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| 1 | Laparoscopic versus open appendectomy: Which way to go?显示文摘AIM: To compare the outcome of laparoscopic versus open appendectomy. METHODS: Prospectively collected data from 293 consecutive patients with acute appendicitis were studied. These comprised of 165 patients who underwent conventional appendectomy and 128 patients treated laparoscopically. The two groups were compared with respect to operative time, length of hospital stay, postoperative pain, complication rate and cost. RESULTS: There were no statistical differences regarding patient characteristics between the two groups. Conversion to laparotomy was necessary in 2 patients (1.5%). Laparoscopic appendectomy was associated with a shorter hospital stay (2.2 d vs 3.1 d, P = 0.04), and lower incidence of wound infection (5.3% vs 12.8%, P = 0.03). However, in patients with complicated disease, intra-abdominal abscess formation was more common after laparoscopic appendectomy (5.3% vs 2.1%, P = 0.002). The operative time and analgesia requirements were similar in the two groups. The cost of treatment was higher by 370 € in the laparoscopic group. CONCLUSION: Laparoscopic appendectomy is as safe and effi cient as open appendectomy, provided surgical experience and equipment are available. | Ioannis Kehagias Stavros Nikolaos Karamanakos Spyros Panagiotopoulos Konstantinos Panagopoulos Fotis Kalfarentzos | 2008 | World Journal of Gastroenterology2008，14，31： | 25 |
| 2 | Parametric optimisation of two Pelton turbine runner designs using CFD显示文摘This paper aims to develop a generic optimisation method for Pelton turbine runners using computational fluid dynamics(CFD). Two different initial runners are optimised to achieve more generic results. A simple bucket geometry based on existing bibliography is parameterised and initially optimised using fast Lagrangian solver(FLS). It is then further optimised with a more accurate method using ANSYS Fluent. The second geometry is a current commercial geometry with good initial performance and is optimised using ANSYS CFX. The analytical results provided by CFX and Fluent simulations are used to analyse the characteristics of the flow for different runner geometries. | IDONIS Audrius PANAGIOTOPOULOS Alexandros AGGIDIS George A. ANAGNOSTOPOULOS John S. PAPANTONIS Dimitris E. | 2015 | Journal of Hydrodynamics2015，27，3： | 6 |
| 3 | Laparoscopic cholecystectomy: A report from a single center显示文摘瞄准:在 laparoscopic 胆囊炎考察并且评估我们的经验。方法:回顾的分析在从经历了 laparoscopic 胆囊炎的 1220 个病人在一个 13 年的时期(1992-2005 ) 期间收集的数据上被执行。结果:死亡率是 0% 。全面患病率是 5.08%(n = 62 ) ,与从损害产生到胆汁的树和膀胱的动脉的最严肃的复杂并发症。在 23 (1.88%) 案例,胆囊炎不能 laparoscopically 被完成,操作被变换成一个开的过程。尽管病人作为天外科案例被安排,医院停留的平均持续时间是 2.29 d,当有延长医院停留的复杂案例在计算被包括。结论:Laparoscopic 胆囊炎是有病人的有利结果的一种安全、最低限度地侵略的技术。 | Konstantinos Vagenas Stavros N Karamanakos Charalambos Spyropoulos Spyros Panagiotopoulos Menelaos Karanikolas Michalis Stavropoulos | 2006 | World Journal of Gastroenterology2006，12，24： | 5 |
| 4 | 有 laparoscopic Habib 4 × radiofrequency 设备的巨大的 exophytic 肝 haemangioma 的 Laparoscopic 切除术显示文摘 Haemangiomas are the most common solitary benign neoplasm of the liver with an incidence ranging from 5% to 20%. Although usually small and asymptomatic, they may reach considerable proportions and rarely give rise to life-threatening complications. Surgical intervention is required for incapacitating symptoms, established complications, and diagnostic uncertainty. The resection of haemangiomas demands meticulous surgical technique, owing to their high vascularity and the concomitant risk of intra-operative haemorrhage. Laparoscopic resection of giant haemangiomas is even more challenging, and has only been reported twice. We here report the case of a giant 10 cm liver haemangioma which was successfully resected laparoscopically using the laparoscopic HabibTM 4×, a bipolar radiofrequency device, without clamping major vessels and with minimal blood loss. Transfusion of blood or blood products was not required. The patient had an uneventful recovery and was asymptomatic at 7-mo follow-up. | Metesh Acharya Nikolaos Panagiotopoulos Premjithlal Bhaskaran Charis Kyriakides Madhava Pai Nagy Habib | 2012 | World Journal of Gastrointestinal Surgery2012，4，8： | 2 |
