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| 1 | Vascular calcification:When should we interfere in chronic kidney disease patients and how?显示文摘Chronic kidney disease(CKD) patients are endangered with the highest mortality rate compared to other chronic diseases. Cardiovascular events account for up to 60% of the fatalities. Cardiovascular calcifications affect most of the CKD patients. Most of this calcification is related to disturbed renal phosphate handling. Fibroblast growth factor 23 and klotho deficiency were incriminated in the pathogenesis of vascular calcification through different mechanisms including their effects on endothelium and arterial wall smooth muscle cells. In addition, deficient klotho gene expression, a constant feature of CKD, promotes vascular pathology and shares in progression of the CKD. The role of gut in the etio-pathogenesis of systemic inflammation and vascular calcification is a newly discovered mechanism. This review will cover the medical history, prevalence, pathogenesis, clinical relevance, different tools used to diagnose, the ideal timing to prevent or to withhold the progression of vascular calcification and the different medications and medical procedures that can help to prolong the survival of CKD patients. | Usama Abdel Azim Sharaf El Din Mona Mansour Salem Dina Ossama Abdulazim | 2016 | World Journal of Nephrology2016,5,5: | 10 |
| 2 | Trauma patterns in patients attending the Emergency Department of Jazan General Hospital, Saudi Arabia显示文摘BACKGROUND: Modern civilization and the sharp rise in living standards have led to dramatic changes in trauma pattern in Saudi Arabia. This study aimed to describe the different patterns of injuries of patients attending the Emergency Department of Jazan General Hospital(JGH) in the southwest corner of Saudi Arabia.METHODS: A total number of 1 050 patients were enrolled in the study. A pre-organized data sheet was prepared for each patient attended the Emergency Department of JGH from February 2012 to January 2013. It contains data about socio-demographics, trauma data, clinical evaluation results, investigations as well as treatment strategies.RESULTS: The mean age of the patients was 25.3±16.8 years. Most(45.1%) of the patients were at age of 18–30 years. Males(64.3%) were affected by trauma more common than females. More than half(60.6%) of the patients were from urban areas. The commonest kind of injury was minor injury(60%), followed by blunt trauma(30.9%) and then penetrating trauma(9.1%). The mean time from the incident to arrival at hospital was 41.3±79.8 minutes. The majority(48.2%) of the patients were discharged after management of trivial trauma, whereas 2.3% were admitted to ICU, 7.7% transferred to inpatient wards, and 17.7% observed and subsequently discharged. The mortality rate of the patients was 2.6%.CONCLUSION: Trauma is a major health problem, especially in the young population in Saudi Arabia. Blunt trauma is more frequent than penetrating trauma, with road traffic accidents accounting for the majority. | Emad Hokkam Abdelaziz Gonna Ossama Zakaria Amany El-shemally | 2015 | World Journal of Emergency Medicine2015,6,1: | 7 |
| 3 | Stop chronic kidney disease progression: Time is approaching显示文摘Progression of chronic kidney disease(CKD) is inevitable. However, the last decade has witnessed tremendous achievements in this field. Today we are optimistic; the dream of withholding this progression is about to be realistic. The recent discoveries in the field of CKD management involved most of the individual diseases leading the patients to end-stage renal disease. Most of these advances involved patients suffering diabetic kidney disease, chronic glomerulonephritis, polycystic kidney disease, renal amyloidosis and chronic tubulointerstitial disease. The chronic systemic inflammatory status and increased oxidative stress were also investigated. This inflammatory status influences the antisenescence Klotho gene expression. The role of Klotho in CKD progression together with its therapeutic value are explored. The role of gut as a major source of inflammation, the pathogenesis of intestinal mucosal barrier damage, the role of intestinal alkaline phosphatase and the dietary and therapeutic implications add a novel therapeutic tool to delay CKD progression. | Usama Abdel Azim Sharaf El Din Mona Mansour Salem Dina Ossama Abdulazim | 2016 | World Journal of Nephrology2016,5,3: | 6 |
