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| 1 | Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis显示文摘AIM: To determine the clinical impact of portal vein thrombosis in terms of both mortality and hepatic decompensations(variceal hemorrhage, ascites, portosystemic encephalopathy) in adult patients with cirrhosis.METHODS: We identified original articles reported through February 2015 in MEDLINE, Scopus, Science Citation Index, AMED, the Cochrane Library, and relevant examples available in the grey literature. Two independent reviewers screened all citations for inclusion criteria and extracted summary data. Random effects odds ratios were calculated to obtain aggregate estimates of effect size across included studies, with 95%CI.RESULTS: A total of 226 citations were identified and reviewed, and 3 studies with 2436 participants were included in the meta-analysis of summary effect. Patients with portal vein thrombosis had an increased risk of mortality(OR = 1.62, 95%CI: 1.11-2.36, P = 0.01). Portal vein thrombosis was associated with an increased risk of ascites(OR = 2.52, 95%CI: 1.63-3.89, P < 0.001). There was insufficient data available to determine the pooled effect on other markers of decompensation including gastroesophageal variceal bleeding or hepatic encephalopathy. CONCLUSION: Portal vein thrombosis appears to increase mortality and ascites, however, the relatively small number of included studies limits more generalizable conclusions. More trials with a direct comparison group are needed. | Jonathan G Stine Puja M Shah Scott L Cornella Sean R Rudnick Marwan S Ghabril George J Stukenborg Patrick G Northup | 2015 | World Journal of Hepatology2015，7，27： | 42 |
| 2 | Hepatocellular carcinoma surveillance:An evidence-based approach显示文摘Hepatocellular carcinoma(HCC) makes up 75%-85% of all primary liver cancers and is the fourth most common cause of cancer related death worldwide. Chronic liver disease is the most significant risk factor for HCC with 80%-90% of new cases occurring in the background of cirrhosis. Studies have shown that early diagnosis of HCC through surveillance programs improve prognosis and availability of curative therapies. All patients with cirrhosis and high-risk hepatitis B patients are at risk for HCC and should undergo surveillance. The recommended surveillance modality is abdominal ultrasound(US) given that it is cost effective and noninvasive with good sensitivity. However, US is limited in obese patients and those with non-alcoholic fatty liver disease(NAFLD). With the current obesity epidemic and rise in the prevalence of NAFLD, abdominal computed tomography or magnetic resonance imaging may be indicated as the primary screening modality in these patients. The addition of alpha-fetoprotein to a surveillance regimen is thought to improve the sensitivity of HCC detection.Further investigation of serum biomarkers is needed. Semiannual screening is the suggested surveillance interval. Surveillance for HCC is underutilized and low adherence disproportionately affects certain demographics such as nonCaucasian race and low socioeconomic status. | Patrick S Harris Ross M Hansen Meagan E Gray Omar I Massoud Brendan M McGuire Mohamed G Shoreibah | 2019 | World Journal of Gastroenterology2019，25，13： | 31 |
| 3 | Silver doped titanium dioxide nanomaterials for enhanced visible light photocatalysis显示文摘 | K S Michael G Reenamole F Patrick | 2007 | Journal of Photochemistry and Photobiology A2007，189，： | 1 |
| 4 | Near infrared spectroscopy in patient with sever brain injury and elevated ICP:a pilot study显示文摘 | Melville S Mark G | 1997 | Acta Neurochir Suppl(wien)1997，70，1： | 1 |
| 5 | Vaccination of chronic hepatitis B virus carriers with preS2/S envelope protein is not associated with the emergence of envelope escape mutants显示文摘 | PATRICK S STANISLAS P FLORIANNE G | 2001 | J Gen Virol2001，82，： | 1 |
| 6 | 查看详情显示文摘 | Schuch R Garibian A Nygaard P Raymond S Araik G Hans H S Patrick J P Per N | | 0，，： | 1 |
| 7 | Adaptive wavelet transform for vibration signal modeling and application in fault diagnosis of water hydraulic motor 显示文摘 | Chen H X Patrick S K Chua G H L | 2006 | Mechanical Systems and Signal Processing2006，，20： | 1 |
| 8 | Multiple independent emer- gences of type 2 vaccine-derived polioviruses during a large outbreak in northern Nigeria显示文摘 | Burns C C Shaw J Jorba J Bukbuk D Adu F Gumede N Pate M A Abanida E A Gasasira A Iber J Chen Q Vincent A Chenoweth P Henderson E Wannemuehler K Naeem A Umarni R N Nishimura Y Shimizu H Baba M Adeniji A Williams A J Kil- patrick D R Oberste M S Wassilak S G Tomori O Pallansch M A Kew O | 2013 | J Virol2013，87，9： | 1 |
| 9 | Structure and mechanics of the squid mantle 显示文摘 | Patrick M S Erik A G | 1999 | The Journal of Experimental Biology1999，，202： | 1 |
| 10 | A short synthesis of (±) -epiasarinin 显示文摘 | David J A Anne J D Patrick G S | 2002 | Organic Letters2002，7，4： | 1 |
| 11 | An optimized quality control procedure for hematology analyzers with the use of retained patient specimens显示文摘 | Cembrowski G S Lunetzky E S Patrick C C | 1988 | Am J Clin Pathol1988，89，2： | 1 |
| 12 | Silver doped titanium dioxide nanomaterials for enhanced visible light photocatalysis显示文摘 | Michael K S Reenamole G Patrick F | | 0，，： | 1 |
| 13 | Multi-symplectic geometry, variational integrators, and nonlinear PDEs 显示文摘 | Marsden J E Patrick G P Shkoller S | 1998 | Communications in Mathematical Physics1998，199，2： | 1 |
| 14 | Molecular identifi- cation of zygomycetes from culture and experimentally infected tissues显示文摘 | Patrick S Strphane B Jean-Charles G | 2006 | J Microbiol2006，44，2： | 1 |
| 15 | Physiologically-based pharmacokinetic simulation modelling 显示文摘 | George M G Patrick J S | 2002 | Advanced Drug Delivery Reviews2002，54，3： | 1 |
| 16 | Analysis of nucleotides and oligonucleotides im-mobilized as self-assembled monolayers by static secondary ion mass spectrometry显示文摘 | PATRICK J S COOKS R G PACHUTA S J | 1994 | Biological Mass Spectrometry1994，23，11： | 1 |
| 17 | Identifying the vulnerable plaque:A review of invasive and non-invasive imaging modalities显示文摘 | Jan G Patrick S Luc M | | 0，，1： | 1 |
| 18 | KIH-485 and S-Metolachlor Efficacy Comparisons in Conventional and No- Tillage Cornl 显示文摘 | PATRICK W G PHILLIP W S JOHN C F | 2006 | Weed Technology2006，20，3： | 1 |
| 19 | A New method for synthesis of trifluoro- methyl-substituted phenols and anilines显示文摘 | Patrick G S Donald R B | 1989 | J Org Chem1989，54，： | 1 |
| 20 | Adaptive wave- let transform for vibration signal modelling and applica- tion in fault diagnosis of water hydraulic motor显示文摘 | CHEN H X Patrick S K Chua Lim G H | 2006 | Me- chanical Systems and Signal Processing2006，20，： | 1 |
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