|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Spatial and temporal distributions of nitrogen,phosphorus and heavy metals in the intertidal sediment of the Chang jiang River Estuary in China显示文摘Spatial and temporal distributions of nutrients(N and P) and heavy metals(Cu,Zn,Pb and Cd) in the intertidal sediments at Dongtan wetland of the Changjiang River(Yangtze River) Estuary were examined by laying one transect running seaward to landward during January,April,June,August and October of 2005. Total nitrogen(TN) and heavy metal concentrations in the intertidal sediment showed an increasing trend from open bare flat to the high marsh,with the maximum concentrations in the high marsh and the minimum values in open bare flat. In contrast,sediment total phosphorus(TP) concentrations changed little among sampling sites. One-way ANOVA found that there were significantly temporal variations of nutrients and heavy metals concentrations in the intertidal sediment(P <0.05) . The concentrations of heavy metals generally showed an increasing trend from January to October. As compared with other large estuaries,heavy metal contamination in the intertidal sediment of the Changjiang River Estuary was relatively low. | QUAN Weimin SHI Liyan HAN Jindi PING Xianyin SHEN Anglv CHEN Yaqu | 2010 | Acta Oceanologica Sinica2010，29，1： | 7 |
| 2 | Effects of Bacterial-Feeding Nematodes and Glucose on Phenanthrene Removal by Pseudomonas putida显示文摘Bacterial-feeding nematodes can promote the bacterial activity through feeding.Bacterial abundance and their activity affect the degradation of polycyclic aromatic hydrocarbons(PAH) such as phenanthrene.The effects of bacterial-feeding nematodes,bacteria,and their interactions on the degradation of phenanthrene with or without glucose were studied through a microcosm experiment.The results showed that up to 57.0%of phenanthrene in mineral medium contaminated with phenanthrene was degraded in the control with bacteria alone and bacteria with the presence of nematodes and/or glucose increased the degradation of phenanthrene by 25.6%to 36.6%.Although both nematode and bacteria abundance decreased gradually,catechol 2,3-dioxygenase(C230) activity increased during the incubation period.Compared with bacteria alone,the presence of nematodes significantly increased C230 activity as well as the abundance of bacteria;this effect was more pronounced when glucose was present.The results imply that nematodes might promote the removal of phenanthrene from medium by stimulating bacteria and C230 activities. | JING Yongping LIYan LIU Zhaohui ZHANG Yingpeng LIU Ping SUN Ming Jiafa LUO | 2017 | Pedosphere2017，27，1： | 2 |
| 3 | Cell orientation of swimming bacteria:From theoretical simulation to experimental evaluation显示文摘The motion of small bacteria consists of two phases:relatively long runs alternate with intermittent stops,back-ups,or tumbles,depending on the species.In polar monotrichous bacteria,the flagellum is anchored at the cell pole inherited from the parent generation(old pole) and is surrounded by a chemoreceptor cluster.During forward swimming,the leading pole is always the pole recently formed in cell division(new pole).The flagella of the peritrichous bacterium Escherichia coli often form a bundle behind the old pole.Its cell orientation and receptor positioning during runs generally mimic that of monotrichous bacteria.When encountering a solid surface,peritrichous bacteria exhibit a circular motion with the leading pole dipping downward.Some polar monotrichous bacteria also perform circular motion near solid boundaries,but during back-ups.In this case,the leading pole points upward.Very little is known about behavior near milieu-air interfaces.Biophysical simulations have revealed some of the mechanisms underlying these phenomena,but leave many questions unanswered.Combining biophysics with molecular techniques will certainly advance our understanding of bacterial locomotion. | PING LiYan | 2012 | Science China(Life Sciences)2012，55，3： | 2 |
| 4 | Chinese consensus guidelines for therapeutic drug monitoring of polymyxin B,endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society显示文摘Polymyxin B,which is a last-line antibiotic for extensively drug-resistant Gram-negative bacterial infections,became available in China in Dec.2017.As dose adjustments are based solely on clinical experience of risk toxicity,treatment failure,and emergence of resistance,there is an urgent clinical need to perform therapeutic drug monitoring(TDM)to optimize the use of polymyxin B.It is thus necessary to standardize operating procedures to ensure the accuracy of TDM and provide evidence for their rational use.We report a consensus on TDM guidelines for polymyxin B,as endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society.The