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| 1 | Climatic Warming and Humidification in the Arid Region of Northwest China: Multi-Scale Characteristics and Impacts on Ecological Vegetation显示文摘The climatic warming and humidification observed in the arid region of Northwest China(ARNC) and their impacts on the ecological environment have become an issue of concern. The associated multi-scale characteristics and environmental responses are currently poorly understood. Using data from satellite remote sensing, field observations, and the Coupled Model Intercomparison Project phase 6, this paper systematically analyzes the process and scale characteristics of the climatic warming and humidification in the ARNC and their impacts on ecological vegetation. The results show that not only have temperature and precipitation increased significantly in the ARNC over the past 60 years, but the increasing trend of precipitation is also obviously intensifying. The dryness index, which comprehensively considers the effects of precipitation and temperature, has clearly decreased, and the trend in humidification has increased. Spatially, the trend of temperature increase has occurred over the entire region, while 93.4% of the region has experienced an increase in precipitation, suggesting a spatially consistent climatic warming and humidification throughout the ARNC. Long-term trends and interannual changes in temperature and precipitation dominate the changes in climatic warming and humidification. Compared to interannual variations in temperature, the trend change of temperature contributes more to the overall temperature change. However, the contribution of interannual variations in precipitation is greater than that of the precipitation trend to the overall precipitation change. The current climatic warming and humidification generally promote the growth of ecological vegetation. Since the 1980 s,82.4% of the regional vegetation has thrived. The vegetation index has a significant positive correlation with precipitation and temperature. However, it responds more significantly to interannual precipitation variation, although the vegetation response varies significantly under different types of land use. The warming and humidification of the climate in the ARNC are probably related to intensifications of the westerly wind circulation and ascending air motions.They are expected to continue in the future, although the strength of the changes will probably be insufficient to significantly change the basic climate pattern in the ARNC. The results of this study provide helpful information for decision making related to China's 'Belt and Road' development strategies. | Qiang ZHANG Jinhu YANG Wei WANG Pengli MA Guoyang LU Xiaoyun LIU Haipeng YU Feng FANG | 2021 | Journal of Meteorological Research2021，35，1： | 19 |
| 2 | Mesoporous silica nanorods intrinsically doped with photosensitizers as a multifunctional drug carrier for combination therapy of cancer显示文摘Mesoporous 硅石 nanoparticles (MSN ) 由于他们的大表面区域,悦耳的尺寸,灵巧的修正和可观的 biocompatibility 作为药交货搬运人在最近的年里吸引了巨大的注意。在这个工作,我们制作内在地与使分子具有感光性被做的 MSN 的一种有趣的类型,氯 e6 (Ce6 ) 。由增加在硅石矩阵内做的 Ce6 的数量, MSN 的形态学从范围改变到像杆的形状,这被发现。获得的做 Ce6 的 mesoporous 硅石 nanorods (CMSNR ) 不仅能为光力学的治疗,而且罐头生产汗衫氧也与由利用他们的 mesoporous 结构装载能力的高药用作一个药交货平台。比作球形的 nanoparticles,有更大的方面比率的 CMSNR 由癌症房间显示出许多更快的举起,这被发现。与作为模型药采用的 doxorubicin (纪录影片) ,联合光力学并且化疗被执行,在 vitro 并且在 vivo 完成 synergistic 反肿瘤效果。我们的学习介绍一个基于 MSN 的药交货平台的一个新图案,它内在地荧光灯、有能力用作一个光力学的代理人,为未来答应癌症的指导成像的联合治疗。 | Guangbao Yang Hua Gong Xiaoxin Qian Pengli Tan Zhiwei Li Teng Liu Jingjing Liu Youyong Li Zhuang Liu | 2015 | Nano Research2015，8，3： | 11 |
| 3 | Highly sensitive flexible capacitive pressure sensor with a broad linear response range and finite element analysis of micro-array electrode显示文摘With the continuous development of wearable electronics,health care and smart terminals,highly performance flexible pressure sensors present a huge application prospect.In this study,by introducing the micro-array structured electrodes and dielectric layers with high dielectric constant,capacitive pressure sensor fabricated with a brand new preparation strategy and highly sensitive is proposed.The prepared micro-array structure is the basis for sensors with high sensitivity.Besides,the contact area between the two electrodes changes from linear to planar with the increased loading,which result in a wider linear responding range.In addition,by introducing ceramic dielectric material-barium titanate(BT)fillers into the dielectric layer to increase it’s the dielectric constant,the sensitivity of the sensor shows two-fold increase.Moreover,the sensitivity gradients can be tuned by changing the loading contents of BT particles.Hence,compared with parallel board capacitive sensors with ordinary dielectric