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| 1 | Chlorogenic acid loaded chitosan nanoparticles with sustained release property,retained antioxidant activity and enhanced bioavailability显示文摘In this study,chlorogenic acid(CGA),a phenolic compound widely distributed in fruits and vegetables,was encapsulated into chitosan nanoparticles by ionic gelation method.The particles exhibited the size and zeta potential of 210 nm and 33 mV respectively.A regular,spherical shaped distribution of nanoparticles was observed through scanning electron microscopy(SEM)and the success of entrapment was confirmed by FTIR analysis.The encapsulation efficiency of CGA was at about 59%with the loading efficiency of 5.2%.In vitro ABTS assay indicated that the radical scavenging activity of CAG was retained in the nanostructure and further,the release kinetics study revealed the burst release of 69%CGA from nanoparticles at the end of 100th hours.Pharmacokinetic analysis in rats showed a lower level of Cmax,longer Tmax,longer MRT,larger AUC0et and AUC0e∞for the CGA nanoparticles compared to free CGA.Collectively,these results suggest that the synthesised nanoparticle with sustained release property can therefore ease the fortification of food-matrices targeted for health benefits through effective delivery of CGA in body. | Ilaiyaraja Nallamuthu Aishwarya Devi Farhath Khanum | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，3： | 7 |
| 2 | Preparation and characterization of nanocrystaUite size cuprous oxide 显示文摘 | PRAKASH I MURALIDHARAN P NALLAMUTHU N | 2007 | Materials Research Bulletin2007，42，： | 1 |
| 3 | Dimensional changes of alginate dental impression materials 显示文摘 | Nallamuthu N Braden M Patel MP | 2006 | J Mater Sci Mater Med2006，17，12： | 1 |
| 4 | Dimensional changes of alginate dental impression materials 显示文摘 | Nallamuthu N Braden M Patel MP | 2006 | J Mater Sci Mater Med2006，17，12： | 1 |
| 5 | Hy- draulics of vertical slot fishways 显示文摘 | Nallamuthu Rajaratnam Gary Van der Vinne Christos Katopodis | 1986 | Journal of Hydraulic Engineer- ing1986，112，10： | 1 |
| 6 | LDA Measurements in Open Channel显示文摘 | Peter M. Steffler Nallamuthu Rajaratnam Allan W. Peterson | 1985 | Journal of Hydraulic Engineering1985，，1： | 1 |
| 7 | Hydraulics of vertical slot fishways显示文摘 | Nallamuthu Rajaratnam Gary Van der Vinne Christos Katopodis | 1986 | Journal of Hydraulic Engineering1986，112，10： | 1 |
| 8 | Preparation and characterization of nanocrystallite size cuprous oxide 显示文摘 | Prakash I Muralidharan P Nallamuthu N Venkateswarlu M | 2007 | Materials Research Bulletin2007，42，： | 1 |
| 9 | Turbulence Structure of Hydraulic Jumps of Low Froude Numbers显示文摘 | Liu Minnan Rajaratnam Nallamuthu Zhu D Z | 2004 | Journal of Hydraulic Engineering2004，130，6： | 1 |
| 10 | Mean flow and turbulence structure in vertical slot fishway 显示文摘 | Liu Minnan Nallamuthu R David Z Zhu 2006 | 2006 | Journal of Hydraulics Engineering2006，132，8： | 1 |
| 11 | Structure of Flow in Hydraulic Jumps 显示文摘 | Dejiang Long Nallamuthu Rajaratnam Peter M | 1991 | Journal of Hydraulic Research1991，29，2： | 1 |
| 12 | Hydraulics of vertical slot fishways 显示文摘 | Nallamuthu Rajaratnam Gary Van der Vinne Christos Katopo- dis 1986 | 1986 | Journal of Hydraulic Engineering1986，112，10： | 1 |
| 13 | Hydraulics of vertical slot fishways显示文摘 | Nallamuthu Rajaratnam Gary Van der Vinne Christos Katopodis | 1986 | Journal of Hydraulic Engineering1986，112，10： | 1 |
| 14 | Effect of hydroalcoholic extract of aegle marmelos fruit on radical scavenging activity and exercise-endurance capacity in mice 显示文摘 | NALLAMUTHU I TAMATAM A KHANUM F | 2014 | Pharm bio2014，52，5： | 1 |
| 15 | Influence of Sr-doping on Various Properties of Barium Hydrogen Phosphate (BHP) Crystals显示文摘 | Nallamuthu D Selvarajan P Freeda T H | 2010 | International Journal of Pure and Applied Physics2010，6，： | 1 |
| 16 | Studies on Various Properties of Pure and Li-doped Barium Hydrogen Phosphate (BHP) Single Crystals显示文摘 | Nallamuthu D Selvarajan P Freeda T H | 2010 | Physica B2010，405，： | 1 |
| 17 | Hydraulics of vertical slot fishways 显示文摘 | Nallamuthu Rajaratnam Gary Van der Vinne Christos Katopodis | 1956 | Journal of Hydraulic Engineering1956，112，10： | 1 |
| 18 | Mean flow and turbulence structure in vertical slot fishway 显示文摘 | LIU Minnan Nallamuthu R David Z Zhu | 2006 | Journal of Hydraulics Engineering2006，132，8： | 1 |
| 19 | Computational investigation of vertical slurry jets in water显示文摘 | Amir Hossein Azimi David Z. Zhu Nallamuthu Rajaratnam | 2012 | International Journal of Multiphase Flow2012，，： | 1 |
| 20 | Experimental study of sand jet front in water显示文摘 | Amir Hossein Azimi David Z. Zhu Nallamuthu Rajaratnam | 2011 | International Journal of Multiphase Flow2011，，： | 1 |
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