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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 2 | 适应辐射类群穇属的系统学研究进展显示文摘综合花序拓扑学、比较形态学、分子系统发育、细胞遗传学等资料,对适应辐射类群穇属(Eleusine Gaertn.)的系统学研究进展进行了述评。穇属系统位置——Eleusiinae亚族成员得到分子系统发育证据的支持。该属具有3种花序类型、7个基因组类型、多倍体均由二倍体杂交起源、C4植物高度适应半湿润-半干旱镶嵌气候等特征。据可靠化石记载和现代地理分布推断,穇属很可能起源于东非,时间是晚中新世,而适应辐射则发生在上新世-中新世间隔。总的来说,分子系统发育、细胞遗传学、古地质、古气候数据的整合研究能够为穇属多倍体起源和谱系多样化历史提供令人信服的证据。 | 刘青 PETERSON M Paul | 2010 | 热带亚热带植物学报2010,18,3: | 4 |
| 3 | Interprofessional, multiple step simulation course improves pediatric resident and nursing staff management of pediatric patients with diabetic ketoacidosis显示文摘AIM To investigate the use of a multidisciplinary, longitudinal simulation to educate pediatric residents and nurses on management of pediatric diabetic ketoacidosis.METHODS A multidisciplinary, multiple step simulation course was developed by faculty and staff using a modified Delphi method from the Pediatric Simulation Center and pediatric endocrinology department. Effectiveness of the simulation for the residents was measured with a pre- and post-test and a reference group not exposed to simulation. A follow up post-test was completed 3-6 mo after the simulation. Nurses completed a survey regarding the education activity. RESULTS Pediatric and medicine-pediatric residents(n = 20) and pediatric nurses(n = 25) completed the simulation course. Graduating residents(n = 16) were used as reference group. Pretest results were similar in the control and intervention group(74% ± 10% vs 76% ± 15%, P = 0.658). After completing the intervention, participants improved in the immediate post-test in comparison to themselves and the control group(84% ± 12% post study; P < 0.05). The 3-6 mo follow up post-test results demonstrated knowledge decay when compared to their immediate post-test results(78% ± 14%, P = 0.761). Residents and nurses felt the interdisciplinary and longitudinal nature of the simulation helped with learning.CONCLUSION Results suggest a multidisciplinary, longitudinal simulation improves immediate post-intervention knowledge but important knowledge decay occurs, future studies are needed to determine ways to decrease this decay. | Linnea M Larson-Williams Amber Q Youngblood Dawn Taylor Peterson J Lynn Zinkan Marjorie L White Hussein Abdul-Latif Leen Matalka Stephen N Epps Nancy M Tofil | 2016 | World Journal of Critical Care Medicine2016,5,4: | 4 |
| 4 | 稳定性冠状动脉疾病患者的尿11-脱氢血栓素B_2与死亡率的关系显示文摘已有研究证明,应用阿司匹林抗血小板治疗可减少冠状动脉疾病(coronary artery disease,CAD)患者的不良预后。阿司匹林不可逆地抑制血小板环加氧酶1(cyclooxygenase-1,COX-1)并减弱血栓烷A2(thromboxane A2,TXA2)介导的血小板聚集, | 刘莉 叶鹏 McCullough PA Vasudevan A Sathyamoorthy M Schussler JM Velasco CE Lopez LR Swift C Peterson M Bennett-Firmin J Schiffmann R Bottiglieri T | 2017 | 中华高血压杂志2017,25,1: | 3 |
| 5 | Improvements to NOAA’s Historical Merged Land-Ocean Surface Temperature Analysis (1880-2006)显示文摘 | Smith Thomas M Reynolds Richard W Peterson Thomas C Lawrimore Jay | | Journal of Climate0,,: | 3 |
| 6 | Preoperative magnetic resonance Imaging screening for a surgical decision regarding the approach for anterior spine fusion at the clervicothoracic junction显示文摘 | Fraser J F Diwan A D Peterson M | 2002 | SPINE2002,27,7: | 2 |
| 7 | Rotational relaxation measurements of laser excited Hydrogen fluoride显示文摘 | Peterson L M Lindgulst G H Arnold C B | 1974 | J Chem Phys1974,61,8: | 2 |
| 8 | Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus meduUa显示文摘 | HEINO M PETERSON P KUDOH J | 1999 | Biochemical and Biophysical Research Communications1999,257,: | 1 |
| 9 | RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse显示文摘 | HEINO M PETERSON P SILLANPAA N | 2000 | Eur J Immunol2000,30,: | 1 |
| 10 | Rhinocerebral mucormycosis: evolution of the disease and treatment options显示文摘 | PETERSON K L WANG M CANALIS R F | 1997 | Laryngoscope1997,107,: | 1 |
| 11 | Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction 显示文摘 | STONE G W PETERSON M A LANSKY A J | 2002 | J Am Coll Cardiol2002,39,: | 1 |
| 12 | DERTOR is an roTOR inhibitor frequently overexpressed in multiple myeloma cells and re- quired for their survival显示文摘 | Peterson TR Laplante M Thoreen CC | 2009 | Cell2009,137,5: | 1 |
| 13 | Chromium supplementation for women with gestational diabetes 显示文摘 | Jovanovic L Gutierrez M Peterson CM | 1999 | J Trace Elem Exptl Med1999,12,1: | 1 |
| 14 | Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction显示文摘 | STONE G W PETERSON M A LANSKY A J | 2002 | J Am Coll Cardiol2002,39,: | 1 |
| 15 | On the Implementation of the Frequency-Domain LMS Adaptive Filter显示文摘 | Ogunfunmi A O Peterson A M | 1992 | Analog and Digital Signal Processing IEEE Transactions on1992,39,5: | 1 |
| 16 | On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion显示文摘 | Liu M Liu S Peterson SL | 2002 | Mol Cell Biochem2002,,12: | 1 |
| 17 | The seedling establishment of rice under water in relating to temperature and dissolved oxygen显示文摘 | Chapman A L Peterson M L | 1962 | Crop Sci1962,2,: | 1 |
| 18 | The roles of claudin superfamily proteins in paracellular transport显示文摘 | Heiskala M Peterson PA Yang Y | 2001 | Traffic2001,2,2: | 1 |
| 19 | Extrahepatic metastases of hepatocellular carcinoma 显示文摘 | Katyal S Oliver J H Peterson M S | 2000 | Radiology2000,216,3: | 1 |
| 20 | Vitamin E and donepezil for the treatment of mild cognitive impairment 显示文摘 | Peterson RC Thomas RG Grundman M | 2005 | N Engl J Med2005,352,23: | 1 |