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| 1 | Evaluation of extracts and essential oil from Callistemon viminalis leaves:Antibacterial and antioxidant activities,total phenolic and flavonoid contents显示文摘Objective:To investigate antioxidant and antibacterial activities of Callistemon viminalis(C.viminalis)leaves.Methods:The essential oil of C.viminalis leaves obtained by hydrodistillation was analyzed by GC/MS.Different extracts were tested for total phenolic and flavonoid contents and in vitro antioxidant(DPPH assay)and antibacterial(agar disc diffusion and 96-well micro-plates methods)actives.Results:Fourteen components were identified in the essential oil,representing 98.94%of the total oil.The major components were 1,8-cineole(64.53%)andα-pinene(9.69%).Leaf essential oil exhibited the highest antioxidant activity of(88.60±1.51)%comparable to gallic acid,a standard compound[(80.00±2.12)%].Additionally,the biggest zone of inhibitions against the studied bacterial strains was observed by the essential oil when compared to the standard antibiotic(tetracycline).The crude methanol extract and ethyl acetate fraction had a significant antibacterial activity against the tested bacterial strains.Conclusions:It can be suggested that C.viminalis is a great potential source of antibacterial and antioxidant compounds useful for new antimicrobial drugs from the natural basis.The present study revealed that the essential oil as well as the methanol extracts and ethyl acetate fraction of C.viminalis leaves exhibited highly significant antibacterial activity against the tested bacterial strains. | Mohamed ZM Salem Hayssam M Ali Nader A El-Shanhorey Ahmed Abdel-Megeed | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，10： | 14 |
| 2 | 非高密度脂蛋白胆固醇、载脂蛋白A-I及B100、标准脂质测量、脂质比值以及CRP作为女性心血管病危险因素的临床用途显示文摘背景:关于不同脂质测定、非高密度脂蛋白胆固醇(non-HDL-C)、脂质比值、载脂蛋白和C-反应蛋白(CRP)的临床应用,现行心血管危险检测指南仍有争议。
目的:直接比较总胆固醇(totalcholesterol,TC)、低密度脂蛋白胆固醇(LDL-C)、HDL-C、non-HDL-C、载脂蛋白A-I(apoA-I)及B100(apoB100)、高敏C-反应蛋白(高敏CRP)以及TC与HDL-C、LDL-C与HDL-C、apoB100与apoA-I、apoB100与HDL-C比值,在妇女作为将来心血管事件预测指标的临床用途。
设计、地点及参试者:于15 632例起始健康美国妇女进行的前瞻性队列研究。1992年11月至1995年7月人组时年龄≥45岁(4分位范围48~59岁)。所有参试者均经10年随访,观察将来心血管事件的发生情况。
主要观测指标:按照各项生化指标不同基线值而确定的首次主要心血管事件(n=4 764)的风险比(hazard ratios,HRs)及95%可信区间(confidence intervals,CIs)。
结果:在校正年龄、吸烟状况、血压、糖尿病及体重指数后,测量结果在最高5分位者将来发生心血管事件的风险比LDL-C为1.62(95%CI,1.17~2.25),apoA-I为1.75(95%CI,1.30~2.38),TC为2.08(95%CI,1.45~2.97),HDL-C为2.32(95%CI,1.64~3.33),apoB100为2.50(95%CI,1.68~3.72),non-HDL-C为2.51(95%CI,1.69~3.72),高敏CRP为2.98(95%CI,1.90~4.67)(P<0.001,趋势贯穿所有5分位)。脂质比值风险比,apoBl00与apoA-I为3.01(95%CI,2.01~4.50),LDL-C与HDL-C为3.18(95%CI,2.12~4.75),apoB100与HDL-C为3.56(95%CI,2.31~5.47),TC与HDL-C为3.81(95%CI,2.47~5.86)(P<0.001,趋势贯穿所有5分位)。高敏CRP与脂质参数的相关系数范围为-0.33到0.15,以CRP<1、1~3和>3 ms/L为临床分割点,可对每项脂质测量及脂质比值水平增加提供预后危险信息。
结论:non-HDL-C以及TC与HDL-C比值对将来心血管事件的预测效果与载脂蛋白相同或者更好。校正年龄、血压、吸烟、糖尿病和肥胖后,高敏CRP提供的预后信息超越各项脂质测量。 | Paul M Ridker Nader Rifai Nancy R.Cook Gary Bradwin Julie E Buring 徐成斌(译) | 2006 | 美国医学会杂志(中文版)2006，25，3： | 3 |
| 3 | Comparative induction of controlled circulation by magnesium and remifentanil in spine surgery显示文摘AIM: To evaluate the efficacy of magnesium sulfate(MGS) in comparison with remifentanil for induction of relative hypotension in posterior fusion of spine(PSF).METHODS: In this randomized clinical trial, 40 patients with the American Society of Anesthesiologists Ⅰ and Ⅱ physical status undergoing lumbar PSF were randomized to receive remifentanil(REM) 0.15 μg/kg or MGS 50 mg/kg for controlled hypotension. The administering anesthesiologist was blinded to the medication. Continuous infusion was maintained at a fixed volume rate to deliver precalculated doses of either study drugs. All other aspects of anesthesia and surgery were similar in the two groups. The target mean arterial pressure(MAP) range used in this study was 60-70 mm Hg. In the course of surgery, the hemodynamic variables, volumeof blood loss, urine output, fluid intake and surgeon's satisfaction were recorded. Data was analyzed with SPSS version 13.0 and P values