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| 1 | 板液压成形及无模充液拉深技术显示文摘板液压成形技术是液压成形技术中重要的一类 ,广泛地应用于宇航、汽车等工业领域。近年来由于新材料和复杂几何形状零件的不断出现 ,更加突出此种技术的关键性。本文就板液压成形技术原理、数值模拟技术和分类进行了研究 ,探讨了此种技术将来的发展 ,介绍了基于板液压成形技术的无模充液拉深技术 ,利用实验和数值模拟技术对此技术进行了分析 ,验证了此项技术的可行性 。 | 朗利辉 Joachim Danckert Karl Brian Nielsen 张士宏 康达昌 | 2002 | 塑性工程学报2002，9，4： | 49 |
| 2 | 管件内高压成形及其在汽车工业中的应用现状显示文摘利用管件内高压成形技术成形的工件具有质量轻、刚度好、装配零件少、后续装配工序少等诸多优点 ,在国外该项技术已被广泛地运用到汽车、宇航领域中。介绍并探讨了管件内高压成形技术的原理、优点。 | 郎利辉 苑世剑 王仲仁 王小松 Joachim Danckert Karl Brian Nielsen | 2004 | 中国机械工程2004，15，3： | 35 |
| 3 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012，30，2： | 32 |
| 4 | Inflammatory pathways of importance for management of inflammatory bowel disease显示文摘Inflammatory bowel disease(IBD)is a group of chronic disorders of the gastrointestinal tract comprising Crohn’s disease(CD)and ulcerative colitis(UC).Their etiologies are unknown,but they are characterised by an imbalanced production of pro-inflammatory mediators,e.g.,tumor necrosis factor(TNF)-α,as well as increased recruitment of leukocytes to the site of inflammation.Advantages in understanding the role of the inflammatory pathways in IBD and an inadequate response to conventional therapy in a large portion of patients,has over the last two decades lead to new therapies which includes the TNF inhibitors(TNFi),designed to target and neutralise the effect of TNF-α.TNFi have shown to be efficient in treating moderate to severe CD and UC.However,convenient alternative therapeutics targeting other immune pathways are needed for patients with IBD refractory to conventional therapy including TNFi.Indeed,several therapeutics are currently under development,and have shown success in clinical trials.These include antibodies targeting and neutralising interleukin-12/23,small pharmacologic Janus kinase inhibitors designed to block intracellular signaling of several pro-inflammatory cytokines,antibodies targeting integrins,and small anti-adhesion molecules that block adhesion between leukocytes and the intestinal vascular endothelium,reducing their infiltration into the inflamed mucosa.In this review we have elucidated the major signaling pathways of clinical importance for IBD therapy and highlighted the new promising therapies available.As stated in this paper several new treatment options are under development for the treatment of CD and UC,however,no drug fits all patients.Hence,optimisations of treatment regimens are warranted for the benefit of the patients either through biomarker establishment or other rationales to maximise the effect of the broad range of mode-of-actions of the present and future drugs in IBD. | Jannie Pedersen Mehmet Coskun Christoffer Soendergaard Mohammad Salem Ole Haagen Nielsen | 2014 | World Journal of Gastroenterology2014，20，1： | 28 |
| 5 | EFFECTS OF SPECIFIED BLANK SIZE ON BODY WRINKLING DURING HYDRODYNAMIC DEEP DRAWING OF TAPERED RECTANGULAR BOX显示文摘In this paper, the forming features of tapered rectangular box during hydrodynamic deep drawing are studied by means of FEM.The effect rules of square blank corner corner amount on body wrinkling are recognized and corresponding methods are discussed. At last, the results of FEM are verified by experi- ment. | L. H. Lang, D. C. Kang, S. H. Zhang, Z. R. Wang, S. J. Yuan, K. B. Nielsen and J. Dancket 1) Department of Materials Engineering, Harbin Institute of Technology, Harbin 150001, China 2) Aalberg University, Denmark | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 21 |