| 4 | Optimal Seat Suspension Design Using Genetic Algorithms显示文摘 | Wael Abbas Ossama B. Abouelatta Magdy El-Azab Mamdouh El-Saidy Adel A. Megahed | 2011 | Journal of Mechanics Engineering and Automation2011,1,1: | 3 |
| 5 | Multi-modality imaging of cardiac amyloidosis: Contemporary update显示文摘Cardiac amyloidosis is a heterogeneous and challenging diagnostic disease with poor prognosis that is now being altered by introduction of new therapies.Echocardiography remains the first-line imaging tool, and when disease is suspected on echocardiography, cardiac magnetic resonance imaging and nuclear imaging play critical roles in the non-invasive diagnosis and evaluation of cardiac amyloidosis. Advances in multi-modality cardiac imaging allowing earlier diagnosis and initiation of novel therapies have significantly improved the outcomes in these patients. Cardiac imaging also plays important roles in the risk stratification of patients presenting with cardiac amyloidosis. In the current review, we provide a clinical and imaging focused update, and importantly outline the imaging protocols, diagnostic and prognostic utility of multimodality cardiac imaging in the assessment of cardiac amyloidosis. | Tom Kai Ming Wang Ossama K Abou Hassan Wael Jaber Bo Xu | 2020 | World Journal of Radiology2020,12,6: | 2 |
| 6 | In tube condensation heat transfer of CO2 at low temperatures in a horizontal smooth tube显示文摘 | Ossama Iqbal Pradeep Bansal | | 0,,: | 1 |
| 7 | Stem Cell Therapy Improves the Outcome of Liver Resection in Cirrhotics显示文摘 | Alaa Ismail Ossama Fouad Amr Abdelnasser Andaleeb Chowdhury Abdulhafez Selim | 2010 | Journal of Gastrointestinal Cancer2010,,1: | 1 |
| 8 | Lipid vesicles for skin delivery of drugs : Reviewing three decades of re- search 显示文摘 | MUSTAFA M A E OSSAMA Y A V1VIANE F N | 2007 | Int JPharm2007,332,12: | 1 |
| 9 | Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatomacells 显示文摘 | Chayma B Ossama S Emna E G | 2008 | Toxicology2008,254,: | 1 |
| 10 | How the Four Wheels Should Share Forces in an Optimum Cooperative Chass is Con- trol 显示文摘 | OSSAMA M MASATO A | 2006 | Control Engineering Practice2006,,14: | 1 |
| 11 | Hidden genes genetic optimization for variable-size design space problems显示文摘 | Ossama A | 2013 | Journal of Optimization Theory and Applications2013,156,2: | 1 |
| 12 | Comparative study be-tween magnesium sulphate and dexmedetomidine for deliberate hy-potension during middle ear surgery显示文摘 | Ossama H Aboushana B Ahmed M | 2011 | Egyptian Journal of Anaes-thesia2011,27,4: | 1 |
| 13 | Biological treatment of industrial wastes in a photobioreactor显示文摘 | TAMER E AMIN M A OSSAMA E T | 2006 | Water Science Technology2006,53,11: | 1 |
| 14 | Simultaneous optimal distribution of lateral and longitudinal tire forces for the model following control显示文摘 | Ossama Mokhiamar Masato Abe | 2004 | ASME Journal of Dynamic Systems Measurement and Control2004,126,4: | 1 |
| 15 | Endoscopic plantar fascia release, calcaneal drilling and calcaneal spur removal for management of painful heel syndrome显示文摘 | Ossama El Shazly Atef El Beltagy | 2010 | The Foot2010,,4: | 1 |
| 16 | Continuous fluid resuscitation and splenectomy for teatment If uncontrolled hemorrhagic shock afer massive splenic injury 显示文摘 | Ossama Abu Hatoum Yulia BSc Mark Hirsh | 2002 | J Trauma2002,52,: | 1 |
| 17 | The vasculature and inflammatory bowel disease. Contribution to Pathogenesis and Clinical Pathology显示文摘 | Ossama AHatoum David GBinion | 2006 | Inflamm Bowel Dis2006,,: | 1 |
| 18 | HEED, A hybrid, energy-efficient, distributed clustering approach for Ad Hoc sensor networks 显示文摘 | Younis Ossama Fahmy Sonia | 2004 | IEEE Transactions on Mobile Computing2004,3,4: | 1 |
| 19 | N-impulse orbit transfer using genetic algorithms显示文摘 | Ossama Daniele | 2007 | Journal of Spacecraft and Rockets2007,44,2: | 1 |
| 20 | Convolu- tional neural networks for speech recognition 显示文摘 | Ossama A H Mohamedz A R Jiang Hui | 2014 | IEEE Transactions on Audio Speech and Language processing2014,22,10: | 1 |