layer,these sensors exhibit excellent performance as follow,high sensitivity(up to 4.9 kPa^(-1))under low pressure range(0-2500 Pa),low detection limit(<1.7 Pa),short response time(<50 ms),a stable response over 5000 loading-unloading cycles,bending stability and an adjustable sensitivity.Further,the flexible pressure sensor can detect the pressure of the water droplets and monitor human movement behavior.With the facile design and excellent comprehensive properties,the flexible pressure sensor provides a new approach to improve the sensitivity and shows a broad application prospects in the wearable electronics,health care and smart terminals. | Longquan Ma Xuecheng Yu Yuanyuan Yang Yougen Hu Xinyu Zhang Huayuan Li Xing Ouyang Pengli Zhu Rong Sun Ching-ping Wong | 2020 | Journal of Materiomics2020，6，2： | 4 |
| 4 | A Constant Potential Molecular Dynamics Simulation Study of the Atomic-Scale Structure of Water Surfaces Near Electrodes显示文摘Summary of main observation and conclusion Novel and technologically important processes and phenomena arise at water surfaces in the presence of electric fields.However,experimental measurements on water surfaces are challenging,and the results are scarce and inconclusive.In this work,the constant potential molecular dynamics method,in which the electrode charges are allowed to fluctuate to keep the electric potential fixed,was implemented in the study of a near-electrode water surface systems.This simulation system was set up with a vapor/liquid-water/vapor slab and two electrodes under different sets of applied electrostatic potential,yielding i)a detailed characterization of the external E-field dependent electrostatic potential/density/dipole moment density profiles,and ii)the relationship between the water surface width and the applied electrode voltage differences which has been rarely reported.The adjustments in the number density profiles in the vicinity of water surfaces due to external E-fields were observed,while the capillary interfacial widths for the surfaces near both cathode and anode were found with different increment rates under increasing E-fields.By examining dipole density profiles across the water surfaces,we found that external E-field induced polarization occurs in both bulk and surface regimes,yet the surface polarization densities vary asymmetrically with respect to the increasing E-fields.Detailed discussions were carried out to explain the correlation between water surface tension and surface widths,as well as the interplay between the surface polarization densities and the hydrogen bond network structure.We conclude that the mechanical and structural properties of the water surfaces could be tuned by both magnitude and direction of the strong external E-fields.We also recognize that more surface properties with application value,such as dielectric permittivity tensor or surface potential,could also be regulated by the external E-fields. | Pengli Yang Zhenxing Wang Zun Liang Hongtao Liang Yang Yang | 2019 | Chinese Journal of Chemistry2019，37，12： | 2 |
| 5 | TOF–SIMS surface analysis of chemical components of size–fractioned urban aerosols in a typical heavy air pollution event in Beijing显示文摘Size–fractioned atmospheric aerosol particles were collected during a typical heavy air pollution event in Beijing. The organic and inorganic components on the surfaces of the samples were analyzed using time–of–flight secondary ion mass spectrometry(TOF–SIMS).The variation characteristics of the surface chemical composition and influencing factors were studied, and the possible sources of these chemical compositions were identified through principal component analysis. The results showed that inorganic components such as crustal elements and sulfate, and organic components such as aliphatic hydrocarbons and oxygen–containing organic groups were present. Some surface components, such as polycyclic aromatic hydrocarbons, heavy metals and fluorides may exert adverse effects on human health. The species and relative percentages of the chemical components varied with particle size, diurnal and pollution progress. During a heavy pollution event, the species and relative percentages of secondary components such as oxygen–containing organic groups and sulfurous compounds increased, indicating that particles aged during this event. The surface chemical composition of the aerosol particles was affected mainly by emissions from coal combustion and motor vehicles. In addition, air pollution, meteorological factors, and air mass transport also exerted a significant effect on the surface chemical composition of aerosol particles. | Wenjun Li Hong Li Jinjuan Li Xueli Cheng Zhengzheng Zhang Fahe Chai Hao Zhang Ting Yang Pengli Duan Defeng Lu Yizhen Chen | 2018 | Journal of Environmental Sciences2018，30，7： | 2 |
