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	题名	作者	年代	出处	被引量
1	Insights into platinum-induced peripheral neuropathy–current perspective显示文摘Cancer is a global health problem that is often successfully addressed by therapy, with cancer survivors increasing in numbers and living longer world around. Although new cancer treatment options are continuously explored, platinum based chemotherapy agents remain in use due to their efficiency and availability. Unfortunately, all cancer therapies affect normal tissues as well as cancer, and more than 40 specific side effects of platinum based drugs documented so far decrease the quality of life of cancer survivors. Chemotherapy-induced peripheral neuropathy is a frequent side effects of platinum-based chemotherapy agents. This cluster of complications is often so debilitating that patients occasionally have to discontinue the therapy. Sensory neurons of dorsal root ganglia are at the core of chemotherapy-induced peripheral neuropathy symptoms. In these postmitotic cells, DNA damage caused by platinum chemotherapy interferes with normal functioning. Accumulation of DNA-platinum adducts correlates with neurotoxic severity and development of sensation of pain. While biochemistry of DNA-platinum adducts is the same in all cell types, molecular mechanisms affected by DNA-platinum adducts are different in cancer cells and non-dividing cells. This review aims to raise awareness about platinum associated chemotherapy-induced peripheral neuropathy as a medical problem that has remained unexplained for decades. We emphasize the complexity of this condition both from clinical and mechanistical point of view and focus on recent findings about chemotherapy-induced peripheral neuropathy in in vitro and in vivo model systems. Finally, we summarize current perspectives about clinical approaches for chemotherapy-induced peripheral neuropathy treatment.	Andrijana Lazić Jelena Popović Tatjana Paunesku Gayle EWoloschak Milena Stevanović	2020	Neural Regeneration Research2020，15，9：	2
2	Duetal carcinoma in situ: X-ray floureseenee microscopy and dynamic con- trast-enhanced MR imaging reveals gadolinium uptake within neoplastic mammary duets in a murine model 显示文摘	Jansen SA Paunesku T Fan X	2009	Radiology2009，253，2：	1
3	Proliferating cell nuclear antigen (PCNA): ringmaster of the genome显示文摘	Paunesku S Mittal hi	2001	Int J Radiat Biol2001，77，10：	1
4	Deficient PCNA expression and radiation sensitivity 显示文摘	Woloschak GE Paunesku T	2002	International Congress Series2002，12，36：	1
5	Proliferating cell nuclear antigen (PCNA): ringmaster of the genome 显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
6	Biology of TiO2-DNA oligonucleotide nanocomposites显示文摘	Paunesku T Rajh T Wiederrecht G	2003	Nat Mater2003，2，2：	1
7	Proliferating cell nuclear antigen (PCNA):ringmaster of the genome显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
8	Sensitivity to low-level radiation in radiosensitive 'wasted' mice 显示文摘	Woloschak GE Paunesku T Protic M	2002	Mil Med2002，167，2：	1
9	Proliferating cell nuclear antigen (PCNA):ringmaster of the genome显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
10	Proliferating cell nuclear antigen (PCNA):ringmaster of the genome显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
11	Proliferatingcell nuclear antigen (PCNA):ringmaster of the genome显示文摘	PAUNESKU T MITTAL S PROTI M	2001	Int J Radiat Biol2001，77，10：	1
12	Proliferating cell nuclear antigen(PCNA):riognaster of the genome显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
13	Uptake and distribution of ultra small anatase TiO: alizarin red S nanoconjugates in Arabidopsisthaliana 显示文摘	Kurepa J Paunesku T Vog S	2010	Nano Letters2010，10，7：	1
14	查看详情显示文摘	Paunesku T		0，，6：	1
15	Proliferating cell nuclear antigen (PCNA): ringmaster of the genome 显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1
16	Uptake and distribution of ultrasmall anatase TiO2 Alizarin red S nanoconjugates in Arabidopsis thaliana显示文摘	Kurepa J Paunesku T Vogt S	2010	Nano Lett2010，10，7：	1
17	Uptake and distribution of ultrasmall anatase TiO2 alizarin red S nanoconjugates in Arabidopsis thaliana显示文摘	Kurepa J Paunesku T Vogt S		0，，07：	1
18	Uptake and distribution of ultrasmall anatase TiO2 alizarin red S nanoconiugates in arabidopsis thaliana显示文摘	Kurepa J Paunesku T Vogt S Arora H Rabatic B M Lu J	2010	Nano Lett2010，10，：	1
19	Response of heteroge-neous ribonuclear proteins(hnRNP) to ionising radiation and their involvement in DNA damage repair显示文摘	HALEY B PAUNESKU T PROTIC M		0，，08：	1
20	Proliferating cell nuclear antigen (PCNA) : ringmaster of the genome 显示文摘	Paunesku T Mittal S Protic M	2001	Int J Radiat Biol2001，77，10：	1

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