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| 1 | Main causes of reduced intraocular pressure after excimer laser photorefractive keratectomy显示文摘 | Patel S and Aslanides IM | 1996 | J Refract Surg1996,12,6: | 1 |
| 2 | Common variation in the adi- ponect-in gene has an effect on systolic blood pressure显示文摘 | Aver PJ Patel SK Ibrahim IM | 2011 | J Hum Hypertens2011,25,12: | 1 |
| 3 | Treatment of the edentulous atrophic maxilla using zygomatic implants: evaluation of survival rates over 5-10 years 显示文摘 | Yates JM Brook IM Patel RR | 2014 | Int J Oral Maxillofac Surg2014,43,2: | 1 |
| 4 | Anti-canceractivity of anti-GLUT1 antibody -targeted polymeric mi-celles co-loaded with curcumin and doxorubicin显示文摘 | Abouzeid AH Patel NR Rachman IM | 2013 | J DrugTarget2013,21,10: | 1 |
| 5 | Main causes of reduced intraocular pressure after excimer laser photorefractive keratectomy显示文摘 | Patel S Aslanides IM | 1996 | J Refract Surg1996,12,: | 1 |
| 6 | Main causes of reduced intraocular pressure after excimer laser photorefractive keratectomy显示文摘 | Patel S Aslanides IM | 1996 | J Cataract Refract Surg1996,12,6: | 1 |
| 7 | Preparation and characterization of proton conducting polysulfone grafted poly(styrene sulfonie acid) polyelectrolyte membranes显示文摘 | Patel R Im S J Ko Y T | 2009 | Journal of Industrial and Engineering Chemistry2009,15,3: | 1 |
| 8 | Perioperative anxiety and postoperative behavioural disturbances in children undergoing intravenous or inhalation induction of anaesthesia 显示文摘 | Aguilera IM Patel D Meakin GH | 2003 | Paediatr Anaesth2003,13,6: | 1 |
| 9 | Factors associated with consumption of diabeticdiet among type 2 diabetic subjects from Ahmedabad, Western India 显示文摘 | Patel M Patel IM Patel YM | 2012 | J HealthPopul Nutr2012,30,4: | 1 |
| 10 | Endoscopic endonasal transclival transodontoid approach for ventral decompression of the craniovertebral junction: operative technique and nuances 显示文摘 | Liu JK Patel J Goldstein IM | 2015 | Neurosurg Focus2015,38,4: | 1 |
| 11 | Risk of intussusception following administration of a pentavalent rotavirus vaccine in US infants 显示文摘 | Shui IM Baggs J Patel M | 2012 | JAMA2012,307,6: | 1 |
| 12 | Hepatic decompensation/serious adverse events in post-liver transplantation recipients on sofosbuvir for recurrent hepatitis C virus显示文摘AIM: To determine the safety profile of new hepatitis C virus(HCV) treatments in liver transplant(LT) recipients with recurrent HCV infection.METHODS: Forty-two patients were identified with recurrent HCV infection that underwent LT at least 12 mo prior to initiating treatment with a Sofosbuvir-based regimen during December 2013-June 2014. Cases were patients who experienced hepatic decompensation and/or serious adverse events(SAE) during or within one month of completing treatment. Controls had no evidence of hepatic decompensation and/or SAE. HIVinfected patients were excluded. Cumulative incidence of decompensation/SAE was calculated using the Kaplan Meier method. Exact logistic regression analysis was used to identify factors associated with the composite outcome. RESULTS: Median age of the 42 patients was 60 years [Interquartile Range(IQR): 56-65 years], 33%(14/42) were female, 21%(9/42) were Hispanic, and 9%(4/42) were Black. The median time from transplant to treatment initiation was 5.4 years(IQR: 2.1-8.8 years). Thirteen patients experienced one or more episodes of hepatic decompensation and/or SAE. Anemia requiring transfusion, the most common event, occurred in 62%(8/13) patients, while 54%(7/13) decompensated. The cumulative incidence of hepatic decompensation/SAE was 31%(95%CI: 16%-41%). Risk factors for decompensation/SAE included lower pre-treatment hemoglobin(OR = 0.61 per g/d L, 95%CI: 0.40-0.88, P < 0.01), estimated glomerular filtration rate(OR = 0.95 per m L/min per 1.73 m^2, 95%CI: 0.90-0.99, P = 0.01), and higher baseline serum total bilirubin(OR = 2.43 per mg/d L, 95%CI: 1.17-8.65, P < 0.01). The sustained virological response rate for the cohort of 42 patients was 45%, while it was 31% for cases.CONCLUSION: Sofosbuvir/ribavirin will continue to be used in the post-transplant population, including those with HCV genotypes 2 and 3. Management of anemia remains an important clinical challenge. | Neal Patel Kian Bichoupan Lawrence Ku Rachana Yalamanchili Alyson Harty Donald Gardenier Michel Ng David Motamed Viktoriya Khaitova Nancy Bach Charissa Chang Priya Grewal Meena Bansal Ritu Agarwal Lawrence Liu Gene Im Jennifer Leong Leona Kim-Schluger Joseph Odin Jawad Ahmad Scott Friedman Douglas Dieterich Thomas Schiano Ponni Perumalswami Andrea Branch | 2016 | World Journal of Gastroenterology2016,22,9: | 1 |
