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| 1 | Relationship between post-ERCP pancreatitis and the change of serum amylase level after the procedure显示文摘AIM: To clarify the relationship between the change of serum amylase level and post-ERCP pancreatitis. METHODS: Between January 1999 and December 2002, 1291 ERCP-related procedures were performed. Serum amylase concentrations were measured before the procedure and 3, 6, and 24 h afterward. The frequency and severity of post-ERCP pancreatitis and the relationship between these phenomena and the change in amylase level were estimated. RESULTS: Post-ERCP pancreatitis occurred in 47 patients (3.6%). Pancreatitis occurred in 1% of patients with normal amylase levels 3 h after ERCP, and in 1%, 5%, 20%, 31% and 39% of patients with amylase levels elevated 1-2 times, 2-3 times, 3-5 times, 5-10 times and over 10 times the upper normal limit at 3 h after ERCP, respectively (level < 2 times vs ≥ 2 times, P < 0.001). Of the 143 patients with levels higher than the normal limit at 3 h after ERCP followed by elevation at 6 h, pancreatitis occurred in 26%. In contrast, pancreatitis occurred in 9% of 45 patients with a level higher than two times the normal limit at 3 h after ERCP followed by a decrease at 6 h (26% vs 9%, P < 0.05). CONCLUSION: Post-ERCP pancreatitis is frequently associated with an increase in serum amylase level greater than twice the normal limit at 3 h after ERCP with an elevation at 6 h. A decrease in amylase level at 6 h after ERCP suggests the unlikelihood of development of post-ERCP pancreatitis. | Kei Ito Naotaka Fujita Yutaka Noda Go Kobayashi Jun Horaguchi Osamu Takasawa Takashi Obana | 2007 | World Journal of Gastroenterology2007，13，28： | 19 |
| 2 | Pancreatic guidewire placement for achieving selective biliary cannulation during endoscopic retrograde cholangio-pancreatography显示文摘AIM: To investigate the frequency and risk factors for acute pancreatitis after pancreatic guidewire placement (P-GW) in achieving cannulation of the bile duct during endoscopic retrograde cholangio-pancreatography (ERCP). METHODS: P-GW was performed in 113 patients in whom cannulation of the bile duct was difficult. The success rate of biliary cannulation, the frequency and risk factors of post-ERCP pancreatitis, and the frequency of spontaneous migration of the pancreatic duct stent were investigated. RESULTS: Selective biliary cannulation with P-GW was achieved in 73% of the patients. Post-ERCP pancreatitis occurred in 12% (14 patients: mild, 13; moderate, 1). Prophylactic pancreatic stenting was attempted in 59% of the patients. Of the 64 patients who successfully underwent stent placement, three developed mild pancreatitis (4.7%). Of the 49 patients without stent placement, 11 developed pancreatitis (22%: mild, 10; moderate, 1). Of the five patients in whom stent placement was unsuccessful, two developed mild pancreatitis. Univariate and multivariate analyses revealed no pancreatic stenting to be the only significant risk factor for pancreatitis. Spontaneous migration of the stent was observed within two weeks in 92% of the patients who had undergone pancreatic duct stenting.CONCLUSION: P-GW is useful for achieving selective biliary cannulation. Pancreatic duct stenting after P-GW can reduce the incidence of post-ERCP pancreatitis, which requires evaluation by means of prospective randomized controlled trials. | Kei Ito Naotaka Fujita Yutaka Noda Go Kobayashi Takashi Obana Jun Horaguchi Osamu Takasawa Shinsuke Koshita Yoshihide Kanno | 2008 | World Journal of Gastroenterology2008，14，36： | 14 |
| 3 | A prospective, randomized, double-blind, controlled trial on the efficacy of carbon dioxide insufflation in gastric endoscopic submucosal dissection显示文摘 | Y. Maeda D. Hirasawa N. Fujita T. Obana T. Sugawara T. Ohira Y. Harada T. Yamagata K. Suzuki Y. Koike J. Kusaka M. Tanaka Y. Noda | 2013 | Endoscopy2013，，05： | 4 |