consensus panel was composed of clinicians,pharmacists,and microbiologists from different provinces in China and Australia who made recommendations regarding target concentrations,sample collection,reporting,and explanation of TDM results.The guidelines provide the first-ever consensus on conducting TDM of polymyxin B,and are intended to guide optimal clinical use. | XIAOFEN LIU CHENRONG HUANG PHILLIP JBERGEN JIAN LI JINGJING ZHANG YIJIAN CHEN YONGCHUAN CHEN BEINING GUO FUPIN HU JINFANG HU LINLIN HU XIN LI HONGQIANG QIU HUA SHAO TONGWEN SUN YU WANG PING XU JING YANG YONG YANG ZHENWEI YU BIKUI ZHANG HUAIJUN ZHU XIAOCONG ZUO YI ZHANG LIYAN MIAO JING ZHANG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，2： | 1 |
| 5 | Identification of the heat shock protein 70 (HLHsp70) in Haemaphysalis longicornis显示文摘 | Zhancheng Tian Guangyuan Liu Liyan Zhang Hong Yin Hui Wang Junren Xie Ping Zhang Jin Luo | 2011 | Veterinary Parasitology2011，，2： | 1 |
| 6 | Separation of Water from Extra-viscous Oil under Microwave Radiation in the Presence of Inorganic Salts显示文摘Removal of water contained in extra-viscous crude oil is quite difficult because of the high viscosity and high resins content of heavy oil.The microwave technology was introduced for the separation of water from high-viscosity crude oil in the presence of sodium acetate.The decrease in zeta-potential of interface and the viscosity of crude oil are responsible for the accelerated separation of water under microwave irradiation.The influences of the concentration of sodium acetate in sample,irradiation pressure,irradiation time and irradiation power on the separation efficiency were investigated.The optimum technological condition for the refining process was determined.Upon treating the sample 1 (with a water concentration of 50%),the water removal rate was 98.44%,when the optimum conditions were identified to be a sodium acetate concentration of 2%,an irradiation pressure of 0.1 MPa,an irradiation time of 2 min,and an irradiation power of 225 W,with the recovery of sodium acetate reaching 97.88%.Upon treating the sample 2 (the concentration of water was 20%),the water removal rate was 93.85%,when the optimum conditions were determined to be a sodium acetate concentration of 3%,an irradiation pressure of 0.1 MPa,an irradiation time of 4 min,and an irradiation power of 375 W,with the recovery of sodium acetate reaching 93.54%.By using this method,the dehydration efficiency was increased rapidly. | Zhao Shanlin Li Ping Shang Liyan Ma Li | 2011 | China Petroleum Processing & Petrochemical Technology2011，13，3： | 1 |
| 7 | A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response显示文摘The recently emerged severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which is the causative agent of ongoing global pan demic of COVID-19,may trigger imm uno suppression in the early stage and overactive immune resp onse in the late stage of infection;However,the un derlying mecha nisms are not well understood.Here we dem on strated that the SARS-CoV-2 nucleocapsid(N)protein dually regulated innate immune responses,i.e.,the low-dose N protein suppressed type I interferon(IFN-I)signaling and inflammatory cytokines,whereas high-dose N protein promoted IFN-I signaling and inflammatory cytokines.Mechanistically,the SARS-CoV-2 N protein dually regulated the phosphorylation and nuclear translocation of IRF3,STAT1,and STAT2.Additi on ally,low-dose N protein combined with TRIM25 could suppress the ubiquitination and activatio n of retinoic acidinducible gene I(RIG-I).Our findings revealed a regulatory mechanism of innate immune responses by the SARS-CoV-2 N protein,which would contribute to understanding the pathogenesis of SARS-CoV-2 and other SARS-like coronaviruses,and development of more effective strategies for controlling COVID-19. | Yinghua Zhao Liyan Sui Ping Wu Wenfang Wang Zedong Wang Yang Yu Zhijun Hou Guangyun Tan Quan Liu Guoqing Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 1 |
| 8 | Wood identification with PCR targeting noncoding chloroplast DNA 显示文摘 | TANG Xiaoshu ZHAO Guangjie PING Liyan | 2011 | Plant Mol Biol2011，77，6： | 1 |
| 9 | Advanced nano drug delivery systems for neuroprotection against ischemic stroke显示文摘Ischemic stroke(IS)represents a significant threat to brain health due to its elevated mortality and disability rates.The efficacy of small-molecule neuroprotective agents has been impeded by challenges associated with traversing the blood-brain barrier(BBB)and limited bioavailability.Conversely,advanced nano drug delivery systems hold promise for overcoming these obstacles by facilitating efficient transportation across the BBB and maintaining optimal drug concentrations.This review aims to explore advanced neuroprotective nano drug delivery systems as a means of effectively administering neuroprotective agents to the brain using pharmaceutical approaches in the treatment of IS.By examining these systems,researchers and clinicians can gain valuable insights and innovative concepts,illuminating the potential of advanced neuroprotective nano drug delivery systems.Leveraging these advancements can drive the progress of pioneering and efficacious therapeutic interventions for IS. | Chenchen Xie Jun Liao Ning Zhang Yuhan Sun Yi Li Liyan Xiong Yingnan Zhang Xiaoyan Liu Wei Su Heming Chen Ping Zeng Xiaoqing Zhang Ying Lu Tingfang Wang Chuan Zhang | 2024 | Chinese Chemical Letters2024，35，2： | 0 |
