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| 1 | Dermatofibrosarcoma protuberans: from translocation to targeted therapy显示文摘Dermatofibrosarcoma protuberans(DFSP), the most common dermal sarcoma, is a low-grade, slow growing fibroblastic malignant neoplasm that most frequently affects middle aged adults and is characterized by a high local recurrence rate and a low propensity for metastasis. Wide surgical resection or Mohs micrographic surgery(MMS) are the preferred approaches for localized disease, while radiation therapy is warranted for inoperable disease or for cases with positive margins where re-excision is not possible. DFSP is generally regarded as refractory to conventional chemotherapy. Treatment options for systemic disease were limited until the discovery of a unique translocation, t(17;22)(q22;q13)(COL1A1;PDGFB) found in a majority of cases. In recent years, imatinib, a PDGFβR, ABL and KIT inhibitor, has revolutionized systemic therapy in DFSP. In this review, we summarize the epidemiological, clinical, histological and genetic characteristics of DFSP and update the readers on its current management. | Jonathan Noujaim Khin Thway Cyril Fisher Robin L.Jones | 2015 | Cancer Biology & Medicine2015，12，4： | 4 |
| 2 | Techniques for and outcome of liver transplantation in neonates and infants weighing up to 5 kilograms显示文摘 | Noujaim HM Mayer DA Buckles JAC | 2002 | J Pediatr Surg2002，37，1： | 1 |
| 3 | CT and MRI imaging of neurocysticercosis 显示文摘 | Noujaim SE Rossi MD Rao SK | 1999 | A JR Am J Roentgenol1999，173，6： | 1 |
| 4 | Paraganglioma of the temporal bone:role of magnetic resonance imaging versus computed tomography显示文摘 | Noujaim SE Pattekar MA Cacciarelli A etal | 2000 | Top Magn Reson Imaging2000，11，2： | 1 |
| 5 | Calcineurin and the biologic effect of cyclosporine and tacrolimus显示文摘 | Halloran PF Kung L Noujaim J | 1998 | Transplant Proc1998，30，21： | 1 |
| 6 | Paraganglioma of the temporal bone: role of magnetic resonance imaging versus computed tomography 显示文摘 | Noujaim SE Pattekar MA Cacciarelli A | 2000 | Top Magn Reson Imaging2000，11，2： | 1 |
| 7 | Epithelioid Sarcoma: Opportu- nities for Biology-Driven Targeted Therapy显示文摘 | Noujaim J Thway K Bajwa Z | 2015 | Front Oncol2015，5186，： | 1 |
| 8 | Calcineurin and the biological effect of cyclosporine and tacrolimus显示文摘 | Halloran P F Kung L Noujaim J | 1998 | Transplant Proc1998，30，5： | 1 |
| 9 | N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells显示文摘 | Noujaim D van Golen CM van Golen KL Grauman A Feldman EL | 2002 | Oncogene2002，21，29： | 1 |
| 10 | Techniques for and outcome of liver transplantation in neonates and infants weighing up to 5 kilograms显示文摘 | Noujaim HM Mayer DA Buckles JAC | 2002 | J pediatr Surg2002，37，1： | 1 |
| 11 | Paraganglioma of the temporal bone:Role of magnetic resonance imaging versus computed tomography显示文摘 | Pattekar MA Cacciarelli A | 2000 | Top Magn Reson Imaging2000，11，2： | 1 |
| 12 | Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachyeardia 显示文摘 | Cerrone M Noujaim SF Tolkacheva EG | 2007 | Circ Res2007，101，： | 1 |
| 13 | Paraganglioma of the temporal bone: role of magnetic resonance imaging versus computed tomography显示文摘 | Noujaim E Pattekar A Cacciarelli A | 2000 | Magnetic Resonance Imaging2000，11，： | 1 |
| 14 | Paraganglioma of the temporal bone:Role of magnetic resonance imaging versus computed tomography显示文摘 | Noujaim SE Pattekar MA Cacciarelli A | | 0，，02： | 1 |
| 15 | Struc- tural bases for the different anti-fibrillatory effects of chloro- quine and quinidine显示文摘 | Noujaim SF Stuckey JA Ponce-Balbuena D | 2011 | Cardiovasc Res2011，89，4： | 1 |
| 16 | Universal scal- ing law of electrical turbulence in the mammalian heart 显示文摘 | Noujaim SF Berenfeld O Kalifa J | 2007 | Proc Natl Acad Sci USA2007，104，20： | 1 |
| 17 | Up-regulation of the inward reetifier K eurrent(Ik1) in the mouse heart aeeelerates and stabilizers rotors显示文摘 | Noujaim SF Pandit SV Berenfeld O | 2007 | Journal of Physiology2007，578，： | 1 |
| 18 | Single-Balloon Enteroscopy for Treating Roux-en-y Choledochojejunostomy Stenosis After Liver Transplantation: A Case Report显示文摘 | A. Costa-Genzini W. Takahashi R.G. dos Santos M.T.C.O. Gaboardi H.M. Noujaim E.T. Yamashita M. Perosa T. Genzini | 2012 | Transplantation Proceedings2012，，8： | 1 |
| 19 | Does country of brand origin (COBO) matter for the Lebanese consumers?显示文摘 | Zafar U. Ahmed Imad J. Zbib Arif Sikander Ralph Gilbert Noujaim | 2012 | EuroMed Journal of Business2012，，2： | 1 |
| 20 | Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia显示文摘 | Cerrone M Noujaim SF Tolkacheva EG Talkachou A O'Connell R Berenfeld O | 2007 | Circ Res2007，101，10： | 1 |
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