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| 1 | Outcomes of locally advanced prostate cancer:a single institution study of 209 patients in Japan显示文摘瞄准:为了与局部地先进 / 临床的阶段 III 为亚洲人口调查结果,前列腺癌症(PCa ) 与当前占优势的形式对待。方法:我们考察了在在 1992 和 2003 之间的 Niigata 癌症中心医院被对待的有临床的阶段 III PCa 的 209 个病人的记录。治疗选择包括了荷尔蒙联合治疗的激进的前列腺切除术(RP+HT ) ,荷尔蒙联合治疗的外部横梁照耀(EBRT+HT ) 和主要荷尔蒙治疗(PHT ) 。结果:5 年、 10 年的全面幸存率分别地在所有队是 80.3% 和 46.1% 。幸存率在 RP+HT 组,是 87.3% 和 66.5%94.9% 和 70.0% 在 EBRT+HT 组织, 66.1% 和 17.2% 分别地在 PHT 组织。重要幸存优点在 PHT 与那相比在 EBRT+HT 组被发现的 A 组织(P <
0.0001 ) 。另外, RP+HT 组织幸存最好比 PHT 组织(P = 0.0107 ) 。为所有情况的 5 年、 10 年的疾病特定的幸存率分别地是 92.5% 和 80.0% 。他们在 RP+HT 组,是 93.8% 和 71.4%96.6% 和 93.6% 在 EBRT+HT 组织, 88.6% 和 62.3% 分别地在 PHT 组织。一个幸存优点与 PHT 组相比在 EBRT+HT 组被发现(P = 0.029 ) 。没有有效差量在在 EBRT+HT 和 RP+HT 组之间或在 RP+HT 和 PHT 组之间的疾病特定的幸存被发现。结论:尽管我们的调查结果显示那放射疗法,正 HT 在 PCa 的这个阶段有一个幸存优点,我们推荐与临床的阶段 III PCa 为亚洲人考虑 patients'social 和医药条件的治疗。 | ToshihiroSaito YasuoKitamura ShuichiKomatsubara YasuoMatsumoto TadashiSugita Noboru Hara | 2006 | Asian Journal of Andrology2006,8,5: | 8 |
| 2 | Retroperitoneal disorders associated with Ig G4-related autoimmune pancreatitis显示文摘Ig G4-related autoimmune pancreatitis is frequently accompanied by relevant lesions in the genitourinary tract and retroperitoneal organs, which cause various clinical problems, ranging from non-specific back pain or bladder outlet obstruction to renal failure. The diagnosis of Ig G4-related retroperitoneal fibrosis requires a multidisciplinary approach, including serological tests, histological examination, imaging analysis, and susceptibility to steroid therapy. Radiological examinations are helpful to diagnose this condition, but surgical resection is occasionally unavoidable to exclude malignancy, particularly for patients with isolated retroperitoneal involvement. Steroid therapy is the treatment of choice for this condition, the same as for other manifestationsof Ig G4-related disease.For patients with severe ureteral obstruction,additional ureteral stenting needs to be considered prior to steroid therapy to preserve the renal function.Some papers have suggested that Ig G4-related disease can affect male reproductive organs including the prostate and testis.Ig G4-related prostatitis usually causes lower urinary tract symptoms,such as dysuria and pollakisuria.Patients sometimes state that corticosteroids given for Ig G4-related disease at other sites relieve their lower urinary tract symptoms,which leads us to suspect prostatic involvement in this condition.Because of the limited number of publications available,further studies are warranted to better characterize Ig G4-related disease in male reproductive organs. | Noboru Hara Makoto Kawaguchi Keisuke Takeda Yoh Zen | 2014 | World Journal of Gastroenterology2014,20,44: | 4 |
| 3 | Oncological results, functional outcomes and health-related quality-of-life in men who received a radical prostatectomy or external beam radiation therapy for localized prostate cancer: a study on long-term patient outcome with risk stratification显示文摘在激进的前列腺切除术(RP ) 或外部横梁放射治疗(EBRT ) 以后的健康相关的 quality-of-life (HRQOL ) 没在与疾病风险层化的关系与 oncological 结果一起被学习。而且,这些治疗途径的长期的结果没被学习。我们回顾地分析了在收到 RP 的连续病人之间的 oncological 结果(n = 86 ) 并且 EBRT (n = 76 ) 为局部性的前列腺癌症。HRQOL 和功能的结果能在 62 RP (79%) 和 54 EBRT (79%) 被估计在一个 3 年的后续时期上的病人(中部:41 个月) 用医药结果学习,短 Form-36 (SF-36 ) 和加利福尼亚大学洛杉机前列腺癌症索引(UCLA 一种总线标准) 。5 年的生物化学的没有前进的幸存没在 RP 和 EBRT 组之间不同为低风险(74.6% 对 75.0% , P = 0.931 ) 并且中间风险(61.3% 对 71.1% , P = 0.691 ) 病人。