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| 1 | Effect of preoperative biliary drainage on outcome of classical pancreaticoduodenectomy显示文摘AIM: To investigate the role of preoperative biliary drainage (PBD) in the outcome of classical pancreaticodu odenectomy. METHODS: A 10-year retrospective data analysis was performed on patients (n = 48) undergoing pancreaticoduodenectomy from March 1994 to March 2004 in department of surgery at SMS medical college, Jaipur, India. Demographic variables, details of preoperative stenting, operative procedure and post operative complications were noted. RESULTS: Preoperative biliary drainage was performed in 21 patients (43.5%). The incidence of septic complications was significantly higher in patients with biliary stent placement (P < 0.05, 0 vs 4). This group of patients also had a significantly higher minor biliary leak rate. Mortality and hospital stay in each group was comparable. CONCLUSION: Within this study population the use of PBD by endoscopic stenting was associated with a high incidence of infective complications. These findings do not support the routine use of biliary stenting in patients prior to pancreatico-duodenectomy. | Chandra Shekhar Bhati Chandrashekhar Kubal Pankaj Kumar Sihag Ankur Atal Gupta Raj Kamal Jenav Nicholas G Inston Jagdish M Mehta | 2007 | World Journal of Gastroenterology2007，13，8： | 12 |
| 2 | Prevalence of the Activating JAK2 Tyrosine Kinase Mutation V617F in the Budd–Chiari Syndrome显示文摘 | Raj K. Patel Nicholas C. Lea Michael A. Heneghan Nigel B. Westwood Dragana Milojkovic Murugaiyan Thanigaikumar Deborah Yallop Roopen Arya Antonio Pagliuca Joop G?ken Julia Wendon Nigel D. Heaton Ghulam J. Mufti | 2006 | Gastroenterology2006，，7： | 1 |
| 3 | Stat6-Deficient Mice Develop Airway Hyperresponsiveness and Peribronchial Fibrosis during Chronic Fungal Asthma显示文摘 | Kate Blease Jane M. Schuh Claudia Jakubzick Nicholas W. Lukacs Steven L. Kunkel Bharat H. Joshi Raj K. Puri Mark H. Kaplan Cory M. Hogaboam | 2002 | The American Journal of Pathology2002，，2： | 1 |
| 4 | Myeoplasma infections growing cattle显示文摘 | Nicholas RAJ Baker S Ayling RD | 2000 | Cattle Practice2000，8，： | 1 |
| 5 | An experimental vac-cine for calf pneumonia caused by Myenplasma boris ; clinical, cultural, serological and pathological findings 显示文摘 | Nicholas RAJ Ayling RD Laszlo P | 2002 | Vaccine2002，20，： | 1 |
| 6 | Identification of Genetic Variants That Affect Histone Modifications in Human Cells显示文摘 | Graham McVicker Bryce van de Geijn Jacob F. Degner Carolyn E. Cain Nicholas E. Banovich Anil Raj Noah Lewellen Marsha Myrthil Yoav Gilad Jonathan K. Pritchard | 2013 | Science2013，，6159： | 1 |
| 7 | The Impact of Targeted Molecular Therapies on the Level of Renal Cell Carcinoma Vena Caval Tumor Thrombus显示文摘 | Nicholas G. Cost Scott E. Delacroix Joshua P. Sleeper Paul J. Smith Ramy F. Youssef Brian F. Chapin Jose A. Karam Stephen Culp E. Jason Abel James Brugarolas Ganesh V. Raj Arthur I. Sagalowsky Christopher G. Wood Vitaly Margulis | 2011 | European Urology2011，，： | 1 |
| 8 | Serological comparisons of avian reoviruses 显示文摘 | Wood GW Nicholas RAJ Hebert CN | 1980 | J Comp Pathol1980，90，： | 1 |
| 9 | Mycoplasma in fec-tions in growing cattle显示文摘 | Nicholas RAJ Baker S Ayling R D | 2000 | Cattle Practice2000，8，： | 1 |
| 10 | Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study显示文摘Herbal medicines are popular natural medicines that have been used for decades.The use of alternative medicines continues to expand rapidly across the world.The World Health Organization suggests that quality assessment of natural medicines is essential for any therapeutic or health care applications,as their therapeutic potential varies between different geographic origins,plant species,and varieties.Classification of herbal medicines based on a limited number of secondary metabolites is not an ideal approach.Their quality should be considered based on a complete metabolic profile,as their pharmacological activity is not due to a few specific secondary metabolites but rather a larger group of bioactive compounds.A holistic and integrative approach using rapid and nondestructive analytical strategies for the screening of herbal medicines is required for robust characterization.In this study,a rapid and effective quality assessment system for geographical traceability,species,and variety-specific authenticity of the widely used natural medicines turmeric,Ocimum,and Withania somnifera was investigated using Fourier transform near-infrared(FT-NIR)spectroscopy-based metabolic fingerprinting.Four different geographical origins of turmeric,five different Ocimum species,and three different varieties of roots and leaves of Withania somnifera were studied with the aid of machine learning approaches.Extremely good discrimination(R^(2)>0.98,Q^(2)>0.97,and accuracy=1.0)with sensitivity and specificity of 100%was achieved using this metabolic fingerprinting strategy.Our study demonstrated that FT-NIR-based rapid metabolic fingerprinting can be used as a robust analytical method to authenticate several important medicinal herbs. | Samreen Khan Abhishek Kumar Rai Anjali Singh Saudan Singh Basant Kumar Dubey Raj Kishori Lal Arvind Singh Negi Nicholas Birse Prabodh Kumar Trivedi Christopher T.Elliott Ratnasekhar Ch | 2023 | Journal of Pharmaceutical Analysis2023，13，9： | 0 |
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