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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Volatile composition and descriptive sensory analysis of pomegranate juice and wine显示文摘 | Antonio J.Andreu-Sevillaa Pedro M Nuria M Cristina G V | | 0，，54： | 1 |
| 3 | High DHA content in Artemiais ineffective to improve Octopus vulgaris paralarvae rearing 显示文摘 | Pedro S Manuel R M Lulsa M P V | 2010 | Aquaculture2010，300，： | 1 |
| 4 | Characterization ofN-trimethyl chitosardalginate complexes andcurcumin release显示文摘 | Martins Alessandro F Bueno Pedro V A Almeida Elizangela A M S | 2013 | International Journal of Biological Macromolecules2013，57，： | 1 |
| 5 | An expeditious method for the determination of organochlorine pesticides residues in estuarine sediments using microwave assisted pre-extraction and automated headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry 显示文摘 | Pedro N C Pedro N R Filipe A Rafael E Maria C P Teresa M V | 2008 | Talanta2008，76，5： | 1 |
| 6 | Cobalt as internal standard for arsenic and selenium determination in urine by simultaneous atomic absorption spectrometry显示文摘 | PAULO R M CORREIA PEDRO V OLIVEIRA | 2005 | Talanta2005，，67： | 1 |
| 7 | Synthesis of black ceramic pig- ments from secondary raw materials 显示文摘 | Costa G Della V P Ribeiro M J De Oliverira Antonio Pedro Novaes Monros Tomas Guillermo Labrineha Batista Joao Antonio | 2008 | Dyes and Pig- ments2008，，77： | 1 |
| 8 | Expectations for the university in the Knowledge-based Economy 显示文摘 | Manuel V Heitor Pedro M Oliveira | 1998 | Technological Forecasting and Social Change1998，58，： | 1 |
| 9 | Denitrogenation of middle distillates using adsorbent materials towards ULSD production: a review显示文摘 | Georgina L Pedro V M Fernando T Z | 2013 | Fuel Processing Technology2013，106，： | 1 |
| 10 | 2-ANTBAL: an ant colony optimization algorithm for balancing two-sided assembly lines 显示文摘 | ANA S S PEDRO M V | 2009 | Computer & Industrial Engineering2009，56，2： | 1 |
| 11 | Performance of a final hydrogen peroxide stage in the ECF bleaching of eucalypt DOEOPD1 kraft pulps 显示文摘 | M Graca V S Carvalho Nuno M V Carvalho Pedro E G Loureuro | 2008 | Tappi Journal2008，7，8： | 1 |
| 12 | Spermatogonial stem cells: characteristics and experimental possibilities显示文摘 | Pedro M A Maaike A V Dirk D R | 2005 | APMIS2005，113，： | 1 |
| 13 | Anomaly detetion me-thods in wired networks:A survey and taxonomy显示文摘 | Pedro G T Jesus E D V | 2004 | Computer Communications2004，27，16： | 1 |
| 14 | Expectations for the university in the Knowledge-based Economy显示文摘 | Pedro Coneeicao Manuel V Heitor Pedro M Oliveira | 1998 | Technological Forecasting and Social Change1998，58，： | 1 |
| 15 | Wind field reproduction using neural networks and conditional simulation显示文摘 | PEDRO M V NEFTALI R C | 2007 | Eng Struct2007，29，7： | 1 |
| 16 | UV-C treatment delays postharvest senescence in broccoli florets显示文摘 | Lorenza C Ariel R V Pedro M C | 2006 | Postharvest Biology and Technology2006，39，2： | 1 |
| 17 | 查看详情显示文摘 | Jorge F J Coelho Fonseca A C Gois J R Goncalves Pedro MOF Popovc Anatoliy V Gil M H | | 0，，： | 1 |
| 18 | Herbal infusions bioelectrochemical polyphenolic index:green tea-the gallic acid in- terference显示文摘 | Dulce M A G Pedro L V F Maria L M S | 2011 | Food Chem2011，129，4： | 1 |
| 19 | Glottal source biometricalsignature for voice pathology detection显示文摘 | PEDRO G V ROBERTO F B VICTORIA R B VICTOR N L AGUSTIN A M LUIS M M F RAFAEL M O JUAN I G L | 2009 | Speech Communication2009，51，9： | 1 |
| 20 | Modeling high-efficiency quantum dot sensitized solar cells显示文摘 | Pedro V G XuX Q SeróI M | | 0，，10： | 1 |
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