| 6 | Key players in pancreatic cancer-stroma interaction: cancer-associated fibroblasts, endothelial and inflammatory cells显示文摘Pancreatic cancer(PC) is the most aggressive type of common cancers, and in 2014, nearly 40000 patients died from the disease in the United States. Pancreatic ductal adenocarcinoma, which accounts for the majority of PC cases, is characterized by an intense stromal desmoplastic reaction surrounding the cancer cells. Cancer-associated fibroblasts(CAFs) are the main effector cells in the desmoplastic reaction, and pancreatic stellate cells are the most important source of CAFs. However, other important components of the PC stroma are inflammatory cells and endothelial cells. The aim of this review is to describe the complex interplay between PC cells and the cellular and noncellular components of the tumour stroma. Published data have indicated that the desmoplastic stroma protects PC cells against chemotherapy and radiation therapy and that it might promote the proliferation and migration of PC cells. However, in animal studies, experimental depletion of the desmoplastic stroma and CAFs has led to more aggressive cancers. Hence, the precise role of the tumour stroma in PC remains to be elucidated. However, it is likely that a contextdependent therapeutic modification, rather than pure depletion, of the PC stroma holds potential for the development of new treatment strategies for PC patients. | Michael Friberg Bruun Nielsen Michael Bau Mortensen Sonke Detlefsen | 2016 | World Journal of Gastroenterology2016，22，9： | 20 |
| 7 | miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis显示文摘AIM:To use microarray-based miRNA profiling of colonic mucosal biopsies from patients with ulcerative colitis (UC), Crohn's disease (CD), and controls in order to identify new potential miRNA biomarkers in inflammatory bowel disease. METHODS:Colonic mucosal pinch biopsies from the descending part were obtained endoscopically from patients with active UC or CD, quiescent UC or CD, as well as healthy controls. Total RNA was isolated and miRNA expression assessed using the miRNA microarray Geniom Biochip miRNA Homo sapiens (Febit GmbH, Heidelberg, Germany). Data analysis was carried out by principal component analysis and projection to latent structure-discriminant analysis using the SIMCA-P+12 software package (Umetrics, Umea, Sweden). The microarray data were subsequently validated by quantitative real-time polymerase chain reaction (qPCR) performed on colonic tissue samples from active UC patients (n = 20), patients with quiescent UC (n = 19), and healthy controls (n = 20). The qPCR results were analyzed with Mann-WhitneyU test.In silico prediction analysis were performed to identify potential miRNA target genes and the predicted miRNA targets were then compared with all UC associated susceptibility genes reported in the