| 5 | Significance of an additional unenhanced scan in computed tomography angiography of patients with suspected acute aortic syndrome显示文摘AIM To assess potential benefits of an additional unenhanced acquisition in computed tomography angiography(CTA) in patients with suspected acute aortic syndrome(AAS).METHODS A total of 103 aortic CTA(non-electrocardiography-gated, 128 slices) performed due to suspected AAS were retrospectively evaluated for acute aortic dissection(AAD), intramural hematoma(IMH), or penetrating aortic ulcer(PAU). Spiral CTA protocol consisted of an unenhanced acquisition and an arterial phase. If AAS was detected, a venous phase(delay, 90 s) was added. Images were evaluated for the presence and extent of AAD, IMH, PAU, and related complications. The diagnostic benefit of the unenhanced acquisition was evaluated concerning detection of IMH.RESULTS Fifty-six(30% women; mean age, 67 years; median, 68 years) of the screened individuals had AAD or IMH. A triphasic CT scan was conducted in 76.8%(n =43). 56% of the detected AAD were classified as Stanford type A, 44% as Stanford type B. 53.8% of the detected IMH were classified as Stanford type A, 46.2% as Stanford type B. There was no significant difference in the involvement of the ascending aorta between AAD and IMH(P = 1.0) or in the average age between AAD and IMH(P = 0.548), between Stanford type A and Stanford type B in general(P = 0.650) and between Stanford type A and Stanford type B within the entities of AAD and IMH(AAD: P = 0.785; IMH: P = 0.146). Only the unenhanced acquisitions showed a significant density difference between the adjacent lumen and the IMH(P = 0.035). Subadventitial hematoma involving the pulmonary trunk was present in 5 patients(16%) with Stanford A AAD. The difference between the median radiation exposure of a triphasic(2737 mGy*cm) compared to a biphasic CT scan(2135 mGy*cm) was not significant(P = 0.135).CONCLUSION IMH is a common and difficult to detect entity of AAS. An additional unenhanced acquisition within an aortic CTA protocol facilitates the detection of IMH. | Nikolaos Panagiotopoulos Felix Drüschler Martin Simon Florian M Vogt Sebastian Wolfrum Steffen Desch Doreen Richardt Jorg Barkhausen Peter Hunold | 2018 | World Journal of Radiology2018，10，11： | 2 |
| 6 | Long-term results in surgically treated acetabular fractures through the posterior approaches显示文摘 | Triantaphillopoulos PG Panagiotopoulos EC Mousafiris C | 2007 | J Trauma2007，62，2： | 1 |
| 7 | Integrating albu-minuria and GFR in the assessment of diabetic nephropathy 显示文摘 | Jerums G Panagiotopoulos S Premaratne E | 2009 | Na-ture Reviews Nephrology2009，5，7： | 1 |
| 8 | Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis显示文摘 | Jerums George Panagiotopoulos Sianna Premaratne Erosha Power David A Macisaac Richard J | 2008 | American Journal of Nephrology2008，，4： | 1 |
| 9 | Long-term results in surgically treated acetabular fractures through the posterior approaches显示文摘 | Triantaphillopoulos PG Panagiotopoulos EC Mousafiris C el al | 2007 | J Trauma2007，62，2： | 1 |
| 10 | Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease显示文摘 | MACICAAC R J PANAGIOTOPOULOS S MCNEIL K J | 2006 | Diabetes Care2006，29，7： | 1 |
| 11 | Newborn complications after intrapartum asphyxia with metabolic acidosis in the term fetus 显示文摘 | Low JA Panagiotopoulos C Derrick EJ | 1994 | Am J Obstet Gynecol1994，170，： | 1 |
| 12 | Proteolysis of insulin-llke gromh factor-bindlng protein-3 is increased in urine from patients with diabetic nephropathy 显示文摘 | Shinada M Akdeniz A Panagiotopoulos S | 2000 | J Clin Endocrinol Metab2000，85，3： | 1 |
| 13 | Integrating albuminuria and GFR in the assessment of diabetic nephropathy显示文摘 | Jerums G Panagiotopoulos S Premaratne E | | 0，，： | 1 |
| 14 | Low testosterone levels are common and associated with insulin resistance in men with diabetes 显示文摘 | GROSSMANN M THOMAS M C PANAGIOTOPOULOS S | 2008 | J Clin Endocrinol Metab2008，93，5： | 1 |
| 15 | Intralesional 5-fluorouracil in the treatment of keloids:an open clinical and histopathologic study显示文摘 | STEFANAKI C PANAGIOTOPOULOS A | 2005 | J Am Acad Dermatol2005，52，31： | 1 |
| 16 | CoPt:B Granular Thin Films for High Density Magnetic Recording Media显示文摘 | KARANASOS V PANAGIOTOPOULOS I NIARCHOS D | 2001 | J Magn Magn Mater2001，236，： | 1 |
| 17 | Nonalbuminuric renal insufficiency in type 2 diabetes显示文摘 | MACICAAC R J TSALAMANDRIS C PANAGIOTOPOULOS S | 2004 | Diabetes Care2004，27，1： | 1 |
| 18 | The role of pleiotrophin in bone repair显示文摘 | Lamprou M Kaspiris A Panagiotopoulos E | 2014 | Injury2014，45，12： | 1 |
| 19 | Laparo&opy in the emergency setting: a retrospective review of 540 patients with a- cute abdominal pain显示文摘 | Karamanakos S N Sdralis E Panagiotopoulos S | 2010 | Surg Laparesc Endosc Percutan Tech2010，20，2： | 1 |
| 20 | Integrating albuminuria and GFR in the assessment of diabetic nephropathy显示文摘 | JERUMS G PANAGIOTOPOULOS S PREMARATNE E | 2009 | Nat Rev Nephrol2009，5，7： | 1 |
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