|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021,24,8: | 7 |
| 2 | Evaluation of 5 versus 10 granulocyteaphaeresis sessions in steroid-dependent ulcerative colitis: A pilot, prospective, multicenter, randomized study显示文摘瞄准:与活跃类固醇依赖者 ulcerative 在病人与 10 个 granulocyteaphaeresis 会议相比评估 5 的功效。方法:在这名飞行员,未来,多集中使随机化的试用,有中等活跃的类固醇的 20 个病人 -- 依赖 ulcerative 被使随机化到 5 或 10 个 granulocyteaphaeresis 会议。主要目的是在 wk 的临床的宽恕 17。第二等的措施包括了内视镜的宽恕和类固醇消费。结果:九个病人被使随机化到 5 个 granulocyteaphaeresis 会议(组 1 ) 和 11 个病人到 10 个 granulocyteaphaeresis 会议(组 2 ) 。在 wk 17,在在组 2 的组 1 病人和 45.45% 的 37.5% 病人在临床的宽恕。临床的宽恕被内视镜的宽恕在所有情况中伴随。完成宽恕的百分之 86 个病人在 wk 是没有类固醇的 17。每日的类固醇要求在组 2 是显著地更低的。病人的 89% 在一年后续期间留在宽恕。一个严肃的不利事件不与学习治疗有关,被报导。结论:Granulocyteaphaeresis 为类固醇依赖者 ulcerative 的治疗安全、有效。在这张人口,增加 aphaeresis 会议的数字没与更高的宽恕率被联系,但是负担得起重要类固醇圆材效果。 | Elena Ricart Maria Esteve Montserrat Andreu Francesc Casellas David Monfort Miquel Sans Natalia Oudovenko Raúl Lafuente Julián Panés | 2007 | World Journal of Gastroenterology2007,13,15: | 3 |
| 3 | 饲料中添加蛋白酶对肉鸡性能、养分利用率、肠道形态和胴体品质的影响显示文摘试验在饲喂玉米、高粱为主的肉鸡日粮中补充大豆,并添加蛋白酶,研究蛋白酶对肉鸡性能、养分消化率、肠道形态和胴体品质的影响。试验选取1日龄AA肉仔鸡(43.8±1.31 g)256只,均为公鸡,随机分配到2×2试验设计方阵中,方阵包括正常组(玉米组和高粱组)和蛋白酶组(空白组和添加蛋白酶150 mg·kg^(-1)的试验组)。试验1~21 d为第一阶段,22~42 d为第二阶段。试验结果表明,第二阶段中,日粮中添加蛋白酶极显著提高肉鸡的平均日增重(ADG,P<0.01),在整个试验过程中显著提高(P<0.05)。在各个时期,正常组对肉鸡生产性能均无显著影响(P>0.05)。19~21 d时,添加蛋白酶可显著提高肉鸡的表观代谢能(AME),干物质(DM)、总能量(GE)和养分消化率(P<0.05)。此外,日粮以高粱为主时,AME、GE消化率有降低趋势(P=0.05),氮沉积率也有降低趋势(P=0.08)。40~42 d时,日粮中添加蛋白酶可显著提高AME,DM、GE和氮沉积率(P<0.05)。21 d时,日粮中添加蛋白酶极显著增加肠绒毛高度、肠绒毛与隐窝深度比值,极显著降低十二指肠、空肠、回肠的隐窝深度(P<0.01)。42 d时,日粮中添加蛋白酶显著增加空肠肠绒毛高度、绒毛高度与隐窝深度比值,显著降低隐窝深度(P<0.05)。日粮中添加蛋白酶显著增加胸肌重、24 h p H,显著降低胸肌的滴水损失(P<0.05)。试验结果表明,饲养阶段日粮中添加复合蛋白酶可提高肉鸡ADG;在第一阶段可改善AME、DM、GE和氮沉积率和肠道形态。补充蛋白酶可提高出栏重、胸肌重和24 h pH,降低胸肌的滴水损失。低单宁高粱日粮与玉米日粮相比,对肉鸡性能的影响相近。 | Xu X Wang H L Pan L Ma X K Tian Q Y Xu Y T Long S F Zhang Z H Piao X S | 2017 | 饲料博览2017,0,1: | 2 |
| 4 | Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells 显示文摘 | Chou C C Pan S L Teng C M | 2003 | Eur J Pharm Sci2003,19,5: | 2 |
| 5 | Three-dimensional analysis of single pile response to lateral soil movements显示文摘 | Pan J L Goh A T C Wong K S | 2002 | International Journal for Numerical and Analytical Methods in Geomechanics2002,,26: | 1 |
| 6 | Infertility and testicular defects in hormone-sensitive lipase-deficient mice显示文摘 | Chung S Wang SP Pan L | 2001 | Endocrinology2001,142,10: | 1 |
| 7 | Storage and sequestration potential of topsoil organic carbon in China paddy soil显示文摘 | PAN Gen-Xing Li L Q Wu L S | 2003 | Global Change Biology2003,10,: | 1 |