literature. RESULTS:The colonic mucosal miRNA transcriptome differs significantly between UC and controls, UC and CD, as well as between UC patients with mucosal inflammation and those without. However, no clear differences in the transcriptome of patients with CD and controls were found. The miRNAs with the strongest differential power were identified (miR-20b, miR-99a, miR-203, miR-26b, and miR-98) and found to be upregulated more than a 10-fold in active UC as compared to quiescent UC, CD, and controls. Two miRNAs, miR-125b-1* and let-7e*, were up-regulated more than 5-fold in quiescent UC compared to active UC, CD, and controls. Four of the seven miRNAs (miR-20b, miR-98, miR-125b-1*, and let-7e*) were validated by qPCR and found to be specifically upregulated in patients with UC. Usingin silico analysis we found several predicted pro-inflammatory target genes involved in various pathways, such as mitogen-activated protein kinase and cytokine signaling, which are both key signaling pathways in UC.CONCLUSION:The present study provides the first evidence that miR-20b, miR-98, miR-125b-1*, and let7e* are deregulated in patients with UC. The level of these miRNAs may serve as new potential biomarkers for this chronic disease. | Mehmet Coskun Jacob Tveiten Bjerrum Jakob Benedict Seidelin Jesper Thorvald Troelsen JΦrgen Olsen Ole Haagen Nielsen | 2013 | World Journal of Gastroenterology2013，19，27： | 19 |
| 8 | 肺炎链球菌耐药基因ermB、mefA、tetM与转座子整合酶基因intTn的检测显示文摘目的研究耐药基因ermB、mefA、tetM与转座子整合酶基因intTn在携带肺炎链球菌的北京儿童中分布特点。方法对185株呼吸道感染患儿鼻咽部分离的肺炎链球菌进行以下检测:Etest、琼脂稀释或纸片扩散法测定对大环内酯类、四环素、β内酰胺类及头孢类等15种抗生素的药物敏感性。PCR检测大环内酯类耐药基因ermB和mefA,四环素耐药基因tetM以及转座子Tn1545的整合酶基因intTn。结果185株肺炎链球菌的药敏结果显示,对红霉素、克林霉素、四环素和复方磺胺甲基异唑的耐药率较高,分别为78.9%、76.2%、86.0%和78.7%,对阿莫西林克拉维酸、头孢克洛、头孢曲松和头孢呋辛耐药率较低,分别为2.2%、15.5%、2.8%和14.1%。所有红霉素耐药株均检出ermB和或mefA,其中79.5%为ermB阳性,17.8%为ermB和mefA同时阳性,2.7%为mefA阳性。tetM基因在分离株中的阳性率是87%,四环素耐药组的tetM基因携带率是96.9%,高于敏感组(26.9%)。四环素耐药株的红霉素耐药率(90.0%)亦高于敏感株组(11.5%)。87.6%的肺炎链球菌存在intTn基因,intTn基因阳性组的红霉素、四环素、氯霉素、复方磺胺甲基异唑和环丙沙星的耐药率较intTn基因阴性组高。分离株最常见的基因组合是intTn+tetM+ermB,占58.4%。结论北京地区呼吸道感染儿童鼻咽部肺炎链球菌耐大环内酯类抗生素的主要原因是ermB编码的23SrRNA甲基化酶致靶位改变。tetM基因编码蛋白质的核糖体保护作用,是肺炎链球菌四环素耐药的重要机制。接合性转座子Tn1545的存在与菌株的红霉素和四环素耐药关系密切,可能是肺炎链球菌多重耐药的重要机制之一。 | 杨慧 杨永弘 Elisabet Nielsen 俞桑洁 袁林 王咏红 沈叙庄 | 2005 | 中华微生物学和免疫学杂志2005，25，8： | 19 |
| 9 | MicroRNAs in inflammatory bowel disease-pathogenesis,diagnostics and therapeutics显示文摘The pathogenesis of inflammatory bowel disease (IBD) is complex and largely unknown. Until recently, research has focused on the study of protein regulators in inflammation to reveal the cellular and molecular networks in the pathogenesis of IBD. However, in the last few years, new and promising insights have been generated from studies describing an association between an altered expression of a specific class of non-coding RNAs, called microRNAs (miRs or miRNAs) and IBD. The short (approximately 22 nucleotides), endogenous, single-stranded RNAs are evolutionary conserved inanimals and plants, and regulate specific target mRNAs at the post-transcriptional level. MiRNAs are involved in several biological processes, including development, cell differentiation, proliferation and apoptosis. Furthermore, it is