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| 1 | Isolated subcutaneous implantation of a borderline ovarian tumor:A case report and review of the literature显示文摘Laparoscopy-related tumor implantations of gynecological malignancies into the subcutaneous tissue are rarely diagnosed.We report an interesting case of a 46-year-old female who presented with an abdominal subcutaneous metastasis of a borderline ovarian tumor.The patient received a laparoscopic unilateral adnexectomy for a solid-cystic tumor of the right ovary.Histopathological workup showed a papillary borderline tumor of mucinous type.Nine days later she underwent a hysterectomy,left adnexectomy,appendectomy and omentectomy.Exploration of the peritoneum revealed no intraperitoneal implants.Further exploration showed a non-invasive implant of a borderline tumor in the subcutaneous tissue above the fascia that had no contact to the peritoneum.It is hypothesized that tumor cells may have been implanted during a previous laparoscopy,the most recent of which had been fourteen years prior to her current presentation.Various risk factors for port-site malignancies have been identified.Tumor manipulation and extraction of tumor tissue without a protective bag may contribute to development of trocarsite metastasis. | Malgorzata Banys-Paluchowski Borsu Yeganeh Jutta Luettges Achim Maibach Ruediger Langenberg Natalia Krawczyk Peter Paluchowski Holger Maul Gerhard Gebauer | 2016 | World Journal of Clinical Oncology2016，7，2： | 4 |
| 2 | CD24 expression is specific for tamoxifen-resistatlt ductal breast cancer cases 显示文摘 | Surowiak P Materna V Paluchowski P | 2006 | Anticancer Res2006，26，1： | 1 |
| 3 | Steroid receptor status,proliferation and metallothionein expression in primary invasive ductal breast cancers显示文摘 | Surowiak P Paluchowski P Wysocka T | 2004 | Pathol Oncol Res2004，10，4： | 1 |
| 4 | CD24 expression is specific for tamoxifen- resistant ductal breast cancer cases 显示文摘 | Surowiak P Matema V Paluchowski P | 2006 | Anticancer Res2006，26，1： | 1 |
| 5 | Liposarcoma of the breast arising in a malignant phyllodes tumor:A case report and review of the literature显示文摘Liposarcoma of the breast is a very rare malignant tumor. It can clinically manifest as a palpable breast mass and mimic primary breast cancer. We report an unusual case of a 51-year-old female who presented with an asymptomatic right breast mass, which was histologically diagnosed as well differentiated liposarcoma arisen within malignant phyllodes tumor. The patient underwent breast conserving surgery, received no adjuvant treatment and is disease-free after 2 years. Radiological and histopathological features are presented and described in detail. Data from the literature are presented and therapy recommendations discussed. | Malgorzata Banys-Paluchowski Eike Burandt Alexander Quaas Waldemar Wilczak Stefan Geist Guido Sauter Natalia Krawczyk Klaus Pietzner Peter Paluchowski | 2015 | World Journal of Clinical Oncology2015，6，5： | 1 |
| 6 | Steroid receptor status,proliferation and metallothionein expression in primary invasive ductal breast cancers显示文摘 | Surowiak P Paluchowski P Wysocka T | | 0，，04： | 1 |
| 7 | Liquid biopsy in metastatic breast cancer显示文摘The spread of single tumor cells shed by the primary tumor has been observed in most solid carcinomas and is generally associated with poor clinical outcome.Tumor cells detected in the peripheral blood are commonly referred to as circulating tumor cells(CTCs)and are seen as possible precursors of metastatic disease.Beyond CTCs,circulating tumor DNA and non-coding RNA are increasingly the focus of translation cancer research.In metastatic breast cancer(MBC),elevated levels of CTCs have been confirmed as an independent prognostic factor.While detection of elevated counts after the start of systemic therapy predicts poor response,it is unclear which treatment strategy should be offered in the case of CTC persistence.Currently,the main potentials of blood-based diagnostics in BC are therapy monitoring and liquid biopsy-based treatment interventions.Recently,the first positive study on CTC-guided therapy choices in hormone receptor positive HER2 negative MBC was published.In the present review,we discuss the current data and potential clinical application of liquid biopsy in the metastatic setting. | Malgorzata Banys-Paluchowski Peter Paluchowski | 2019 | Cancer Drug Resistance2019，2，4： | 0 |
| 8 | Male papillary breast cancer treated by wide resection and latissimus dorsi flap reconstruction: A case report and review of the literature显示文摘Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation. He denied any first- or second degree family medical history of cancer of any type and he never received radiotherapy. Ultrasound guided minimal-invasive 14-gauge core biopsy revealed a moderately differentiated encapsulated papillary carcinoma with high expression of estrogen and progesterone receptors(both > 80%, IRS 12) and HER2-negative. Because of the tumor size a mastectomy with axillary dissection and chest wall reconstruction using a latissimus dorsi flap was performed. Histological analysis showed invasive growth besides typical(non-invasive) papillary carcinoma and was classified as invasive solid papillary carcinoma; p T3(10 cm), p N0(0/15), M0,R0; Oncotype DX Recurrence Score indicated low risk(RS: 2). After discussion in the interdisciplinary tumor board meeting, radiation therapy and tamoxifen were recommended. The patient had an uneventful recovery and is disease-free after two years of follow-up. Male BC is typically diagnosed at an advanced stage, most likely due to a lack of awareness that men can develop BC. Therefore, in case of a large tumor, a flap-based thoracic reconstruction may be required. | Malgorzata Banys-Paluchowski Eike Burandt Joanna Banys Stefan Geist Guido Sauter Natalia Krawczyk Peter Paluchowski | 2016 | World Journal of Clinical Oncology2016，7，5： | 0 |
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