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	题名	作者	年代	出处	被引量
1	Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study显示文摘AIM: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HNC) patients using videofluoroscopic swallow studies. METHODS: In this retrospective cohort study, video-fluoroscopic images of rt HNC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCR) was also measured to determine if weak pharyngeal constriction is associated with post radiation therapy.RESULTS: The rt HNC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P < 0.0001), normalized residue ratio scale(NRRS) for the valleculae(P = 0.002) and NRRS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PMS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HNC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HNC group(P < 0.0001). The PCR was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. CONCLUSION: Using videofluoroscopy, this study shows rt HNC patients have worse swallowing outcomes associated with reduced hyolaryngeal mechanics and pharyngeal constriction compared with controls.	William G Pearson Jr Alisa A Davidoff Zachary M Smith Dorothy E Adams Susan E Langmore	2016	World Journal of Radiology2016，8，2：	2
2	Critical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD kleefield SF Soukop JR	2001	Am J Med2001，110，：	1
3	Critical path- ways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，3：	1
4	Successful man-agement of bilateral carotid- caveenous fistulae with a trans-sphenoidal approach显示文摘	Laws Er Jr Onofrio Bm Pearson Bw	1979	Neurosurgery1979，4，2：	1
5	Critical pathways interven- tion to recluce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，3：	1
6	Critical pathways inter- vention to reduce length of hospital stay 显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，：	1
7	Critical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，：	1
8	Critical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	American journal of Medicine2001，110，3：	1
9	Fractures of the pelvis involving the floor of the acetabulum显示文摘	Pearson JR Hargadon EJ	1962	J Bone Joint Surg(Br)1962，44，3：	1
10	Work-family conflict:A model of linkages between work and famly domain variables and turnover intentions显示文摘	Boyar S L Maertz C P Jr Pearson A W	2003	Journal of Managerial issues2003，15，2：	1
11	Clinical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，3：	1
12	Principles for national and regional guidelines on cardiovascular disease prevention: a scientific statement from the World Heart and Stroke Forum显示文摘	Smith SC Jr Jackson R Pearson TA	2004	Circulation2004，109，25：	1
13	The ef- fects of work-family conflict and family-work con- flict on non-attendance behaviors显示文摘	Boyar S L Maertz Jr C P Pearson A	2005	Journal of business research2005，58，4：	1
14	Critical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，：	1
15	Critical pathways intervention to reduce length of hospital stay 显示文摘	Pearson SD gleefield SF Soukop JR	2001	Am J Med2001，110，3：	1
16	The effects of work - family conflict and family - work conflict on non - attendance behaviors 显示文摘	Boyar S L Maertz Jr C P Pearson A	2005	Journal of Business Research2005，58，4：	1
17	Clinical pathw- ays intervention to reduce length of hospital stay 显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，3：	1
18	Critical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD gleefield SF Soukop JR et aI	2001	Am J Med2001，110，3：	1
19	Clinical pathways intervention to reduce length of hospital stay显示文摘	Pearson SD Kleefield SF Soukop JR	2001	Am J Med2001，110，：	1
20	Critical path- ways intervention to reduce length of hospital stay 显示文摘	Pearson SD Kledleld SF Soukop JR	2001	The American Journal of Medicine2001，110，3：	1

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