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54篇 您的检索式：作者名="Penke"

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	题名	作者	年代	出处	被引量
1	A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis显示文摘AIM: To assess the effect of our novel cell-permeable nuclear factor-kappaB (NF-κB) inhibitor peptide PN50 in an experimental model of acute pancreatitis. PN50 was produced by conjugating the cell-penetrating penetratin peptide with the nuclear localization signal of the NF-κB p50 subunit.METHODS: Pancreatitis was induced in male Wistar rats by administering 2×100 μg/kg body weight of cholecystokininoctapeptide (CCK) intraperitoneally (IP) at an interval of 1 h. PN50-treated animals received 1 mg/kg of PN50 IP 30 min before or after the CCK injections. The animals were sacrificed 4 h after the first injection of CCK.RESULTS: All the examined laboratory (the pancreatic weight/body weight ratio, serum amylase activity,pancreatic levels of TNF-α and IL-6, degree of lipid peroxidation, reduced glutathione levels, NF-κB binding activity, pancreatic and lung myeloperoxidase activity) and morphological parameters of the disease were improved before and after treatment with the PN50 peptide.According to the histological findings, PN50 protected the animals against acute pancreatitis by favoring the induction of apoptotic, as opposed to necrotic acinar cell death associated with severe acute pancreatitis.CONCLUSION: Our study implies that reversible inhibitors of stress-responsive transcription factors like NF-κB might be clinically useful for the suppression of the severity of acute pancreatitis.	Tamás Letoha Csaba Somlai Tamáas Takács Annamária Szabolcs Katalin Jármay Zoltán Rakonczay Jr Péter Hegyi Ilona Varga József Kaszaki István Krizbai Imre Boros Ern(?) Duda Erzsébet Kusz Botond Penke	2005	World Journal of Gastroenterology2005，11，7：	15
2	Brain white matter tract integrity as a neural foundation for general intelligence 显示文摘	Penke L Mauiega S Bastin ME	2012	Molecular Psychiatry2012，17，10：	1
3	Topologically Interesting Cages of Negative Ions with Extremely High 'Coordination Number' :an unuasual property of V-O clusters 显示文摘	Muller A Penk M Rohlfing R	2003	Angewandte Chemie International Edition in English2003，29，3：	1
4	Serum proinflammatory cytokine levels and white blood cell diferential count in patients with different degrees of severity of acute alcoholic pancreatitis显示文摘	Penk J Kusnierz-Cabala B Dolecki M	2012	Pol Przegl Chir2012，84，5：	1
5	Fluctuating asymmetry and personality显示文摘	Hope D Bates T Penke L		0，，01：	1
6	A modified, optimized kinetic photometric assay for the determination of blobd coagulation factor Ⅻ in plasma显示文摘	Karpati E Penke B Katona E	2000	Clin Chem2000，46，：	1
7	Rb-Sr dating of sphalerite based on fluid inclusion-host mineral isochrons: A clarification of why it works 显示文摘	Penke K Diamond L W	1996	Economic Geology1996，91，：	1
8	Preparation and analyti- cal data of some unusual amino acid derivatives used in peptide syntheses 显示文摘	Penke B Czornbos J Balaspiri L	1970	Helv Chim Aeta1970，53，：	1
9	Pre-treatment and post-treatment with a- tocopherol attenuates hippoeampal neuronal damage in experimental cerebral hypoperfusion 显示文摘	Annahdzi A Mracsk6 E Stile Z Karg E Penke B Bari F	2007	Eur J Pharmacol2007，571，：	1
10	The pore size of PLGA bone implants determines the de novo formation of bone tissue in tibial head defects in rats显示文摘	Penk A Forster Y Seheidt HA	2013	MagnReson Med2013，70，4：	1
11	Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane:binding sites and implications for Alzheimer's disease显示文摘	Verdier Y Zarandi M Penke B		0，，05：	1
12	Topologically interesting cages of negative ions with extremely high ' coordination number'; an unusual property of V-O clusters 显示文摘	Muller A Penk M Rohlfing R	1990	Angew Chem Int Ed1990，29，：	1
13	Topologically interesting cages of negative ions with extremely high 'coordination number' : an unuasual property of V-O clusters 显示文摘	Miiller A Penk M Rohlfing R	2003	Angewandte Chemie International Edition in English2003，29，3：	1
14	Polarographic detection of nitric oxide released from cardiovascular compounds in aqueous solutions显示文摘	Pataricza J Penke B Balogh GE	1998	J Pharmacol Toxicol Methods1998，39，2：	1
15	Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta-amyloid peptide显示文摘	Verdier Y Huszar E Penke B	2005	J Neurochem2005，94，3：	1
16	Evaluation of deprivation manifestations of the auditory system in patients with unilateral middle ear deafness before and after surgical therapy显示文摘	Penk S Brosz M	1996	Laryngorhinootologie1996，75，：	1
17	Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: Binding sites and implications for Alzheimer's disease显示文摘	Verdier Y Zarandi M Penke B	2004	J Pept Sci2004，10，：	1
18	Amyloid β-peptide interactions with neuronal and glial cell plasma membrane:binding sites and implications for Alzheimer's disease显示文摘	Verdier Y Zarandi M Penke B	2004	Peptide Sci2004，10，5：	1
19	Therapeutic experience with fluconazole in the treatment offungal infections in diabetic patients显示文摘	Penk A Pittrow L	1999	Mycoses1999，42，：	1
20	A general factor of brain white matter integrity predicts information processing speed in healthy older people显示文摘	Penke L Maniega SM Murray C	2010	J Neuroscience2010，30，：	1

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