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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | Inflammation and Alzheimer’s disease显示文摘 | Haruhiko Akiyama Steven Barger Scott Barnum Bonnie Bradt Joachim Bauer Greg M Cole Neil R Cooper Piet Eikelenboom Mark Emmerling Berndt L Fiebich Caleb E Finch Sally Frautschy W.S.T Griffin Harald Hampel Michael Hull Gary Landreth Lih–Fen Lue Robert Mrak | 2000 | Neurobiology of Aging2000，，3： | 2 |
| 3 | Treatment of cerebral vasospasm with biocompatible controlled-release systems for intraeranial drug delivery 显示文摘 | Omeis I Neil J A Murali R Abrahams J M | 2008 | Neurosurgery2008，63，6： | 1 |
| 4 | The value of the world’s ecosystemservices and natural capita1显示文摘 | Costanza R Arge R Groot R Farberk S Grasso M HannonB Limburg K Naeem S O’Neil R Paruelo J Raskin R Suttonkk P &Belt M | 1997 | Nature1997，387，： | 1 |
| 5 | Receptor-mediated gene delivery to human peripheral blood mononuclear cells using anti-CD3 antibody coupled to polyethylenimine显示文摘 | O'NEIL M M KENNEDY C A BARTON R W | 2001 | Gene Therapy2001，，8： | 1 |
| 6 | Continuously deforming finite elements for the solution of parabolic problems,with and without plase change显示文摘 | O' Neil T M | 1981 | Int J Numer Methods Eng1981，17，： | 1 |
| 7 | Simultaneous nitrification and denitrification in aerobic chemostat cultures of Thiosphaera pantotroph Appl显示文摘 | ROBERTSON L A VAN NEIL E W J TORREMANS R A M | 1988 | Environ Mcrobiol1988，54，11： | 1 |
| 8 | Power-aware data retrieval protocols for indexed broadcast parallel channels显示文摘 | Ali R H Angela M Neil O | 2006 | Pervasive and Mobile Computing2006，2，1： | 1 |
| 9 | Zea mays Annexins Modulate Cytosolic Free Ca^sup 2+^ and Generate a Ca^sup 2+^-Permeable Conductance(W)显示文摘 | Laohavisit Anuphon Mortimer Jennifer C Demidchik Vadim Coxon Katy M Stancombe Matthew A Macpherson Neil Brownlee Colin Hofmann Andreas Webb Alex A R Miedema Henk Battey Nicholas H Davies Julia M | 2009 | Plant Cell2009，，2： | 1 |
| 10 | Oxygen gain analysis for proton exchange membrane fuel ceils 显示文摘 | O'Neil K Meyers J P Darling R M Perry M L | 2012 | International Journal of Hydrogen Energy2012，37，： | 1 |
| 11 | Postoperative analgesic effects of celecoxb or rofecoxib after spinal Iusion surgery显示文摘 | Scott S Reuben M D Neil R C | 2000 | Anelsth Analg2000，9，： | 1 |
| 12 | Inflammation and Alzheimer’s disease显示文摘 | Haruhiko Akiyama Steven Barger Scott Barnum Bonnie Bradt Joachim Bauer Greg M Cole Neil R Cooper Piet Eikelenboom Mark Emmerling Berndt L Fiebich Caleb E Finch Sally Frautschy W.S.T Griffin Harald Hampel Michael Hull Gary Landreth Lih–Fen Lue Robert Mrak | 2000 | Neurobiology of Aging2000，，3： | 1 |
| 13 | An independent effect of parental lipids on the offspring lipid levels in a cohort of adolescents with type 1 diabetes显示文摘 | M Loredana Marcovecchio Paivi H Tossavainen James JN Heywood R Neil Dalton David B Dunger | 2012 | Pediatr Diabetes2012，，6： | 1 |
| 14 | Inflammation and Alzheimer’s disease显示文摘 | Haruhiko Akiyama Steven Barger Scott Barnum Bonnie Bradt Joachim Bauer Greg M Cole Neil R Cooper Piet Eikelenboom Mark Emmerling Berndt L Fiebich Caleb E Finch Sally Frautschy W.S.T Griffin Harald Hampel Michael Hull Gary Landreth Lih–Fen Lue Robert Mrak | 2000 | Neurobiology of Aging2000，，3： | 1 |
| 15 | Identification of an up- take hydrogenase required for hydrogen-dependent reduc- tion of Fe( Ⅲ ) and other electron acceptors by Geobacter sulfurreducens显示文摘 | Coppi M V O'Neil R A Lovley D R | 2004 | Journal of Bacteriology2004，186，10： | 1 |
| 16 | Simultaneous Nitrification and Denitrification in Aerobic Chemostat Cultures Cultures of Thiosphaera Pantotroph显示文摘 | ROBERTSON L A VAN NEIL E W J TORREMANS R A M | 1988 | Appl Environ Mcrobiol1988，54，11： | 1 |
| 17 | Innovations in chemotherapy for metastatic colorectal cancer: an update of recent clinical trials 显示文摘 | O'NEIL B H GOLDBERG R M | 2008 | Oneologist2008，13，10： | 1 |
| 18 | The relationship between the quantum yield of photosynthesis electron transport and quenching of chlorophyll fluorescence 显示文摘 | Bernard G Jean M B Neil R B | 1989 | Biochem biophys acta1989，990，1： | 1 |
| 19 | Shark Depredation Rates in Pelagic Longline Fisheries:A Case Study from the Northwest Atlantic显示文摘 | Mac Neil M A Carlson J K Beerkircher L R | 2009 | ICES Journal of Marine Science2009，，4： | 1 |
| 20 | Histopathology of 'hole-in-the-head' disease in the Nile Tilapia, Oreochromis niloticus显示文摘 | MORRISON C M NEIL D O WRIGHT J R | 2007 | Aquaculture2007，273，4： | 1 |
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