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| 1 | Dendritic Cells as a Pharmacological Target of Traditional Chinese Medicine显示文摘Dendritic cells (DCs) represent a heterogeneous population of professional antigen-presenting cells (APCs) that play a central role in the initiation and regulation of immune responses. There is considerable evidence that DCs can be used as therapeutic targets for pharmacological modulation of immune responses. Traditional Chinese medicine (TCM) has a long-standing history of using herbal medicine in the treatment of variety of human diseases. Many of the clinical effects of TCM have reportedly been attributed to the up- or down-regulation of immune responses. Accumulating evidence indicates that TCM and its components can interfere with immune responses at the earliest stage by targeting key functions of DCs. Here, we review those published studies of TCM with respect to their effects on immunobiological functions of DCs. Investigations based on both chemical entities derived from TCM as well as TCM herbal mixtures are presented. These studies suggest that various TCM herbal medicines have the capacity to inhibit or promote major functions of DCs, such as differentiation, maturation, cytokine production, survival, antigen uptake and presentation as well as trafficking. These studies have revealed novel biological effects of TCM and document the utility of this approach to discover novel biological modifier of DCfunctions derived from natural | Xin Chen Lu Yang O. M. Zack Howard Joost J. Oppenheim | 2006 | Cellular & Molecular Immunology2006，3，6： | 9 |
| 2 | Vanishing bile duct syndrome in human immunodeficiency virus infected adults:A report of two cases显示文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes. | Ana Paula Oppenheimer Christopher Koh Mary McLaughlin John C Williamson Thomas D Norton Jennifer Laudadio Theo Heller David E Kleiner Kevin P High Caryn G Morse | 2013 | World Journal of Gastroenterology2013，19，1： | 8 |
| 3 | Comparison of Maternal Risk Factors between Placental Abruption and Placenta Previa显示文摘 | Qiuying Yang Shi Wen Karen Phillips Lawrence Oppenheimer Douglas Black Mark Walker | 2009 | Amer J Perinatol2009，，04： | 3 |
| 4 | Circuit implementation of synchronization chaos with applications to communications 显示文摘 | Cuomo K M Oppenheim A V | 1993 | Int Bifurcation Chaos1993，，3： | 2 |
| 5 | Signal reconstruction from phase or magnitude显示文摘 | Hayes H M Lim J S Oppenheim A V | 1980 | IEEE Trans on Acoustics Speech and Signal Processing1980，28，6： | 2 |
| 6 | 急性卒中的并发症显示文摘急性卒中之所以值得注意并非因其所致的损害,而是其可恢复程度。然而,恢复与生存均需视大脑、全身性及心脏的合并症所致损伤而定。病因因中风后时间不同而异。本文综述急性卒中各种并发症。脑部并发症卒中诱发的总死亡率约为20%;幕上梗塞的死亡率为15%,幕下(脑干)为58%。幕下出血的致死率为31%。经幕疝和脑水肿在发病头一周,经幕疝是最常见的死亡原因。在脑出血24小时内和脑梗塞4~5天内,经幕疝的发生率达高峰期。 | OppenheimerS HachinskiV 胡发明 | 1993 | 国外医学(内科学分册)1993，20，4： | 2 |
| 7 | Helium versus oxygen for tracheal gas insufflation during mechanical ventilation 显示文摘 | Pizov R Oppenheim A Eidelman L | 1998 | Crit Care Med1998，26，2： | 2 |
| 8 | Circuit implementation of synchronized chaos with application to communications显示文摘 | CUOMO K M OPPENHEIM A V | 1993 | Phys Rev Lett1993，71，1： | 2 |
| 9 | Real time design and animation of fractal plants and trees显示文摘 | Peter E. Oppenheimer | 1986 | ACM SIGGRAPH Computer Graphics1986，，4： | 2 |
| 10 | The effect of thermal exposure on the mechanical properties of 2099-T6 die forgings, 2099-T83 extrusions, 7075-T7651 plate, 7085-T7452 die forgings, 7085-T7651 plate, and 2397-T87 plate aluminum alloys显示文摘 | J. Jabra M. Romios J. Lai E. Lee M. Setiawan J. R. Ogren R. Clark T. Oppenheim O. S. Es-Said E. W. Lee N. Abourialy W. E. Frazier J. Witters | 2006 | Journal of Materials Engineering and Performance2006，，5： | 2 |
| 11 | Experience with postmortem computed tomography in the forensic analysis of the November 2015 Paris attacks显示文摘Several reports discuss the added value of postmortem computed tomography(PMCT)in the forensic analysis of mass fatality incidents(MFIs),such as the 2009 Victorian bushfires,the Grenfell tower disaster and the MH17 plane crash[1–5].In France,the first deployment of PMCT in an MFI took place during the forensic analysis of the November 2015 Paris terrorist attacks. | Laura W.de Jong Laurence Legrand Tania Delabarde Ghazi Hmeydia Myriam Edjlali Lilia Hamza Joseph Benzakoun Catherine Oppenheim Bertrand Ludes Jean-Francois Meder | 2020 | Forensic Sciences Research2020，5，3： | 2 |
| 12 | ln vivo recombineering of bacteriophage lambda by PCR fragments and single-strand oligonucleotides显示文摘 | Oppenheim AB Rattray AJ Bubunenko M | 2004 | Virology2004，319，2： | 1 |
| 13 | Cell death during development of the nervous system显示文摘 | Oppenheim R W | 1991 | Ann Rev Neurosci1991，14，： | 1 |
| 14 | Distribution and characterization of staphylococcal interspersed repeat units(SIRUs)and potential use for strain differentiation显示文摘 | Hardy KJ Ussery DW Oppenheim BA | 2004 | Microbiology2004，150，12： | 1 |
| 15 | Electrophysiological evidence for reciprocal insulo-insular connectivity of baroreceptor-related neurons 显示文摘 | Zhang Z Oppenheimer SM | 2000 | Brain Res2000，863，： | 1 |
| 16 | Brain-derived neurotrophic fac tor rescues developing avian motoneurons from cell death显示文摘 | Oppenheim RW Yin QW Yan Q | 1992 | Nature1992，360，6406： | 1 |
| 17 | Diffusion-weighted imageing patterns of brain damage associated with cerebral venous thrombosis显示文摘 | Ducreux D Oppenheim C Vandamme X | 2001 | AJNR AM J Neuroradiol2001，22，2： | 1 |
| 18 | Complications of acute stroke显示文摘 | OPPENHEIMER S HACHINSKI V | 1992 | Lancet1992，339，21： | 1 |
| 19 | Skin testing: a survey of allergists 显示文摘 | Oppenheimer J Nelson HS | 2006 | Ann Allergy Asthma Immunol2006，96，1： | 1 |
| 20 | The cardiac consequences ofstroke显示文摘 | Oppenheimer SM Hachinski VC | 1992 | Neurol Clin1992，10，1： | 1 |
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