| 8 | Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes : a genetic substudy of the Plato trial 显示文摘 | Ticagrelor versus clopidogrel in paN Engl J Med 2009 361(11): Wallentin L James S Storey RF | 2010 | Lancet2010,376,9749: | 1 |
| 9 | The Diagnosis of Pneumonia in Renal Transplant Recipients Using Invasive and Noninvasive Procedures显示文摘 | Chang G C Wu C L Pan S H | 2004 | Chest2004,125,3: | 1 |
| 10 | Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK 1 显示文摘 | Zheng L Pan H Li S | 2000 | Mol Cell2000,6,4: | 1 |
| 11 | Prognostic role of micmRNA - 181 a/b in hematological malignancies: a meta - analysis 显示文摘 | Lin S Pan L Guo S | 2013 | PI- oS One2013,8,59: | 1 |
| 12 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009,4,2: | 1 |
| 13 | Nasopharyngeal carcinoma treat- edwith reduced-volume intensity-modulated radiation therapy:report on the 3 year outcome of a prospective series 显示文摘 | LIN S PAN J HAN L | 2009 | Int J Radiat Oncol Biol Phys2009,75,4: | 1 |
| 14 | Room-temperature sta- tionary sodium-ion batteries for large-scale electric energy storage显示文摘 | Pan H L Hu Y S Chen L Q | 2013 | Energy & Environmengtal Science2013,6,8: | 1 |
| 15 | Effect of tauline on human fetal neuron cells: Proliferation and differentiation 显示文摘 | CHEN X C PAN Z L LIU D S | 1998 | Adv Exp Meal Biol1998,442,: | 1 |
| 16 | Urokinase plasmmogen activator/urokmase-specific surface receptor expression and matrix invasion by breast cancer cell requires constitutive p38 alpha mitogen-activated protein kinase activity显示文摘 | Huang S New L Pan Z | 2000 | J Biol Chem2000,27,12: | 1 |
| 17 | Fabrication and characterization of PFSI/ePTFE composite pro- ton exchange membranes of polymer electrolyte fuel cell显示文摘 | TANG H L PAN M JIANG S | 2007 | Eleetrochim Acta2007,52,16: | 1 |
| 18 | A new intelligent electronic nose system for measuring and analysing livestock and poultry farm o- dours显示文摘 | Pan L Yang S X | 2007 | Environ Monit Assess2007,135,13: | 1 |
| 19 | Investigation of Struc- tural ,Optical and Electronic Properties in A1-Sn Co-Doped ZnO Thin Films显示文摘 | Pan Z C Tian X L Wu S K | 2013 | Applied Surface Science2013,265,: | 1 |
| 20 | Quantitative proteomics analysis integrated with microarray data reveals that extracellular matrix proteins,catenins,and p53 binding protein 1 are important for chemotherapy response in ovarian cancers显示文摘 | Pan S Cheng L White JT | 2009 | OMICS2009,13,4: | 1 |