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| 1 | Hepatic echinococcosis:Clinical and therapeutic aspects显示文摘Echinococcosis or hydatid disease(HD)is a zoonosis caused by the larval stages of taeniid cestodes belonging to the genus Echinococcus.Hepatic echinococcosis is a life-threatening disease,mainly differentiated into alveolar and cystic forms,associated with Echinoccus multilocularis(E.multilocularis)and Echinococcus granulosus(E.granulosus)infection,respectively.Cystic echinococcosis(CE)has a worldwide distribution,while hepatic alveolar echinococcosis(AE)is endemic in the Northern hemisphere,including North America and several Asian and European countries,like France,Germany and Austria.E.granulosus young cysts are spherical,unilocular vesicles,consisting of an internal germinal layer and an outer acellular layer.Cyst expan-sion is associated with a host immune reaction and the subsequent development of a fibrous layer,called the pericyst;old cysts typically present internal septations and daughter cysts.E.multilocularis has a tumorlike,infiltrative behavior,which is responsible for tissue destruction and finally for liver failure.The liver is the main site of HD involvement,for both alveolar and cystic hydatidosis.HD is usually asymptomatic for a long period of time,because cyst growth is commonly slow;the most frequent symptoms are fatigue and abdominal pain.Patients may also present jaundice,hepatomegaly or anaphylaxis,due to cyst leakage or rupture.HD diagnosis is usually accomplished with the combined use of ultrasonography and immunodiagnosis;furthermore,the improvement of surgical techniques,the introduction of minimally invasive treatments[such as puncture,aspiration,injection,re-aspiration(PAIR)]and more effective drugs(such as benzoimidazoles)have deeply changed life expectancy and quality of life of patients with HD.The aim of this article is to provide an up-todate review of biological,diagnostic,clinical and therapeutic aspects of hepatic echinococcosis. | Giuseppe Nunnari Marilia R Pinzone Salvatore Gruttadauria Benedetto M Celesia Giordano Madeddu Giulia Malaguarnera Piero Pavone Alessandro Cappellani Bruno Cacopardo | 2012 | World Journal of Gastroenterology2012，18，13： | 72 |
| 2 | Immunology and immunotherapy of colorectal cancer显示文摘 | Piero D Cristina M Chiara C | 2003 | Crit Rev Oncol/Hematol2003，46，1： | 2 |
| 3 | The role of transthoracic echocardiography in the diagnosis and management of acute type A aortic syndrome显示文摘 | Moreno Cecconi Fabio Chirillo Carlo Costantini Gianfranco Iacobone Ercole Lopez Raffaele Zanoli Alberto Gili Stefano Moretti Marcello Manfrin Christopher Münch Lucia Torracca Gian Piero Perna | 2012 | American Heart Journal2012，，1： | 2 |
| 4 | CT angiography in acute ischemic stroke:preliminary results显示文摘 | Piero V Lawrence N T Neil M B | 2002 | Stroke2002，33，： | 1 |
| 5 | Industrial clusters,knowledge integration and per formance显示文摘 | PIERO M | 2004 | World Development2004，32，2： | 1 |
| 6 | C-reacive Protein and interleukin-6 leveld are related to renal function in predialytic chronic renal failure显示文摘 | Panichi V Migliori M De Piero S | 2002 | Nephron2002，91，4： | 1 |
| 7 | New developments in the study of ancient pottery by colour measurement 显示文摘 | Piero M Patrizia D | 2004 | Archaeol Sci2004，，31： | 1 |
| 8 | Missing OH reactivity in a forest : evidence for unknown reactive biogenic VOCs 显示文摘 | Piero D C William H B Monica M | 2004 | Science2004，304，5671： | 1 |
| 9 | Effects of ocean acidification and elevated temperature on shell plasticity and its energetic basis in an intertidal gastropod显示文摘 | SEDERCOR M PIERO C SIMON R | 2013 | Marine Ecology Progress Series2013，472，： | 1 |
| 10 | Psychological treatment of eating disorders, review of the literature 显示文摘 | Fassino S Piero A Levi M | 2004 | Panminerva Med2004，46，3： | 1 |
| 11 | Industrial Clusters, Knowledge Integration and Performance 显示文摘 | Piero M | 2004 | World Development2004，32，2： | 1 |
| 12 | Proteinuria predicts end stage renal failure in non diabetic chronic nephropathies显示文摘 | Piero R Annalisa P Lidia M | 1997 | Kidney Int1997，52，63： | 1 |
| 13 | Bromocriptine and speech therapy in non-fluent chronic aphasia after stroke 显示文摘 | BRAGONI M ALTIERI M DI PIERO V | 2000 | Neurol Sci2000，21，1： | 1 |
| 14 | Short-and long-term effects of early fosinopril administration in patients with acute anterior MI undergoing intravenous thrombolysis:Results from the Fosiopril in AMI Study显示文摘 | Claudio B Paoolo M Piero Z | 1998 | Am Heart J1998，136，： | 1 |
| 15 | Environmental cDNA analysis of the genes involved in lignocellulose digestion in the symbiotic protist community of Reticulitermes speratus 显示文摘 | Todaka N Moriya S Saita K Hondo T Kiuchi I Takasu H Ohkuma M Piero C Hayashizaki Y Kudo T | 2007 | FEMS Microbiol Ecol2007，59，3： | 1 |
| 16 | Pancreatic islets from type 2 diabetes patients have functional defects and increased apoptosis that are ameliorated by metformin显示文摘 | PIERO MARCHETTI SILVIA D G LORELLA M etal | 2004 | J Clin Endocrinol2004，89，： | 1 |
| 17 | Cellular and structural bases of chronic obstructive pulmonary disease 显示文摘 | Marina S Graziella T Piero M | 2001 | Am J Respir Crit Care Med2001，163，6： | 1 |
| 18 | Behaviour of calcium-based sorbents towards SO2 capture in a high pressure thermobalance显示文摘 | CARUGATI A DEL PIERO G | 1992 | Fuel1992，71，8： | 1 |
| 19 | Sjogren's syndrome presenting as ischemic stroke显示文摘 | Bragoni M Di Piero V Priori R | 1994 | Stroke1994，25，： | 1 |
| 20 | Editor’s choice: Carotid intima-media thickness by B-mode ultrasound as surrogate of coronaryatherosclerosis : correlation with quantitative coronary anyiographyand coronary intravascular ultrasound findings 显示文摘 | Mauro A Piero M Alessio R | 2007 | Eur Heart J2007，28，17： | 1 |
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