| 13 | Exacerbation of chronic renovascular hypertension and acute renal failure in heine oxygenase-l-deficient mice显示文摘 | Wiesel P Patel AP Carvajal IM etal | 2001 | Circ Res2001,88,10: | 1 |
| 14 | Exacerbation of chronic renovascular hypertension and acute renal failure in heine oxygenase-1-defieient mice 显示文摘 | Wiesel P Patel AP Carvajal IM | 2001 | Circ Res2001,88,10: | 1 |
| 15 | Common variation in the adiponectin gene has an effect on systolic blood pressure 显示文摘 | Avery PJ Patel SK Ibrahim IM | 2011 | J Hum Hypertens2011,25,12: | 1 |
| 16 | Preparation and characterization of proton conducting polysulfone grafted poly(styrenesulfonic acid) polyelectrolyte membranes显示文摘 | Patel R Im S J Ko Y 丁 | 2009 | Journal of Industrial and Engineering Chemistry2009,15,3: | 1 |
| 17 | Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results显示文摘AIM To assess the real-world effectiveness and cost of simeprevir(SMV), and/or sofosbuvir(SOF)-based therapy for chronic hepatitis C virus(HCV) infection.METHODS The real-world performance of patients treated with SMV/SOF ± ribavirin(RBV), SOF/RBV, and SOF/RBV with pegylated-interferon(PEG) were analyzed in a consecutive series of 508 patients with chronic HCV infection treated at a single academic medical center. Patients with genotypes 1 through 4 were included. Rates of sustained virological response-the absence of a detectable serum HCV RNA 12 wk after the end of treatment [sustained virological response(SVR) 12]-were calculated on an intention-to-treat basis. Costs were calculated from the payer's perspective using Medicare/Medicaid fees and Redbook Wholesale Acquisition Costs. Patient-related factors associated with SVR12 were identified using multivariable logistic regression.RESULTS SVR 12 rates were as follows: 86%(95%CI: 80%-91%)among 178 patients on SMV/SOF ± RBV; 62%(95%CI: 55%-68%) among 234 patients on SOF/RBV; and 78%(95%CI: 68%-86%) among 96 patients on SOF/PEG/RBV. Mean costs-per-SVR 12 were $174442(standard deviation: ± $18588) for SMV/SOF ± RBV; $223003(± $77946) for SOF/RBV; and $126496(± $31052) for SOF/PEG/RBV. Among patients on SMV/SOF ± RBV, SVR12 was less likely in patients previously treated with a protease inhibitor [odds ratio(OR): 0.20, 95%CI: 0.06-0.56]. Higher bilirubin(OR: 0.47, 95%CI: 0.30-0.69) reduced the likelihood of SVR12 among patients on SOF/RBV, while FIB-4 score ≥ 3.25 reduced the likelihood of SVR 12(OR: 0.18, 95%CI: 0.05-0.59) among those on SOF/PEG/RBV. CONCLUSION SVR 12 rates for SMV and/or SOF-based regimens in a diverse real-world population are comparable to those in clinical trials. Treatment failure accounts for 27% of costs. | Kian Bichoupan Neeta Tandon James F Crismale Joshua Hartman David Del Bello Neal Patel Sweta Chekuri Alyson Harty Michel Ng Keith M Sigel Meena B Bansal Priya Grewal Charissa Y Chang Jennifer Leong Gene Y Im Lawrence U Liu Joseph A Odin Nancy Bach Scott L Friedman Thomas D Schiano Ponni V Perumalswami Douglas T Dieterich Andrea D Branch | 2017 | World Journal of Virology2017,6,4: | 1 |
| 18 | Main causes of reduced intraocular pressure after excimer laser photorefractive keratectomy显示文摘 | Patel S Aslanides IM | 1996 | J Refract Surg1996,12,6: | 1 |
| 19 | Mutations arg486 and glu571 in human topoisom erase Ilalpha confer resistance to amsacrine relevance for antitumor drug resistance in human cells显示文摘 | Patel S Keller BA Fisher IM | 2000 | Mol Pharmacol2000,57,4: | 1 |
| 20 | Preparation and characterization of proton conducting polyvSulfone grafted poly(styrenesulfonic acid) polyelectrolyte membranes 显示文摘 | Patel R Im S J Ko Y T | 2009 | Journal of Industrial and Engineering Chemistry2009,15,3: | 1 |