| 6 | Preparation, Characterization and Pharmacokinetics of Fluorescence Labeled Propylene Glycol Alginate Sodium Sulfate显示文摘A rapid and sensitive fluorescence labeling method was developed and validated for the microanalysis of a sulfated polysaccharide drug,namely propylene glycol alginate sodium sulfate(PSS), in rat plasma. Fluorescein isothiocyanate(FITC) was selected to label PSS, and 1, 6-diaminohexane was used to link PSS and FITC in order to prepare FITC-labeled PSS(F-PSS) through a reductive amination reaction. F-PSS was identified by UV-Vis, FT-IR and 1H-NMR spectrum. The cell stability and cytotoxicity of F-PSS were tested in Madin-Darby canine kidney(MDCK) cells. The results indicated that the labeling efficiency of F-PSS was 0.522% ± 0.0248% and the absolute bioavailability was 8.39%. F-PSS was stable in MDCK cells without obvious cytotoxicity. The method was sensitive and reliable; it showed a good linearity, precision, recovery and stability. The FITC labeling method can be applied to investigating the absorption and metabolism of PSS and other polysaccharides in biological samples. | LI Pengli LI Chunxia XUE Yiting ZHANG Yang LIU Hongbing ZHAO Xia YU Guangli GUAN Huashi | 2014 | Journal of Ocean University of China2014，13，4： | 1 |
| 7 | Immunity phenomena following olfactory ensheathing cell transplantation into experimental allergic encephalomyelitis rat brain显示文摘Olfactory ensheathing cells(OECs) can promote axonal regeneration and remyelination for the treatment of spinal cord injury.OECs can also treat experimental allergic encephalomyelitis(EAE),but it remains unclear whether OECs might be rejected by the immune system in the brain including the destruction of the blood-brain barrier under inflammation,the release of inflammatory factors,the activation of local antigen-presenting cells(e.g.,microglia cells) and antigen drainage.We found that OECs expressed major histocompatibility complex(MHC)-I molecules on the cell surface,barely expressed MHC-Ⅱ,but MHC-Ⅱ could be induced by interferon-γ,suggesting that OECs have certain immunogenicity.When OECs were transplanted into normal animal brains,no OECs were phagocytosed by dendritic cells in the cervical lymph node,and OECs did not induce lymphocyte proliferation,which indicates that OECs share some immune privilege under normal conditions.However,OECs in the rat EAE brain were phagocytosed by dendritic cells in the cervical lymph node and enhanced lymphocyte proliferation.These findings suggest that OECs are rejected because of increased immunogenicity in EAE brain,and that brain inflammation,in particular activated dendritic cells,may be a prerequisite for rejecting OECs. | Ainong Mei Jue Wang Qiong Cheng Xinqing Yang Jin Yang Pengli Zhu Shougang Guo | 2010 | Neural Regeneration Research2010，5，15： | 1 |
| 8 | Luminescent gold nanocluster-based sensing platform for accurate H_(2)S detection in vitro and in vivo with improved anti-interference显示文摘Gold nanoclusters(Au NCs)are promising luminescent nanomaterials due to their outstanding optical properties.However,their relatively low quantum yields and environment-dependent photoluminescence properties have limited their biological applications.To address these problems,we developed a novel strategy to prepare chitosan oligosaccharide lactate(Chi)-functionalized Au NCs(Au NCs@Chi),which exhibited emission with enhanced quantum yield and elongated emission lifetime as compared to the Au NCs,as well as exhibited environment-independent photoluminescence properties.In addition,utilizing the free amino groups of Chi onto Au NCs@Chi,we designed a FRET-based sensing platform for the detection of hydrogen sulfide(H_(2)S).The Au NCs and the specific H_(2)S-sensitive merocyanine compound were respectively employed as an energy donor and acceptor in the platform.The addition of H_(2)S induced changes in the emission profile and luminescence lifetime of the platform with high sensitivity and selectivity.Utilization of the platform was demonstrated to detect exogenous and endogenous H_(2)S in vitro and in vivo through wavelength-ratiometric and time-resolved luminescence imaging(TLI).Compared to previously reported luminescent molecules,the platform was less affected by experimental conditions and showed minimized autofluorescence interference and improved accuracy of detection. | Qi Yu Pengli Gao Kenneth Yin Zhang Xiao Tong Huiran Yang Shujuan Liu Jing Du Qiang Zhao Wei Huang | 2017 | Light(Science & Applications)2017，6，1： | 1 |
| 9 | Induction and intracellular localization of Nur77 dictate fenretinide-induced apoptosis of human liver cancer cells显示文摘 | Hui Yang Nathan Bushue Pengli Bu Yu-Jui Yvonne Wan | 2009 | Biochemical Pharmacology2009，，7： | 1 |
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