less than 0.05 were considered significant.RESULTS: Twenty patients in the MGS group and 19 patients in the REM group were studied. There was no difference between the two groups in the hemodynamic variables, blood loss, urine output, fluid requirement and surgeon's satisfaction for exposure. The target MAP was achieved in 75% of Mg and 58% of remifentanil groups. Although a higher number of patients in the REM group required nitroglycerin(42.1%) to reach the target MAP than those in the MGS group(25%), this difference was not statistically significant(P = 0.32).CONCLUSION: Our findings showed that in patients undergoing lumbar PSF surgery, remifentanil and MGS have a similar hypotensive effect and comparable amount of blood loss without any significant adverse effects. | Mohammad R Ghodraty Mohammad M Homaee Kourosh Farazmehr Ali R Nikzad-Jamnani Masoud Soleymani-Dodaran Ali R Pournajafian Nader D Nader | 2014 | World Journal of Orthopedics2014，5，1： | 3 |
| 4 | High sensitivity C reactive protein: a novel and promising marker of coronary heart disease显示文摘 | Nader R Paul M | 2001 | Clin Chem2001，47，3： | 1 |
| 5 | Redundancy of Structural Systems with and Without Maintenance : An Approach Based on Lifetime Functions显示文摘 | Nader M O Dan M F | 2010 | Reliability Engineering and System Safety2010，95，5： | 1 |
| 6 | Comparison of C - reactive protein and low - density lipoprotein cholesterol levels in the prediction of first cardiovascular events 显示文摘 | Ridker Paul M Nader Rifai | 2002 | N Engl J Med2002，347，： | 1 |
| 7 | Fungiciddal and herbicidal activities of berberine related alkaloids显示文摘 | Iwasa K Moriyasu M Nader B | 2000 | Biosci Biotechnol Biochem2000，64，9： | 1 |
| 8 | Suspension Cable Design of the New San Francisco-Oakland Bay Bridge显示文摘 | SUN J MANZANAREZ R NADER M | 2014 | Journal of Bridge Engineering2014，9，1： | 1 |
| 9 | Investigating the five facet mindfulness questionnaire (FFMQ):construction of a short form and evidence of a two-factor higher order structure of mindfulness显示文摘 | ULRICH S TRAN TOBIAS M GLUCK INGO W NADER | 2013 | Journal of Clinical Psychology2013，69，9： | 1 |
| 10 | High-sensitivity C-reactive protein:A novel and promising marker of coronary heart disease显示文摘 | Nader Rifai Paul M Ridker | 2001 | Clin Chem2001，47，： | 1 |
| 11 | High-sensitivity C-reactive protein:A novel and promising marker of coronary heart disease显示文摘 | Nader Rifai Paul M Ridker | 2001 | Clin Chem2001，47，： | 1 |
| 12 | Sex hormone-binding globulin gene expression in the liver:drugs and the metabolic syndrome显示文摘 | Pugeat M Nader N Hogeveen K | | 0，，01： | 1 |
| 13 | High - sensitivity C - reaction protein: a novel and promising maker of coronary heart disease 显示文摘 | Nader Rifai Paul M Ridker | 2001 | Clin Chem2001，47，： | 1 |
| 14 | Synthesis and characterization of silicone-modified vinyl acetate-acrylic emulsion copolymers显示文摘 | Hamid J N Shadpour M Nader M | 2006 | Progress in Organic Coatings2006，55，4： | 1 |
| 15 | Clinical efficacy of automated high-sensitivity C-reactive protein assay显示文摘 | Nader R Russell P Paul M | 1999 | Clin Chem1999，12，12： | 1 |
| 16 | Effect of perorallyad ministered Lactobacillus macrophage activation in mice 显示文摘 | Perdigon G Nader de Macias M E Alvarez S | 1986 | Infect Immun1986，53，： | 1 |
| 17 | Novel approach for multicriteria optimization of life-cycle preventive and essential maintenance of deteriorating structures 显示文摘 | Nader M Okasha Dan M Frangopol | 2010 | Journal of Structural Engineering2010，136，8： | 1 |
| 18 | Optic canal in-volvement in tuberculum sellae meningiomas:influenceon approach,recurrence,and visual recovery显示文摘 | Mahmoud M Nader R Al-Mefty O | 2010 | Neu-rosurgery2010，67，3： | 1 |
| 19 | Homeostasis and consumer behavior across cultures 显示文摘 | Parker Philip M and Nader T Tavassoli | 2000 | International Journal of Research in Marketing2000，17，： | 1 |
| 20 | High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease显示文摘 | Nader Rifai Paul M Ridker | 2001 | Clin Chem2001，47，： | 1 |
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