为高风险的病人,没有前进的幸存比在 EBRT 组(79.7%) 在 RP 组(45.1%) 是更低的(P = 0.002 ) 。一般 HRQOL 在二个组之间是可比较的。关于功能的结果, RP 组比 EBRT 组在尿功能和不太尿的麻烦和性麻烦上报导了更低的分数(P < 0.001, P < 0.05 并且 P < 0.001,分别地) 。与风险层化,在 RP 组的低风险、中间风险的病人在 EBRT 组比病人报导了更差的尿功能(P < 0.001 为各个) 。在 EBRT 组的高风险的病人的性功能比一样的风险 RP 病人的好(P < 0.001 ) 。生物化学的复发没在任何一个组与 UCLA 一种总线标准分数被联系。在结论,低 -- 可以在长期的后续期间向与 RP 对待的中间风险的病人汇报相对减少的尿功能。病人在治疗以后的 HRQOL 没取决于生物化学的复发。 | Itsuhiro Takizawa Noboru Hara Tsutomu Nishiyama Masaaki Kaneko Tatsuhiko Hoshii Emiko Tsuchida Kota Takahashi | 2009 | Asian Journal of Andrology2009,11,3: | 3 |
| 4 | 总体和自由型前列腺特异抗原指数在日本人群前列腺癌筛选中的价值和局限性(英文)显示文摘目的:在日本某单机构中评定前列腺特异抗原指数(f/tPSA)的价值和局限性,重点在于避免无意义的前列腺组织活检。方法:631名年龄在44-93岁之间(平均年龄69.8岁)的男性,在日本新滹中心医院用能量多普勒超声波图像引导的经直肠10-点前列腺组织活检后发现其 PSA 值增加,用总体前列腺特异抗原 (tPSA)和前列腺特异抗原指数(f/tPSA)观察组织学特征。结果:在134名 tPSA 为26 ng/mL 或更高病人中,126人(94.3%)检测到前列腺癌(PCa),tPSA 为21-25 ng/mL 时的 PCa 检出率是59.4%,16-20 ng/mL 时为39.2%,11-15 ng/mL 时为30.0%,4.1-10 ng/mL 时为20.0%,小于等于4.0 ng/mL 时为7.6%。在任何一个 tPSA 值区间,PCa 组的 f/tPSA 值都明显低于非肿瘤组(平均为0.122vs.0.160,P<0.001)。接收器特性法表明,对于 tPSA 值在3.0-10 ng/mL(P<0.01)之间的病人,f/tPSA(AUC:0.664)比 tPSA(AUC:0.559)更有价值。虽然以 f/tPSA 等于0.250为分界点可能产生1.8%的 PCa 漏诊率,但是这样有可能节约9.2%不必要的组织活检。结论:对预测 PCa 发病率,f/tPSA 比单独的 tPSA 更有价值。因此,对于被称为 tPSA 灰色地带的亚洲男性来说,我们推荐在 PCa 筛查中用0.250作为 f/tPSA分界点。 | Noboru Hara YasuoKitamura ToshihiroSaito ShuichiKomatsubara | 2006 | Asian Journal of Andrology2006,8,4: | 2 |
| 5 | Uptake Rates of lSF-Fluorodeoxyglucose and C-Choline in tung cancer and pulmonary tuberculosis显示文摘 | Toshihiko Hara Noboru Kosaka Tsuneo Suzuki | 2003 | Chest2003,124,3: | 1 |
| 6 | A case of inflammatory malignant fibrous histiocytoma of the colon显示文摘 | Ikuo Murata M.D. Kazuya Makiyama Kenichi Miyazaki Arthur Sdahiro Kawamoto Noboru Yoshida Koki Muta Minoru Itsuno Kohei Hara Toru Nakagoe Masao Tomita Nobuo Tsuda | 1993 | Gastroenterologia Japonica1993,,4: | 1 |
| 7 | Chordoid meningioma显示文摘 | Hirohito Yano Jun Shinoda Akiara Hara Kuniyasu Shimokawa Noboru Sakai | 2000 | Brain Tumor Pathology2000,,3: | 1 |
| 8 | Formation and breakdown of surface films on magnesium and its alloys in aqueous solutions显示文摘 | Nobuyoshi Hara Yasuhiro Kobayashi Daisuke Kagaya Noboru Akao | 2006 | Corrosion Science2006,,1: | 1 |
| 9 | PET Imaging of Brain Tumor With choline显示文摘 | Toshihiko Hara Noboru kosaka | 1997 | J Nucl Med1997,38,6: | 1 |
| 10 | PET Imaging of Prostate Cancer Using Carbon-11-Choline显示文摘 | Toshihiko Hara Noboru kosaka | 1998 | J Nucl Med1998,39,6: | 1 |
| 11 | Uptake rates of ^18F-fluorodeoxyglucose and HC-Choline in lung cancer and pulmonary tuberculosis 显示文摘 | Toshihiko Hara Noboru Kosaka Tsuneo Suzuki | 2003 | Chest2003,124,3: | 1 |
| 12 | PET Imaging of Brain Tumor With choline显示文摘 | Toshihiko Hara Noboru kosaka | 1997 | J Nucl Med1997,38,6: | 1 |
| 13 | PET Imaging of Prostate Cancer Using Carbon-11-Choline显示文摘 | Toshihiko Hara Noboru kosaka | 1998 | J Nucl Med1998,39,6: | 1 |
| 14 | PET imaging of brain tumor with choline显示文摘 | Toshihiko Hara Noboru Kosaka Nobusada Shi- noura | 1997 | The Journal of Nuclear Medicine1997,38,: | 1 |
| 15 | PET imaging of prostate cancer using carbon-11- choline 显示文摘 | Toshihiko Hara Noboru Kosaka Hiroichi Kishi | 1998 | The Journal of Nuclear Medicine1998,39,: | 1 |
| 16 | Primary solitary fibrous tumor (SFT) in the retroperitoneum显示文摘 | Itsuhiro Takizawa Toshihiro Saito Yasuo Kitamura Kei Arai Makoto Kawaguchi Kota Takahashi Noboru Hara | 2008 | Urologic Oncology: Seminars and Original Investigations2008,,3: | 1 |