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704篇 您的检索式:作者名="IQBAL J"
    题名 作者 年代 出处 被引量
1尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 2018中华高血压杂志2018,26,12:29
2Increased hepcidin expression in colorectal carcinogenesis显示文摘AIM:To investigate whether the iron stores regulator hepcidin is implicated in colon cancer-associated anae- mia and whether it might have a role in colorectal car- cinogenesis. METHODS: Mass spectrometry (MALDI-TOF MS and SELDI-TOF MS) was employed to measure hepcidin in urine collected from 56 patients with colorectal cancer. Quantitative Real Time RT-PCR was utilised to determine hepcidin mRNA expression in colorectal cancer tissue. Hepcidin cellular localisation was determined using im- munohistochemistry. RESULTS: We demonstrate that whilst urinary hepcidin expression was not correlated with anaemia it was posi- tively associated with increasing T-stage of colorectal cancer (P < 0.05). Furthermore, we report that hepcidin mRNA is expressed in 34% of colorectal cancer tissue specimens and was correlated with ferroportin repres- sion. This was supported by hepcidin immunoreactivity in colorectal cancer tissue. CONCLUSION: We demonstrate that systemic hepcidin expression is unlikely to be the cause of the systemic anaemia associated with colorectal cancer. However, we demonstrate for the first time that hepcidin is expressed by colorectal cancer tissue and that this may represent a novel oncogenic signalling mechanism.Douglas G Ward Keith Roberts Matthew J Brookes Howard Joy Ashley Martin Tariq Ismail Robert Spychal Tariq Iqbal Chris Tselepis 2008World Journal of Gastroenterology2008,14,9:12
3Is iron overload in alcohol-related cirrhosis mediated by hepcidin?显示文摘In this case report we describe the relationship between ferritin levels and hepcidin in a patient with alcohol-related spur cell anemia who underwent liver transplantation.We demonstrate a reciprocal relation-ship between serum or urinary hepcidin and serum ferritin,which indicates that inadequate hepcidin production by the diseased liver is associated with elevated serum ferritin.The ferritin level falls with increasing hepcidin production after transplantation.Neither inflammatory indices(IL6)nor erythropoietin appear to be related to hepcidin expression in this case.We suggest that inappropriately low hepcidin production by the cirrhotic liver may contribute substantially to elevated tissue iron stores in cirrhosis and speculate that hepcidin replacement in these patients may be of therapeutic benefi t in the future.Tariq Iqbal Azzam Diab Douglas G Ward Matthew J Brookes Chris Tselepis Jim Murray Elwyn Elias 2009World Journal of Gastroenterology2009,15,46:2
4BCI2 expression is a prognostic marker for the activated B - cell - like type of diffuse large B - cell lymphoma 显示文摘Iqbal J Neppalli VT Wright G 2006J Clin Oncol2006,24,6:1
5Recent advances in transition metal catalyzed oxidation of organic sub- strates with molecular oxygen显示文摘Punniyamurthy T Velusamy S Iqbal J 2005Chem Rev2005,105,:1
6Effects of central infusion of ghrelin on food intake and plasma levels of growth hormone, luteinizing hormone, prolactin, and cortisol secretion in sheep 显示文摘Iqbal J Kurose Y Canny B 2006Endocrinology2006,147,1:1
7Pancreaticobiliary and duode- nal perforations after periampullary endoscopic proce- dures : diagnosis and management显示文摘Fatima J Baron T H Topazian M D Houghton S G Iqbal C W Ott B J 2007Arch Surg2007,142,:1
8TNF regulates cellulai' NAD + metabolism in prima- ry macrophages 显示文摘Iqbal J Zaidi M 2006Biochem Biophys Res Commun2006,342,4:1
9Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma 显示文摘Iqbal J Shen Y Huang X 2015Blood2015,125,7:1
10Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma 显示文摘Iqbal J Wright G Wang C 2014Blood2014,123,19:1
11Spatial variability analysis of soil physical properties of alluvial soils 显示文摘IQBAL J THOMASSON J A JENKINS J N OWENS P R AND WHISLER F D 2005Soil Science Society of America Journal2005,69,:1
12A high throughput procedure for capturing mierossatellites from complex plant genomes 显示文摘Connell JP Pammi S Iqbal M J 1998Plant Mol Biol Rep1998,16,:1
13Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma显示文摘Iqbal J Wright G Wang C 2014Blood2014,123,19:1
14MicroRNA expression profiling identifies molecular signatures associated with anaplas- tic large cell lymphoma显示文摘Liu C Iqbal J Teruya-Feldstein J 2013Blood2013,122,12:1
15Analysis of genetic variability among Phalaenopsis species and hybrids using amplified fragment length polymorphism显示文摘Chang Y K Veilleux R E Iqbal M J 2009Journal of the American Society for Horticultural Science2009,134,1:1
16Interactions of bovine viral diarrhea virus glycoprotein Eros with cell surface glycosaminoglycans显示文摘IQBAL M FLICK-SMITH H MCCAULEY J W 0,,:1
17Dynamic Modeling and Simulation of a Small Wind-fuel Cell Hybrid Energy System 显示文摘M J Khan M T Iqbal 2005Renewable Energy2005,30,:1
18Raman and photoluminescence properties of highly Cu doped ZnO nanowires fabricated by vapor-liquid-solid process显示文摘ZhuHC Iqbal J Xu H J 2008Journal of Chemical Physies2008,129,:1
19显示文摘Punniyamurthy T Velusamy S Iqbal J 2005Chem Rev2005,105,6:1
20Evaluation of the hypoglycemic effect of Achyranthes aspera in normal and alloxan diabetic rabbits显示文摘Akhtar M S Iqbal J 1991Journal of ethnopharmacology1991,31,:1
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