| 4 | Histological changes at an endosonography-guided biliary drainage site:A case report显示文摘Endosonography-guided biliary drainage (ESBD) is a new method enabling internal drainage of an obstructed bile duct. However,the histological conditions associated with fistula development via the duodenum to the bile duct have not been reported. We performed ESBD 14 d preoperatively in a patient with an ampullary carcinoma and histologically confirmed changes in and around the fistula. The female patient developed no complications relevant to ESBD. Levels of serum bilirubin and hepatobiliary enzymes declined quickly,and pancreatoduodenectomy was carried out uneventfully. The resected specimen was sliced and stained with hematoxylin-eosin. Histological evaluation of the puncture site in the duodenum and bile-duct wall,and the sinus tract revealed no hematoma,bile leakage,or abscess in or around the sinus tract. Little sign of granulation,fibrosis,and inflammatory cell infiltration was observed. Although further large-scale confirmatory studies are needed,the findings here may encourage more active use of ESBD as a substitute for percutaneous transhepatic drainage in cases with failed/difficult endoscopic biliary stenting. | Naotaka Fujita Yutaka Noda Go Kobayashi Kei Ito Takashi Obana Jun Horaguchi Osamu Takasawa Kazunari Nakahara | 2007 | World Journal of Gastroenterology2007，13，41： | 4 |
| 5 | Can pancreatic duct stenting prevent post-ERCP pancreatitis in patients who undergo pancreatic duct guidewire placement for achieving selective biliary cannulation? A prospective randomized controlled trial显示文摘 | Kei Ito Naotaka Fujita Yutaka Noda Go Kobayashi Takashi Obana Jun Horaguchi Osamu Takasawa Shinsuke Koshita Yoshihide Kanno Takahisa Ogawa | 2010 | Journal of Gastroenterology2010，，11： | 2 |
| 6 | A pilot study to assess mediastinal emphysema after esophageal endoscopic submucosal dissection with carbon dioxide insufflation显示文摘 | Y. Maeda D. Hirasawa N. Fujita T. Obana T. Sugawara T. Ohira Y. Harada T. Yamagata K. Suzuki Y. Koike Y. Yamamoto Z. Kusaka Y. Noda | 2012 | Endoscopy2012，，06： | 2 |
| 7 | Comparative study of the phototoxicity of two chlorin type photosensitizers,ATX-S10 (Na) and verteporfin, on vascular endothelial and retinal pig- ment epithelial cells 显示文摘 | Huang Y Obana A Gohto Y Nakajima S | 2004 | Lasers Surg Med2004，34，3： | 1 |
| 8 | Determination of Acetamiprid, Imidacloprid, and Nitenpyram Residues in Vegetables and Fruits by High-performance Liquid Chromatography with Diode-army Detection显示文摘 | OBANA H OKIHASHI M AKUTSU K | 2002 | Agric Food Chem2002，50，16： | 1 |
| 9 | Indocyanine green angiographic as- pects of multiple evanescent white dot syndrome 显示文摘 | Obana A Kusumi M Miki T | 1996 | Retina1996，16，2： | 1 |
| 10 | Determination of pesticide residues in onion,using a microwave oven显示文摘 | Okihashi M Obana H Hori S | | 0，，01： | 1 |
| 11 | Case report:suppurative arthritis due to group B Streptococcus in a patient with rheumatoid arthritis显示文摘 | Obana M Hanada T Ohta S | 1993 | Kansenshogaku Zasshi1993，67，4： | 1 |
| 12 | Survey of complications of in- docyanine green angiography in Japan 显示文摘 | Obana A Miki T Hayashi K | 1994 | Am J Ophthalmol1994，118，6： | 1 |
| 13 | Analysis of NPHS1, NPHS2, ACTN4, and WT1 in Japanese patients with congenital nephrotic syndrome显示文摘 | Sako M Nakanishi K Obana M | 2005 | Kidney Int2005，67，4： | 1 |
| 14 | Determination of organophosphorus pesticidesin foods using ASE system显示文摘 | Obana H Kikuchi K Okihashi M | 1997 | The Analyst1997，122，3： | 1 |
| 15 | Determination of pesticide residues in onion, using a microwave oven 显示文摘 | Okihashi M Obana H Hori S | 1996 | Food Hygienic Society1996，37，1： | 1 |
| 16 | GC/MS analysis of polybrominated diphenyl ethers in fish collected from the Inland Sea of Seto,Japan显示文摘 | Hirotaka Obana Masahiro Okihashi | 2001 | Chemosphere2001，44，： | 1 |
| 17 | Enhanced turnover of transitory starch by expression of up-regulated ADP-glucose pyrophosphorylases in Arabidopsis thaliana显示文摘 | Obana Y Omoto D Kato C | | 0，，： | 1 |
| 18 | GC/MS analysis of polybrominated diphenylethersin fish collected from the inland sea of Seto, Japan 显示文摘 | Akutsu K Obana H Okihash I M | 2001 | Chemosphere2001，44，： | 1 |
| 19 | GC/MS anylysis of ploybrominated diphenyl ethers in fish collected from the in- land sea of seta, Japan 显示文摘 | AKUTSU K OBANA H OKIHASHI M | 2001 | Chemosphere2001，44，： | 1 |
| 20 | Determination of aceamiprid, imidacloprid and nitenpyram residues in vegetables and fruits by high-performance liquid chromatography with diode-array detection显示文摘 | Obana H Okihashi M Akutsu K | 2002 | J Agric Food Chem2002，50，16： | 1 |
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