| 10 | An Investigation Into the Needs and Challenges of County-Level Family Education Guidance Services and Corresponding Improvement Measures显示文摘The delivery of targeted family education guidance services is essential for establishing a three-in-one education model that encompasses families,schools,and communities.It is also the key to creating a favorable educational environment that promotes the comprehensive and healthy development of individual students.To gain a comprehensive understanding of family education characteristics and trends in Chinese counties,accurately tap into the educational needs of parents,and effectively identify strengths and weaknesses in family education guidance services,this paper employed a quantitative research method based on a questionnaire survey and interview data from J district of C city after years of continuous monitoring of the quality of family education in the area,aiming to explore these issues and put forward several suggestions for improvement.The results indicate that the family learning environment and atmosphere in the district are generally favorable,while parental educational competence requires further improvement.Parents express a strong desire for interactive,systematic,and fragmented family education guidance from schools.Most parents acknowledge the significance of receiving guidance on family education,yet they are disinclined to actively engage in learning-related activities.While the operational mechanisms of county-level family education guidance services have been continuously improved,there is a need for greater overall coordination.Furthermore,the potential of school-led family education guidance services has yet to be fully tapped,and the scientific and professional standards of such guidance need to be further enhanced.Based on the aforementioned findings,we propose recommendations for improvement.Using J district’s effective improvement practices in management,curriculum,and teams as an example,we intend to explore practical ways to promote county-level family education guidance services and provide a valuable reference for the establishment of a comprehensive and effective system to improve such services. | Deng Xiaobing Tian Liyan Ji Ping Yang Wei | 2023 | Contemporary Social Sciences2023，8，3： | 0 |
| 11 | Determining the effects of LFHV-PEF treatment on the water distribution and vigor of aged rice seeds using LF-NMR显示文摘This study aimed to investigate the effect of low-frequency high-voltage pulsed electric field (LFHV-PEF) treatment on the germination of aged rice seeds. Aged rice seeds were subjected to LFHV-PEF treatment with different electric field strengths, and low-field nuclear magnetic resonance (LF-NMR) was performed to acquire the LF-NMR data of rice seeds at different germination periods during a standard seed germination test to analyze their internal patterns of water state and distribution. Optimal treatment conditions were determined based on the physicochemical data collected during germination, and the improvements in seed vigor were verified. The findings indicated that during germination, the contents of bound and semi-bound water within the aged rice seeds initially increased and then decreased, whereas free water and total water contents increased continuously and rapidly. Side peaks were also observed within the seeds. Under the LFHV-PEF treatment, the semi-bound water within the seeds was more easily converted to free water, and the water absorption rate, germination potential, germination rate, germination index, and vigor index of these seeds improved. Further, the optimal electrical field strength was 12 kV. By analyzing the internal patterns of water state and distribution in seeds, the mechanism by which electric field treatment improved seed vigor was elucidated, thus, providing theoretical support and data evidence for research on water absorption during the germination of rice seeds, and methods for improving seed vigor. | Ensi Cheng Ping Song Tiangang Hou Liyan Wu Benhua Zhang | 2022 | International Journal of Agricultural and Biological Engineering2022，15，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员