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| 1 | D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation显示文摘AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient. | Jeffrey B Halldorson Robert L Carithers Jr Renuka Bhattacharya Ramasamy Bakthavatsalam Iris W Liou Andre A Dick Jorge D Reyes James D Perkins | 2014 | World Journal of Transplantation2014，4，3： | 2 |
| 2 | Determintion of melamine in pet food by enzyme immunoassay, high- performance liquid chromatography with diode array detection, and ultra-performance liquid chromatography with tandem mass spectrometry显示文摘 | KIM B PERKINS L B BUSHWAY R J | 2008 | J AOAC Int2008，91，： | 1 |
| 3 | Sediment phosphorus cycling in a large shallow lake: spatio-temporal variation phosphorus pools and release显示文摘 | Spears B M Carvalho L Perkins R | 2007 | Hydrobiologia2007，584，1： | 1 |
| 4 | The role of two plant-derived volatiles in the foraging movement of 1stinstar Helicoverpa armigera (Hiibner) :time to stop and smell the flowers 显示文摘 | Perkins L E Cribb B W Hanan J | 2009 | Arthropod-Plant Interactions2009，3，3： | 1 |
| 5 | Reduction in photosynthetic efficiency of Cladophora glomerata, induced by overlying canopies of Lemna spp显示文摘 | Parr L B Perkins R G Mason C F | 1987 | Water Research [Water Res]1987，114，23： | 1 |
| 6 | Paelitaxel-Induced Apoptosis and Mitotic Arrest Assessed by Serial Fine-Needle Aspiration : Implications for Early Prediction of Breast Cancer Response to Neoadjuvant Treatment 显示文摘 | SYMMANS W F VOLM M D SHAPIRO R L PERKINS A B KIM A Y DEMARIA S YEE H T MCMULLEN H ORATZ R KLEIN P FORMENTI S C MUGGIA F | 2000 | Clin Cancer Res2000，6，12： | 1 |
| 7 | Identification and characterization of transcripts from the biotin biosynthetic operon Bacillus subtilis显示文摘 | Perkins J B BowerS Howitt C L | 1996 | Journal of Bacteriology1996，，： | 1 |
| 8 | Detection and confinnation of reptilian adenovirus infection by in situ hybridization 显示文摘 | PERKINS E L CAMPAGNOLI R P HARMON B G | 2001 | Journal of Veterinary Diagnostic Investigation2001，13，： | 1 |
| 9 | Deter- mination of melamine in pet food by enzymeimmunoassay, high-performance liquid chromatographywith diode array detection, and ultra-performance liquidchromatography with tandem mass spectrometry显示文摘 | KIM B PERKINS L B BUSHWAY R J | 2008 | J AOAC Int2008，91，2： | 1 |
| 10 | Determination of melamine in pet food by enzyme imrnunoassay high-performance liquid chromatography with diode array detection, and ultra-performance liquid chromatog- raphy with tandem mass apectrometry 显示文摘 | KIM B PERKINS L B BUSHAW R J | 2008 | JAOAC Int2008，91，2： | 1 |
| 11 | Comparison of visual inspection and Papanicolau (PAP) smears for cervical cancer screening in Honduras:should PAP smears be abandoned?显示文摘 | PERKINS R B LANGRISH S M STERN L J | 2007 | Trop Med Int Health2007，12，9： | 1 |
| 12 | Low-molecular- weight heparin in women with gynecologic malignancy 显示文摘 | DeBemardo R L Jr Perkins R B Littell R D | 2005 | Obstel Gyneco12005，105，51： | 1 |
| 13 | Independence in assisted living显示文摘 | Ball M M Perkins M M Whittington F J Hollingsworth C King S V Combs B L | 2004 | Journal of Aging Studies2004，18，： | 1 |
| 14 | Microalbuminuria and the risk for early progressive renal function decline in type 1 diabe- tes显示文摘 | Perkins B Ficociello L Ostrander B | 2007 | J Am Soc Nephrol2007，，18： | 1 |
| 15 | Determination of melamine in pet food by enzyme immunoassay, high-performance liquid chromatography with ddiode array detection, and ultra-performance liquid chromatography with tandem mass spectrometry显示文摘 | KIM B PERKINS L B BUSHWAY R J | 2008 | Journal of AOAC International2008，91，2： | 1 |
| 16 | Sediment phosphorus cyclingin a large shallow lake: Spatio-temporal variation in phosphorus poolsand release显示文摘 | Spears B M Carvalho L Perkins R | 2007 | Hydrobiologia^2007，584，： | 1 |
| 17 | Plant-Induced Changes in Soil Nutrient Dynamics by Native and Invasive Grass Species显示文摘 | PERKINS L B JOHNSON D W NOWAK R S | 2011 | Plant and Soil2011，345，1： | 1 |
| 18 | Tuning of peroxiredoxin catalysis for various physiological roles 显示文摘 | Perkins A Poole L B Karplus P A | 2014 | Biochemistry2014，53，49： | 1 |
| 19 | ,Cloning and Characterization of the Mete Gene Encoding 5-adenosylmethionrae Synthetase from Bacillus Subtilis显示文摘 | Yocum R R Perkins J B Howitt C L | 1996 | Journal of Bacteriology1996，178，： | 1 |
| 20 | the asymmetric Shi Zihui, Shen michael addition on Hao unsaturated aldehydes Diarylprolinol sil water显示文摘 | Zheng Zilong Perkins B L Ni B | 2010 | J Am yl ether salts as new efficient water-soluble and recyclable organocatalysts for Chem Soc2010，132，1： | 1 |
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