Elkin John Corbelli | 2019 | Journal of Geriatric Cardiology2019，16，9： | 2 |
| 2 | ARHI is the center of allelic deletion on chromosome 1 p31 in ovarian and breast cancers显示文摘 | Peng H Xu F Pershad R | 2000 | Int J Cancer2000，86，5： | 1 |
| 3 | ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers显示文摘 | Peng H Xu F Pershad R | 2000 | Int J Cancer2000，86，5： | 1 |
| 4 | The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear 显示文摘 | Pershad J | 2015 | Evid Based Med2015，20，1： | 1 |
| 5 | One-year outcomes for reeanalization of long superficial femoral artery chronic total occlusions with the Viabahn stent graft 显示文摘 | Farraj N Srivastava A Pershad A | 2009 | J Invasive Cardiol2009，21，6： | 1 |
| 6 | Comparison of propofol with pentobarbital/midazolarfdfentanyl sedation for magnetic resonance imaging of the brain in childrenp 显示文摘 | Pershad J Wan J Anghelescu DL | 2007 | Pediatrics2007，120，2： | 1 |
| 7 | Gene expression in the developing mouse retina by EST sequencing and microarray analysis显示文摘 | Mu X Zhao S Pershad R | | 0，，： | 1 |
| 8 | Immediate and short-term outcome following recanalization of long chronic total occlusions ( > 50 mm) of native coronary arteries with the Frontrunner catheter 显示文摘 | Loll A Liu R Pershad A | 2006 | J Invasire Cardiol2006，18，6： | 1 |
| 9 | ARH I is the center of allelic deletion on chromosome 1 p31 in ovarian and breast cancers显示文摘 | Peng H Xu F Pershad R | 2000 | Int J Cancer2000，86，5： | 1 |
| 10 | Immediate- and short-term outcome following recanalization of long chronic total occlusions ( > 50 mm) of native coronary arteries with the Frontrunner catheter显示文摘 | Loli A Liu R Pershad A | 2006 | J Invasive Cardiol2006，18，6： | 1 |
| 11 | The effects of modulating eNOS activity and coupling in ischemia/reperfusion (I/R)显示文摘 | Perkins KA Pershad S Chen Q | 2012 | Naunyn Schmiedebergs Arch Pharmacol2012，385，1： | 1 |
| 12 | One year outcomes for recanal- ization of long superficial femoral artery chronic total occlusions with the Viabahn stcnt graft 显示文摘 | Farraj N Srivastava A Pershad A | 2009 | J Invasive Cardiol2009，21，6： | 1 |
| 13 | Immediate and short-term outcome following recanalization of long chronic total occlusions( > 50 mm) of native coronary arteries with the Frontrunner catheter显示文摘 | Loli A Liu R Pershad A | 2006 | J Invasive Cardiol2006，18，6： | 1 |
| 14 | Management of calcified lesions in,2004显示文摘 | Pershad A Buchbinder M | | 0，，： | 1 |
| 15 | Pre-operative anxiety,effect of early or late position on the operation list显示文摘 | Panda N Bajaj A Pershad D | 1996 | Anaesthesia1996，51，4： | 1 |
| 16 | Comparison of propofol with pentobarbital/midazolam/fentanyl se- dation for magnetic resonance imaging of the brain in children 显示文摘 | Pershad J Wan J Anghelescu DL | 2007 | Pediatrics2007，120，： | 1 |
| 17 | Cost-effectiveness analysis of anesthetic agents during peripheral intravenous cannulation in the pediatric emergency department显示文摘 | Pershad J Steinberg SC Waters TM | 2008 | Arch Pediatr Adolesc Med2008，162，10： | 1 |
| 18 | Manage- ment of distal coronary perforations显示文摘 | PERSHAD A YARKONI A BIGLARI D | 2008 | J Invasive Aardiol2008，20，： | 1 |
| 19 | Detection and interpretation of redox potential optima in the catalytic activity of enzymes 显示文摘 | Elliott S J Leger C Pershad H R | 2002 | Biochim Biophys Acta2002，1555，1： | 1 |
| 20 | Detection and interpretation of redox potential optima in the catalytic activity of enzymes显示文摘 | ELLIOTT S J LéGER C PERSHAD H R | 2002 | Biochimica et Biophysica Acta2002，1555，： | 1 |
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