estimated that miRNAs may be responsible for regulating the expression of nearly one-third of the genes in the human genome. Thus, miRNA deregulation often results in an impaired cellular function, and a disturbance of downstream gene regulation and signaling cascades, suggesting their implication in disease etiology. Despite the identification of more than 1900 mature human miRNAs, very little is known about their biological functions and functional targets. Recent studies have identified dysregulated miRNAs in tissue samples of IBD patients and have demonstrated similar differences in circulating miRNAs in the serum of IBD patients. Thus, there is great promise that miRNAs will aid in the early diagnosis of IBD, and in the development of personalized therapies. Here, we provide a short review of the current state-of-the-art of miRNAs in IBD pathogenesis, diagnostics and therapeutics. | Mehmet Coskun Jacob Tveiten Bjerrum Jakob Benedict Seidelin Ole Haagen Nielsen | 2012 | World Journal of Gastroenterology2012，18，34： | 18 |
| 10 | The Power of Inbreeding: NGS-Based GWAS of Rice Reveals Convergent Evolution during Rice Domestication显示文摘低范围的整个染色体的定序是为在人的染色体宽的协会研究的有效策略,由于为遗传型归罪的大参考面板的可获得性。然而,没有引用面板,这策略是否能在另外的种类被利用,是不清楚的。用模拟,我们有效地证明这条途径在象米饭(Oryza sativa L.) 那样的生来的种类是甚至更相关的,它是打电话的 haploid,允许的容易的 haplotype 构造和基于归罪的遗传型,甚至没有大参考面板的可获得性。我们在 1.5 桔牯捡獯潣祰的平均深度从农业米饭微型核心收集的美国部门与描绘得好的显型定序 203 个米饭变化吗?? | Hongru Wang Xun Xu Filipe Garrett Vieira Yunhua Xiao Zhikang Li Jun Wang Rasmus Nielsen Chengcai Chu | 2016 | Molecular Plant2016，9，7： | 17 |
| 11 | GABA_A受体药理学研究进展显示文摘GABAA受体为配体闸门离子通道超家族成员之一。本文简要概述了GABA受体的提出和分类。重点介绍了国内外有关GABAA 受体的药理学研究情况 ,包括GABAA 受体的结构 ,作用于GABAA 受体GABA识别位点、安定类识别位点。 | 王秀坤 Nielsen M | 2001 | 国外医学(药学分册)2001，28，1： | 17 |
| 12 | Intragenic antagonistic roles of protein and circRNA in tumorigenesis显示文摘circRNAs arise from back splicing events during mRNA processing, and when deregulated can play an active role in cancer. Here we characterize a new circRNA (circPOK) encoded by the Zbtb7a gene (also kown as POKEMON, LRF) in the context of mesenchymal tumor progression. circPOK functions as a non-coding proto-oncogenic RNA independently and antithetically to its linear transcript counterpart, which acts as a tumor suppressor by encoding the Pokemon transcription factor. We find that circPOK regulates pro-proliferative and pro-angiogenic factors by co-activation of the ILF2/3 complex. Importantly, the expression of Pokemon protein and circRNA is aberrantly uncoupled in cancer through differential post-transcriptional regulation. Thus, we identify a novel type of genetic unit, the iRegulon, that yields biochemically distinct RNA products, circular and linear, with diverse and antithetical functions. Our findings further expand the cellular repertoire towards the control of normal biological outputs, while aberrant expression of such components may underlie disease pathogenesis including cancer. | Jlenia Guarnerio Yang Zhang Giulia Cheloni Riccardo Panella Jesse Mae Katon Mark Simpson Akinobu Matsumoto Antonella Papa Cristian Loretelli Andreas Petri Sakari Kauppinen Cassandra Garbutt Gunnlaugur Petur Nielsen Vikram Deshpande Mireia Castillo-Martin Carlos Cordon-Cardo Spentzos Dimitrios John G. Clohessy Mona Batish Pier Paolo Pandolfi | 2019 | Cell Research2019，29，8： | 15 |
