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| 1 | Oxidative stress modulation in hepatitis C virus infected cells显示文摘Hepatitis C virus(HCV) replication is associated with the endoplasmic reticulum, where the virus can induce cellular stress. Oxidative cell damage plays an important role in HCV physiopathology. Oxidative stress is triggered when the concentration of oxygen species in the extracellular or intracellular environment exceeds antioxidant defenses. Cells are protected and modulate oxidative stress through the interplay of intracellular antioxidant agents, mainly glutathione system(GSH) and thioredoxin; and antioxidant enzyme systems such as superoxide dismutase, catalase, GSH peroxidase, and heme oxygenase-1. Also, the use of natural and synthetic antioxidants(vitamin C and E, N-acetylcysteine, glycyrrhizin, polyenylphosphatidyl choline, mitoquinone, quercetin, S-adenosylmethionine and silymarin) has already shown promising results as co-adjuvants in HCV therapy. Despite all the available information, it is not known how different agents with antiviral activity can interfere with the modulation of the cell redox state induced by HCV and decrease viral replication. This review describes an evidence-based consensus on molecular mechanisms involved in HCV replication and their relationship with cell damage induced by oxidative stress generated by the virus itself and cell antiviral machinery. It also describes some molecules that modify the levels of oxidative stress in HCV-infected cells. | Sonia A Lozano-Sepulveda Owen L Bryan-Marrugo Carlos Cordova-Fletes Maria C Gutierrez-Ruiz Ana M Rivas-Estilla | 2015 | World Journal of Hepatology2015，7，29： | 6 |
| 2 | Calibrating a structured light stripe system: a novel approach 显示文摘 | HUYNH D Q OWENS R A | 1999 | Internation al Journal of Computer Vision1999，33，1： | 2 |
| 3 | Image-guided therapies in the treatment of hepatocellular carcinoma: A multidisciplinary perspective显示文摘A multidisciplinary approach to the treatment of patients with unresectable hepatocellular carcinoma(HCC) has led to improvements in screening, detection,and treatments. Interventional techniques includethermal ablation, transarterial chemoembolization, and radioembolization whilst stereotactic body radiation therapy also uses imaging to target the radiation. Both survival rates and cure rates have improved markedly since the introduction of these techniques. This review article describes the image guided techniques used for the treatment of HCC. | Jonathon Willatt Kevin K Hannawa Julie A Ruma Timothy L Frankel Dawn Owen Pranab M Barman | 2015 | World Journal of Hepatology2015，7，2： | 2 |
| 4 | Short-sale constraints and stock returns显示文摘 | Charles M Jones Owen A Lamont | 2002 | Journal of Financial Economics2002，，2： | 2 |
| 5 | The isothermal austenite-ferrite transformation in some deformed vanadium steels显示文摘 | M J Crooks A J Garratt-Reed J B Vander Sande W S Owen | 1982 | Metallurgical Transactions A1982，，8： | 2 |
| 6 | Lumbar sagittal contour after posterior interbody fusion:threaded devices alone versus vertical cages plus posterior instrumentation显示文摘 | Klemme WR Owens BD Dhawan A | 2001 | Spine2001，26，5： | 1 |
| 7 | An EfficientMultimodal 2D-3D Hybrid Approach to Automatic FaceRecognition显示文摘 | MIAN A S BENNAMOUN M OWENS R | 2007 | IEEE Transactions on Pattern Analysisand Machine Intelligence2007，29，11： | 1 |
| 8 | Empirical likelihood ratio for linear models显示文摘 | Owen A B | 1991 | Ann Statist1991，19，： | 1 |
| 9 | Lumbar sagittal contour after posterior interbody fusion:threa-ded devices alone versus vertical cages plus posterior instrumentation显示文摘 | Klemme WR Owens BD Dhawan A | 2000 | Spine2000，26，： | 1 |
| 10 | Light dependency of VOC emissions from selected mediterranean plant species显示文摘 | S M Owen P Harley A Guenther | 2002 | Atmospheric Environment2002，36，19： | 1 |
| 11 | Protein degradation and fermentation characteristics of red clover and alfalfa silage harvested with varying levels of total nonstructural carbohydrates显示文摘 | Owens V N Albrecht K A Muck R E | 1999 | Crop Science1999，39，： | 1 |
| 12 | A hazardous profession: war, journalists and psychopathology显示文摘 | Feinstein A Owen J Blair N | 2002 | Am J Psychia- try2002，159，9： | 1 |
| 13 | What is central sleep apnea? 显示文摘 | Malhotra A Owens PL | 2010 | Respir Care2010，55，9： | 1 |
| 14 | Controlling correlations in Latin hypercube samples显示文摘 | Owen A B | 1994 | Journal of the American Statistical Association1994，89，428： | 1 |
| 15 | Feature detection from local energy 显示文摘 | Morrone M C Owens R A | 1987 | Pattern Recognition Letters (S0167-8655)1987，6，5： | 1 |
| 16 | Spatial variability analysis of soil physical properties of alluvial soils 显示文摘 | IQBAL J THOMASSON J A JENKINS J N OWENS P R AND WHISLER F D | 2005 | Soil Science Society of America Journal2005，69，： | 1 |
| 17 | Temporal variability of denitrification in estuarine sediments显示文摘 | LAW C S REES A P OWENS N J P | 1991 | Estuarine Coastal and Shelf Science1991，33，1： | 1 |
| 18 | Protein degradation and fermentation characteristics of red clover and alfalfa silage harvested with varying levels of total nonstructural carbohydrates显示文摘 | Owens V N Albrecht K A Muck R E | 1999 | Crop Science1999，39，6： | 1 |
| 19 | Insulin-like Growth Factor 1 Promotes Growth Selectively in fetal sheep in late gestation 显示文摘 | FONG L JULIE A OWENS L | 1996 | AmJPhysiol1996，270，： | 1 |
| 20 | Sex and Age Differences in Victimi-zation and Conflict Resolution among Adolescents in a SouthAustralian School显示文摘 | Owens L Daly A Slee P | 2005 | Aggressive Behavior2005，31，： | 1 |
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