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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | Stability and vibration of isotropic,orthotropic and laminated plates according a higher-order shear deformation theory显示文摘 | REDDY J PHAN N D | 1985 | Journal of Sound and Vibration1985，98，2： | 1 |
| 3 | Safety of total thyroidectomy显示文摘 | Serpell JW Phan D | 2007 | ANZ J Surg2007，77，12： | 1 |
| 4 | S3: A Spectral and Spatial Measure of Local Perceived Sharpness in Natural Images显示文摘 | Vu C Phan T Chandler D | 2012 | IEEE Transactions on Image Processing2012，21，3： | 1 |
| 5 | 查看详情显示文摘 | Fick J Soderstrom H Linberg R H Phan C Tvsklind M Larsson D G J | | 0，，12： | 1 |
| 6 | Safety of total thyroidectomy显示文摘 | Serpell JW Phan D | 2007 | ANZ J Surg2007，77，12： | 1 |
| 7 | Two-dimensional simulation of cement hydration显示文摘 | PHAN QUOC H D TAKETO U | 1999 | Transactions of the Japan Concrete Institute1999，21，1： | 1 |
| 8 | Safety of total thyroidectomy显示文摘 | SERPELL J W PHAN D | 2007 | ANZJ Surg2007，77，： | 1 |
| 9 | BOP,a regulater of right ventricular heart development,is a direct transcriptional target of MEF2C in the developing heart显示文摘 | Phan D Rasmussen TL Nakagawa O | 2005 | Development2005，132，11： | 1 |
| 10 | Energy partitioning into growth,respiration,excretion and exuvia during larvl development of the shrimp Farfantepenaeus paulensis 显示文摘 | Lemos D Phan V N | 2001 | Aquaculture2001，199，： | 1 |
| 11 | Safety of total thyroidectomy显示文摘 | Serpell JW Phan D | 2007 | ANZ J Surg2007，77，12： | 1 |
| 12 | Stability and vibration of isotropic and laminated plates according to a higherorder shear deformation theory显示文摘 | Reddy J N Phan N D | 1985 | Journal of Sound and Vibration1985，98，2： | 1 |
| 13 | Biological variability of sperm DNA denaturation in infertile men显示文摘 | Zini A Kamal K Phan D et a l | 2001 | Urology2001，58，2： | 1 |
| 14 | Effect of extendedsurfactant structure on interfacial tension and microemulsionformation with triglycerides 显示文摘 | Phan T T Attaphong C Sabatini D A | 2011 | Journal of the American OilChemists Society2011，88，8： | 1 |
| 15 | Identification of Sp2 as a transcriptional repressor of carcinoembryonic antigen-related cell adhesion molecule 1 in tumorigenesis 显示文摘 | Phan D Cheng CJ Galfione M | 2004 | Cancer Res2004，64，9： | 1 |
| 16 | In situ detection of collisionless reconnection in the Earth's magnetotail显示文摘 | φIEROSET M PHAN T D FUJIMOTO M | 2001 | Nature2001，412，： | 1 |
| 17 | Safety of total thyroidectomy显示文摘 | SerpellJW Phan D | 2007 | ANZJ Surg2007，77，112： | 1 |
| 18 | Ontology, a Mediator for A gent-Based Modeling in Social Science显示文摘 | Livet P Mtiller J-P Phan D | 2010 | Journal of Artificial Societies and Social Simulation2010，，： | 1 |
| 19 | Switchable Solvents Con- sisting of Amidine/Alcohol or Guanidine/Alcohol Mixtures显示文摘 | L Phan D Chiu D J Heldebrant | 2008 | In- dustrial & Engineering Chemistry Research2008，47，3： | 1 |
| 20 | Entrepreneurship and university based technology transfer显示文摘 | Markman G Phan H Balkin D | 2005 | Journal of Business Venturing2005，，20： | 1 |
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