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| 1 | Signal transducer and activator of transcription 3 regulation by novel binding partners显示文摘Signal transducers and activators of transcription(STATs) mediate essential signals for various biological processes,including immune responses,hematopoiesis,and neurogenesis. STAT3,for example,is involved in the pathogenesis of various human diseases,including cancers,autoimmune and inflammatory disorders. STAT3 activation is therefore tightly regulated at multiple levels to prevent these pathological conditions. A number of proteins have been reported to associate with STAT3 and regulate its activity. These STAT3-interacting proteins function to modulate STAT3-mediated signaling at various steps and mediate the crosstalk of STAT3 with other cellular signaling pathways. This article reviews the roles of novel STAT3 binding partners such as DAXX,zipperinteracting protein kinase,Krüppel-associated box-associated protein 1,Y14,PDZ and LIM domain 2 and signal transducing adaptor protein-2,in the regulation of STAT3-mediated signaling. | Tadashi Matsuda Ryuta Muromoto Yuichi Sekine Sumihito Togi Yuichi Kitai Shigeyuki Kon Kenji Oritani | 2015 | World Journal of Biological Chemistry2015，6，4： | 2 |
| 2 | Early B lymphocyte development: Similarities and differences in human and mouse显示文摘B lymphocytes differentiate from hematopoietic stem cells through a series of distinct stages. Early B cell development proceeds in bone marrow until immature B cells migrate out to secondary lymphoid tissues, such as a spleen and lymph nodes, after completion of immunoglobulin heavy and light chain rearrangement. Although the information about the regulation by numerous factors, including signaling molecules, transcription factors, epigenetic changes and the microenvironment, could provide the clinical application, our knowledge on human B lymphopoiesis is limited. However, with great methodological advances, significant progress for understanding B lymphopoiesis both in human and mouse has been made. In this review, we summarize the experimental models for studies about human adult B lymphopoiesis, and the role of microenvironment and signaling molecules, such as cytokines, transforming growth factor-β superfamily, Wnt family and Notch family, with point-by-point comparison between human and mouse. | Michiko Ichii Kenji Oritani Yuzuru Kanakura | 2014 | World Journal of Stem Cells2014，6，4： | 2 |
| 3 | Adiponeetin, a new melnber of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions ofma erophagesE显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，5： | 1 |
| 4 | Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonoeytic progenitors and the functions of macrophages 显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，5： | 1 |
| 5 | Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the of runctions of macrophage显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，： | 1 |
| 6 | Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the func- tions of macrophages显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，： | 1 |
| 7 | Adponetin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomocytic progenitors and the functions显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，： | 1 |
| 8 | Taxane diterpenoids from Taxus yunnanensis and Taxus cuspidate 显示文摘 | Shi Q W Oritani T Kiyota H | 2000 | Phytochemistry2000，54，8： | 1 |
| 9 | Adiponectin, a new member of the flamily of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macophages显示文摘 | YoktaT Oritani K Takahashi I | 2000 | Blood2000，96，： | 1 |
| 10 | Three new taxane diterpenoids from the seeds of the Japanese yew, Taxus cuspi- date显示文摘 | Shi Q W Oritani T Sugiyama T | 2000 | Nat Prod Lett2000，14，4： | 1 |
| 11 | Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macropha- ges显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，5： | 1 |
| 12 | Two suicide fatalities from sodium cyanide ingestion: differences in blood biochemistry显示文摘 | Zhu B L Oritani S Quan L | 2004 | Chudoku Kenkyu2004，17，： | 1 |
| 13 | Regulation of human B lymphopoiesis by the transforming growth factor-β superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment显示文摘 | Michiko Ichii Kenji Oritani Takafumi Yokota Makoto Nishida Isao Takahashi Takahiro Shirogane Sachiko Ezoe Norimitsu Saitoh Rie Tanigawa Paul W. Kincade Yuzuru Kanakura | 2008 | Experimental Hematology2008，，5： | 1 |
| 14 | Adiponectin,a new member of the family of soluble defense collagens,negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，5： | 1 |
| 15 | Synthesis and antifungal activity of the four stereoisomers of streptimidone,a glutarimide antibiotic from Streptomyces rimosus forma paromomycinus显示文摘 | KONDO H ORITANI T KIYOTA H | 2000 | Eur J Org Chem2000，，20： | 1 |
| 16 | Adiponectin,a new member of the family of soluble defense collagens,negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，： | 1 |
| 17 | Adiponectin,a new member of the family of soluble defense collagens,negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages显示文摘 | Yokota T Oritani K Takahashi I | 2000 | Blood2000，96，5： | 1 |
| 18 | Kinetin-like factors in the root exudates of rice plants显示文摘 | YOSHID R ORITANI T NISHI A | 1971 | Plant & Cell Physiol1971，12，： | 1 |
| 19 | Stromal cell-free condi- tions favorable for human b lymphopoiesis in culture显示文摘 | Ichii M Oritani K Yokota T etal | 2010 | J Immunol Methods2010，359，12： | 1 |
| 20 | Detection of bromisovalum from the bone marrow of skeletonized human remains: a case report with a comparison between gas chromatography/mass spectrometry (GC/MS) and high-performance liquid chromatography/mass spectrometry (LC/ MS) 显示文摘 | Maeda H Oritani S Nagai K | 1997 | ned Sci Law1997，37，3： | 1 |
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