| 1 | An Authenticated Dynamic Key Management Scheme for Clustered Sensor Networks显示文摘Secure sensor networks has received much attention in the last few years.A sensor network always works unattended possibly in a hostile environment such as a battlefield.In such environments,sensor networks are subject to node capture.Constrained energy,memory,and computational capabilities of sensor nodes mandate a clever design of security solutions to minimize overhead while maintaining secure communication over the lifespan of the network.In this paper,an authenticated dynamic key management scheme,ADKM has been proposed.It provides efficient,scalable,and survivable dynamic keying in a clustered sensor network with a large number of sensor nodes.ADKM employs a combinatorial exclusion basis system (EBS) for efficiency and one-way hash chains for authentication.Analysis of security and performance demonstrate that ADKM is efficient in security of sensor networks. | ZHOU Yajian PAN Anwei LI Jiguo | 2010 | China Communications2010，7，4： | 2 |
| 2 | Integration of scRNA and bulk RNA-sequence to construct the 5-gene molecular prognostic model based on the heterogeneity of thyroid carcinoma endothelial cell显示文摘Thyroid cancer(TC)is a kind of cancer with high heterogeneity,which leads to significant difference in prognosis.The prognostic molecular processes are not well understood.Cancer cells and tumor microenvironment(TME)cells jointly determine the heterogeneity.However,quite a little attention was paid to cells in the TME in the past years.In this study,we not only reveal that endothelial cells(ECs)are strongly associated with the progress of papillary thyroid cancer(PTC)using single-cell RNA-seq(scRNA-seq)data downloaded from Gene Expression Omnibus(GEO)and WGCNA,but also screen 5 crucial genes of ECs:CLDN5,ABCG2,NOTCH4,PLAT,and TMEM47.Fur-thermore,the 5-gene molecular prognostic model is constructed,which can predict how well a patient will do on PD-L1 blockade immunotherapy for TC and evaluate prognosis.Quantitative real-time polymerase chain reaction(qRT-PCR)analysis demonstrates that PLAT is decreased in TC and the increase of PLAT can restrain the migratory capacity of TC cells.Meanwhile,in TC cells,PLAT suppresses VEGFa/VEGFR2-mediated human umbilical vascular endothelial cell(HUVEC)proliferation and tube formation.Totally,we construct the 5-gene molecular prognostic model from the perspective of EC and provide a new idea for immunotherapy of TC. | Zhaoxian Ni Shan Cong Hongchang Li Jiazhe Liu Qing Zhang Chuanchao Wei Gaofeng Pan Hui He Weiyan Liu Anwei Mao | 2024 | Acta Biochimica et Biophysica Sinica2024，56，2： | 0 |
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