| 13 | 经皮肝穿刺射频消融治疗包膜下肝肿瘤与非包膜下肝肿瘤效用与安全性的前瞻性对照研究显示文摘目的评价经皮肝穿刺射频(RF)消融治疗包膜下肝肿瘤的效用与安全性。方法本研究经伦理委员会批准,所有受试者都签署了知情同意书。18t例病人(男79例,女102例,年龄36~85岁)的361个原发或继发(转移的)肝肿瘤进行了超声引导下的经皮RF消融治疗。44例病人有1个或1个以上包膜下肿瘤(组1),137病人仅有非包膜下肿瘤(组2)。总共80个包膜下结节和281个非包膜下结节。RF消融后1个月进行增强CT扫描评价消融的完整性。如果CT显示肿瘤残留,则再次进行RF消融。所有1次或2次RF消融治疗后的病人,每3个月进行CT或增强US进行监控。 | S. Sartori P. Tombesi F. Macario I. Nielsen D. Tassinari M. Catellani 高莉(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 12 |
| 14 | 中国的双顺差、日本经验及失衡调整显示文摘 | 卢锋 Naoyuki Yoshino Erik Nielsen Wolfgang Munchau 张文才 | 2006 | 国际经济评论2006，，5： | 12 |
| 15 | Chinese life cycle impact assessment factors显示文摘The methodological basis and procedures for determination of Chinese normalization references and weighting factors according to the EDIP\|method is described. According to Chinese industrial development intensity and population density, China was divided into three regions and the normalization references for each region were calculated on the basis of an inventory of all of the region’s environmental emissions in 1990. The normalization reference was determined as the total environmental impact potential for the area in question in 1990 (EP(j) 90 ) divided by the population. The weighting factor was determined as the normalization reference (ER(j) 90 ) divided by society’s target contribution in the year 2000 based on Chinese political reduction plans, ER(j) T2000 . This paper presents and discuss results obtained for eight different environmental impact categories relevant for China: global warming, stratospheric ozone depletion, acidification, nutrient enrichment, photochemical ozone formation and generation of bulk waste, hazardous waste and slag and ashes. | Yang, J.-X. Nielsen, P.H. | 2001 | Journal of Environmental Sciences2001，13，2： | 11 |
| 16 | Pathophysiology of chronic pancreatitis显示文摘Chronic pancreatitis(CP)is an inflammatory disease of the pancreas characterized by progressive fibrotic destruction of the pancreatic secretory parenchyma.Despite the heterogeneity in pathogenesis and involved risk factors,processes such as necrosis/apoptosis,inflammation or duct obstruction are involved.This fibrosing process ultimately leads to progressive loss of the lobular morphology and structure of the pancreas,deformation of the large ducts and severe changes in the arrangement and composition of the islets.These conditions lead to irreversible morphological and structural changes resulting in impairment of both exocrine and endocrine functions.The prevalence of the disease is largely dependent on culture and geography.The etiological risk-factors associated with CP are multiple and involve both genetic and environmental factors.Throughout this review the M-ANNHEIM classification system will be used,comprising a detailed description of risk factors such as:alcohol-consumption,nicotineconsumption,nutritional factors,hereditary factors,efferent duct factors,immunological factors and miscellaneous and rare metabolic factors.Increased knowledge of the different etiological factors may encourage the use of further advanced diagnostic tools,which potentially will help clinicians to diagnose CP at an earlier stage.However,in view of the multi factorial disease and the complex clinical picture,it is not surprising that treatment of patients with CP is challenging and often unsuccessful. | Christina Brock Lecia Mφller Nielsen Dina Lelic Asbjφrn Mohr Drewes | 2013 | World Journal of Gastroenterology2013，19，42： | 11 |
