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| 1 | Laparoscopic distal pancreatectomy: Up-to-date and literature review显示文摘Pancreatic surgery represents one of the most challenging areas in digestive surgery. In recent years, an increasing number of laparoscopic pancreatic procedures have been performed and laparoscopic distal pancreatectomy (LDP) has gained world-wide acceptance because it does not require anastomosis or other reconstruction. To date, English literature reports more than 300 papers focusing on LDP, but only 6% included more than 30 patients. Literature review confirms that LDP is a feasible and safe procedure in patients with benign or low grade malignancies. Decreased blood loss and morbidity, early recovery and shorter hospital stay may be the main advantages. Several concerns still exist for laparoscopic pancreatic adenocarcinoma excision. The individual surgeon determines the technical conduction of LDP, with or without spleen preservation; currently robotic pancreatic surgery has gained diffu- sion. Additional researches are necessary to determine the best technique to improve the procedure results. | Maurizio Iacobone Marilisa Citton Donato Nitti | 2012 | World Journal of Gastroenterology2012，18，38： | 8 |
| 2 | Telomeres,telomerase and colorectal cancer显示文摘Colorectal cancer(CRC)is the third most common cancer worldwide and,despite improved treatments,is still an important cause of cancer-related deaths.CRC encompasses a complex of diseases arising from a multistep process of genetic and epigenetic events.Besides heterogeneity in the molecular and biological features of CRC,chromosomal instability is a hallmark of cancer and cancer cells may also circumvent replicative senescence and acquire the ability to sustain unlimited proliferation.Telomere/telomerase interplay is an important mechanism involved in both genomic stability and cellular replicative potential,and its dysfunction plays a key role in the oncogenetic process.The erosion of telomeres,mainly because of cell proliferation,may be accelerated by specific alterations in the genes involved in CRC,such as APC and MSH2.Although there is general agreement that the shortening of telomeres plays a role in the early steps of CRC carcinogenesis by promoting chromosomal instability,the prognostic role of telomere length in CRC is still under debate.The activation of telomerase reverse transcriptase(TERT),the catalytic component of the telomerase complex,allows cancer cells to grow indefinitely by maintaining the length of the telomeres,thus favouring tumour formation/progression.Several studies indicate that TERT increases with disease progression,and most studies suggest that telomerase is a useful prognostic factor.Plasma TERT mRNA may also be a promising marker for the minimally invasive monitoring of disease progression and response to therapy. | Roberta Bertorelle Enrica Rampazzo Salvatore Pucciarelli Donato Nitti Anita De Rossi | 2014 | World Journal of Gastroenterology2014，20，8： | 5 |
| 3 | Precancerous lesions in the stomach: From biology to clinical patient management显示文摘 | Massimo Rugge Lisette G. Capelle Rocco Cappellesso Donato Nitti Ernst J. Kuipers | 2013 | Best Practice & Research Clinical Gastroenterology2013，，2： | 4 |
| 4 | Telomere-Specific Reverse Transcriptase (hTERT) and Cell-free RNA in Plasma as Predictors of Pathologic Tumor Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy显示文摘 | Salvatore Pucciarelli Enrica Rampazzo Marta Briarava Isacco Maretto Marco Agostini Maura Digito Sonia Keppel Maria Friso Sara Lonardi Antonino Paoli Claudia Mescoli Donato Nitti Anita Rossi | 2012 | Annals of Surgical Oncology2012，，9： | 2 |
