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135篇 您的检索式:作者名="PARIS B"
    题名 作者 年代 出处 被引量
1二甲双胍与吡格列酮两种2型糖尿病药物在亲水作用色谱上的保留机理研究(英文)显示文摘二甲双胍和吡格列酮是治疗2型糖尿病的常见药物,经常用于同一复方制剂。制药和临床领域常要求同时测定这两种药物。亲水作用色谱近来在医药分析领域展现出良好的前景。本文通过研究流动相的有机溶剂含量、pH值和缓冲盐浓度等参数对色谱保留的影响,从而尝试揭示两种药物在亲水性硅胶柱上的分离机理。流动相中甲醇的增加会导致二甲双胍的保留因子的增加。流动相pH值比较低时,二甲双胍的保留因子会随着pH值升高而增加,而当pH值>6.09,其反而会随着pH值的升高而下降。吡格列酮的保留因子几乎不受甲醇比例和pH值的影响。缓冲盐浓度对两种药物的保留因子几乎都没有影响。因此,对于二甲双胍,亲水作用是主要的保留机理,静电作用和氢键也起到了重要作用。对于吡格列酮,亲水作用是支配性的。经过优化的亲水作用色谱方法可成功地应用到分离测定两种药物在2型糖尿病复方药物中的含量。鲁肖飞 Caroline Martin 戚忠林 Pari Samani Zemen Berhe Dominic B Siaw Shyam K Pahari 左跃钢 2019分析科学学报2019,35,6:4
2Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains显示文摘Paris S Sesboue R Delpech B 2002Int J Cancer2002,97,5:2
3Resistive Interchange Mode in the Presence of Equilibrium Flow显示文摘HOU L PARIS R B WOOD A D 1996Physics of Plasmas American Institute of Physics1996,3,2:1
4Diagnosis and treatment of juvenile nasopharyngeal angiofibroma显示文摘Paris JM Guelfucci B Moulin G 2001Eur Arch Otorhino laryngol2001,258,3:1
5Influence of equilibrium shear flow along the magnetic flows on the resistive tearing instability显示文摘PARIS R B SY W N-C 1983Physics of Fluids1983,26,:1
6Selective protein kinase C isoforms are involved in endothelin-1-induced human uterine contraction at the end of pregnancy显示文摘Eude I Paris B Cabrol D 2000Biol Reprod2000,63,5:1
7Two distinct tumor suppressor loci within chromosome 11P15 implicated In breast cancer progression and maetstasis显示文摘Kamik P Paris M Williajns B 1998Hum Mol Genet1998,7,:1
8A Recurrent Fuzzy-Neural Model for Dynamic System Identification 显示文摘PARIS A MASTOROCOSTAS JOHN B THEOCHARIS 2002IEEE Trans Syst Man Cybern Part B: Cybernetics2002,32,2:1
9Neural networks for multiuser detection in CDMA communication显示文摘 Aazhang B Orsak G 1992IEEE Trans1992,40,1:1
10Exponentially-improved asymptotics for the gamma function显示文摘PARIS R B WOOD A D 1992Comp Appl Math1992,41,:1
11Introduction to Karen Homey显示文摘Paris B J 1996American Journal of Psychoanalysis1996,56,2:1
12Channel Order Estimation via Sample Sorting显示文摘Wood S G Paris B P Nelson J K 2011IEEE Trans on Signal Processing2011,45,2:1
13Karen Homey's vision of the self显示文摘Paris B J 1999American Journal of Psychoanalysis1999,59,2:1
14Diagnosis and treatment of juvenile nasopharyngeal angiofibroma 显示文摘Paris J Guelfucci B Zanaret M 2001Eur Arch Otorhinolaryngol2001,258,:1
15Selective protein kinase C isoforms are involved in endothelin-l-induced human uterine contraction at the end of pregnancy显示文摘Eude I Paris B Cabrol D 2000Biol Reprod2000,63,5:1
16Follow-up of bronchial precancerous lesions and carcinoma in situ using fluorescence endoscopy 显示文摘BOTA S AULIAC J B PARIS C 2001Am J Respir Crit Care Med2001,164,9:1
17Diagnosis and treatment of juvenile nasopharyngeal angiofibroma显示文摘Paris J Guelfucci B Moulin G 2001Eur Arch Otorhinolaryngol2001,258,3:1
18Blood pressure and renal outcomes in patients with kidney infarction and hypertension显示文摘PARIS B BOBRIE G ROSSIGNOL P 2006J Hypertens2006,24,8:1
19A Recurrent Fuzzy-Neural Model for Dynamic System Identifi- cation 显示文摘Paris A Mastorocostas John B Theocharis 2002IEEE Transactions on Systems (S1083-4419)2002,32,2:1
20Intracellular Ca2+ storage in health and disease : a dynamicequilibrium显示文摘Sammels Eva Parys Jan B Missiaen Luding 2010Cell Calcium2010,47,4:1
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