| 17 | 二穗短柄草幼胚再生体系及农杆菌介导转化的初步研究显示文摘以二穗短柄草3个品系BDR018,BD21,BD21-3的幼胚为外植体,研究了幼胚大小对胚性愈伤组织诱导和再生的影响。采用携带gus和bar基因双元表达载体(pDM805)的根癌农杆菌菌株AGL1对BDR018品系的幼胚愈伤组织进行了遗传转化。本实验探讨了影响幼胚愈伤组织诱导再生及遗传转化的几个因素。结果发现,幼胚大小介于0.5~1.0mm之间的愈伤组织诱导率最高。随愈伤组织年龄的增加,BDR018,BD21,BD21-3愈伤组织的再生率下降,白化率上升。愈伤组织年龄在5~8周范围内转化效率较高,平均转化效率为38.5%。真空处理5min和0.01%的Silwet L-77处理均可提高转化效率。对转化植株进行GUS基因化学组织检测和PCR鉴定,初步证明外源基因已整合再生植株基因组中。 | 吴雪莉 刘金星 Klaus K Nielsen 杨志民 高彩霞 | 2010 | 草业学报2010，19，5： | 11 |
| 18 | Efficient unidirectional polarization-controlled excitation of surface plasmon polaritons显示文摘Efficient excitation of surface plasmon polaritons(SPPs)remains one of the most challenging issues in areas of plasmonics related to information communication technologies.In particular,combining high SPP excitation efficiency and acceptance of any polarization of incident light appeared to be impossible to attain due to the polarized nature of SPPs.Here we demonstrate plasmonic couplers that represent arrays of gap SPP resonators producing upon reflection two orthogonal phase gradients in respective linear polarizations of incident radiation.These couplers are thereby capable of efficiently converting incident radiation with arbitrary polarization into SPPs that propagate in orthogonal directions dictated by the phase gradients.Fabricated couplers operate at telecom wavelengths and feature the coupling efficiency of,25%for either of two linear polarizations of incident radiation and directivity of SPP excitation exceeding 100.We further demonstrate that an individual wavelength-sized unit cell,representing a meta-scatterer,can also be used for efficient and polarization sensitive SPP excitation in compact plasmonics circuits. | Anders Pors Michael G Nielsen Thomas Bernardin Jean-Claude Weeber Sergey I Bozhevolnyi | 2014 | Light(Science & Applications)2014，3，1： | 11 |
| 19 | 从丹麦牙科教育看我国口腔医学教育的发展显示文摘丹麦现行的口腔医学教育体系和模式特点体现在教师启发和动员学生主动思考的作用强 ,学生的参与性强 ,提问和辩论突出。另外学生早期接触临床实践 ,从第二年即开始临床见习 ,并随年级的增长逐步增加诊断、预防、治疗和定期口腔护理 ,最终独立接诊。各学科教学效果并非单纯考试决定 ,而是由包括学校行政、教师、学生代表等的专业委员会来综合评估 。 | 王勤涛 张玉梅 Lene Rindal Nielsen | 2003 | 牙体牙髓牙周病学杂志2003，13，8： | 11 |
| 20 | Modulation of Gut Microbiota in Pathological States显示文摘人类微生态是寄居在人体中的微生物聚集体,且主要存在于胃肠道(GIT)中。肠道微生态随着人体发育而演化,并在人类健康和疾病中起着重要作用。近年来,由于微生态会影响宿主代谢、生理学和免疫系统发育,而且微生态紊乱可能导致许多疾病,其越来越受到人们的关注。肠道微生态可能与恶性肿瘤有一定联系,如胃癌和结直肠癌;也可能与其他一些疾病有关,如非酒精性脂肪肝(NAFLD)、被称为工业化世界'生活方式疾病'的肥胖和糖尿病、冠心病以及中枢神经系统紊乱。虽然分子技术革命为我们更准确地研究肠道微生态提供了必要的工具,但是我们需要更精确地阐明其与某些人类疾病病理变化的关系,明确微生态在不同疾病中的作用是新的治疗策略发展的基础。本文概述了肠道微生态对人类健康的重要影响以及调整肠道菌群结构的潜在用途,如菌群移植用于治疗耐药艰难梭菌(C.difficile)的感染。通过微生态干预调整肠道区域以改善人类健康的概念虽刚刚兴起,但其治疗意义显著。因此,抑制有害菌、促进有益菌可能会保护人类健康,并且这些努力将为探索发展更加合理的治疗方案打下基础。 | Yulan Wang BaohongWang Junfang wu xiangyang Jiang Huiru Tang Ole H. Nielsen | 2017 | Engineering2017，3，1： | 9 |
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