| 5 | 男性原发性膀胱颈梗阻的诊断与治疗显示文摘Primary bladder neck obstruction has more recently been recognized as a relatively common explanation of voiding dysfunction in men less than 50 years of age. Often complaints range from urgency, frequency, urge incontinence and nocturia to decreased force of stream, hesitancy, dribbling, and intermittency. Occasionally, patients even present with complete retention or elevated post-void residuals, bladder stones, diverticula, or recurrent urinary tract infections. Most commonly patients have had symptoms and signs for years prior to diagnosis and have been treated with multiple medications including extended periods of antibiotics. A diagnosis of pelvic pain, non-bacterial prostatitis, and somatoform/psychogenic disorders is also a common label in men with this disorder. A primary challenge for the physician/urologist is the accurate diagnosis of this disorder with a particular diagnostic modality, videourodynamics. With a continued awareness and high level of suspicion that primary bladder neck obstruction may be present in young men with voiding dysfunction perhaps a timely diagnosis can be reached without the unnecessary empirical therapies of prolonged antibiotic courses, biofeedback, and the like. | Victor W. Nitti 陈朝晖 | 2005 | 临床泌尿外科杂志2005，20，3： | 2 |
| 6 | A Multicentric Western Analysis of Prognostic Factors in Advanced, Node-Negative Gastric Cancer Patients显示文摘 | Gian Luca Baiocchi Guido A. Tiberio Anna Maria Minicozzi Paolo Morgagni Daniele Marrelli Lorenzo Bruno Fausto Rosa Alberto Marchet Arianna Coniglio Luca Saragoni Marco Veltri Fabio Pacelli Franco Roviello Donato Nitti Stefano M. Giulini Giovanni De Manzon | 2010 | Annals of Surgery2010，，1： | 2 |
| 7 | Cancer resistance to type ]I topoi- somerase inhibitors显示文摘 | Pilati P Nitti D Mocellin S | 2012 | Curr Med Chem2012，19，23： | 1 |
| 8 | DIAGNOSING BLADDER OUTLET OBSTRUCTION IN WOMEN显示文摘 | VICTOR W. NITTI LE MAI TU JORDAN GITLIN | 1999 | The Journal of Urology1999，，5： | 1 |
| 9 | TNF and cancer: the two sides of the coin 显示文摘 | Mocellin S Nitti D | 2008 | Front Biosci2008，13，： | 1 |
| 10 | The copper-iron connection: hereditary aceruloplasminemia显示文摘 | NITTIS T GITLIN J D | 2002 | Semin Hematol2002，39，： | 1 |
| 11 | Amino acid sequence and disulfide-bridge pattern of three y-thionins from Sorghum bicolor显示文摘 | Nitti G Orru S Bloch C Jr | 1995 | Eur J Biochem1995，228，： | 1 |
| 12 | Efficacy, safety and tolerability of fesoterodine for overactive bladder syndrome显示文摘 | Nitti VW Dmochowski R Sand PK | 2007 | J Urol2007，178，6： | 1 |
| 13 | Extended lymphadenectomy(D2)in patients with early gastric cancer显示文摘 | Nitti D Marchet A Mammano E | 2005 | Eur J Surg Oncol2005，31，8： | 1 |
| 14 | Comparison of diagnostic criteria for female bladder outlet obstruction显示文摘 | AkikwalaTV Fleischman N Nitti VW | 2006 | Journal of Urology2006，，05： | 1 |
| 15 | Comparison of diagnostic criteria for female bladder outlet obstruction 显示文摘 | Akikwala TV Fleischman N Nitti VW | 2006 | J Urol2006，176，5： | 1 |
| 16 | Fluoropyrimidine-HAI(hepatic arterial infusion)versus systemic chemotherapy(SCT)for unresectable liver metastases from colorectal cancer显示文摘 | Mocellin S Pasquali S Nitti D | 2009 | Cochrane Database Syst Rev2009，8，00： | 1 |
| 17 | Heme oxygenase-l-derived bilirubin protects endothelial cells against high glucose-induced damage 显示文摘 | He M Nitti M Piras S | 2015 | Free radical biology & medicine2015，89，： | 1 |
| 18 | Efficacy of the 133-adre- noceptor agonist mirabegron for the treatment of overactive blad- der by severity of incontinence at baseline: a post hoe analysis of pooled data from three randomised phase 3 trials 显示文摘 | Chapple C Khullar V Nitti VW | 2015 | Eur Urol2015，67，： | 1 |
| 19 | Prognostic value of subclassification of T2 turnouts in patients with gastric cancer显示文摘 | Nitti D Marchet A Mocellin S | 2009 | Br J Surg2009，96，4： | 1 |
| 20 | Dissecting tumor responsive- ness to immunotherapy: the experience of peptide-based melanoma vaccines 显示文摘 | Mocellin S Rossi CR Nitti D | 2003 | Biochim Biophys Acta2003，1653，2： | 1 |
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