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| 1 | Mid-infrared dual-comb spectroscopy with electro-optic modulators显示文摘Absorption spectroscopy of fundamental ro-vibrational transitions in the mid-infrared region provides a powerful tool for studying the structure and dynamics of molecules in the gas phase and for sensitive and quantitative gas sensing.Laser frequency combs permit novel approaches to perform broadband molecular spectroscopy.Multiplex dual-comb spectroscopy without moving parts can achieve particularly high speed,sensitivity and resolution.However,achieving Doppler-limited resolution in the mid-infrared still requires overcoming instrumental challenges.Here we demonstrate a new approach based on difference-frequency generation of frequency-agile near-infrared frequency combs that are produced using electro-optic modulators.The combs have a remarkably flat intensity distribution,and their positions and line spacings can be freely selected by simply dialing a knob.Using the proposed technique,we record,in the 3-μm region,Doppler-limited absorption spectra with resolved comb lines within milliseconds,and precise molecular line parameters are retrieved.Our technique holds promise for fast and sensitive time-resolved studies of,for example,trace gases. | Ming Yan Pei-Ling Luo Kana Iwakuni Guy Millot Theodor W Hänsch Nathalie Picqué | 2017 | Light(Science & Applications)2017,6,1: | 5 |
| 2 | Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients With Refractory Crohn’s Disease显示文摘 | Pierre Desreumaux Arnaud Foussat Matthieu Allez Laurent Beaugerie Xavier Hébuterne Yoram Bouhnik Maria Nachury Valérie Brun Hervé Bastian Nathalie Belmonte Michel Ticchioni Agnès Duchange Patricia Morel–Mandrino Virginie Neveu Nathalie Clerget–Chossat Mig | 2012 | Gastroenterology2012,,5: | 4 |
| 3 | Effect of sustained virological response on long-term clinical outcome in 113 patients with compensated hepatitis C-related cirrhosis treated by interferon alpha and ribavirin显示文摘AIM:To assess the long-term clinical benefit of sustained virological response(SVR)in patients with hepatitis C virus(HCV)cirrhosis treated by antiviral therapy using mostly ribavirin plus interferon either standard or pegylated.METHODS:One hundred and thirteen patients with uncomplicated HCV biopsy-proven cirrhosis,treated by at least one course of antiviral treatment ≥ 3 mo and followed ≥ 30 mo were included.The occurrence of clinical events hepatocellular carcinoma(HCC),decompensation and death was compared in SVR and non SVR patients.RESULTS:Seventy eight patients received bitherapy and 63 had repeat treatments.SVR was achieved in 37 patients(33%).During a mean follow-up of 7.7 years,clinical events occurred more frequently in non SVR than in SVR patients,with a significant difference for HCC(24/76 vs 1/37,P = 0.01).No SVR patient died while 20/76 non-SVR did(P = 0.002),mainly in relation to HCC(45%).CONCLUSION:In patients with HCV-related cirrhosis,SVR is associated with a significant decrease in the incidence of HCC and mortality during a follow-up period of 7.7 years.This result is a strong argument to perform and repeat antiviral treatments in patients with compensated cirrhosis. | Roland El Braks Nathalie Ganne-Carrié Hélène Fontaine Jacques Paries Véronique Grando-Lemaire Michel Beaugrand Stanislas Pol Jean-Claude Trinchet | 2007 | World Journal of Gastroenterology2007,13,42: | 3 |
| 4 | High cardiovascular risk in severely obese young children and adolescents显示文摘 | Nathalie M A van Emmerik Carry M Renders Marije van de Veer Stef van Buuren Olga H van der Baan-Slootweg Joana E Kist-van Holthe Remy A HiraSing | 2012 | Archives of Disease in Childhood2012,,9: | 2 |
| 5 | <ce:link locator='fx1'/> <ce:link locator='fx2'/> Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis显示文摘 | Rami Moucari Tarik Asselah Dominique Cazals–Hatem Hélène Voitot Nathalie Boyer Marie–Pierre Ripault Rodolphe Sobesky Michèle Martinot–Peignoux Sarah Maylin Marie–Hélène Nicolas–Chanoine Valérie Paradis Michel Vidaud Dominique Valla Pierre Bedossa Patrick | 2008 | Gastroenterology2008,,2: | 2 |
| 6 | Transcriptional Regulation of P450scc Gene Expression in the Embryonic Rodent Nervous System 显示文摘 | Fabian H Nathalie A Compagnone | 2004 | Endocrinology2004,145,2: | 1 |
| 7 | Determining Robust Impacts of Land-Use-Induced Land Cover Changes on Surface Climate over North America and Eurasia: Results from the First Set of LUCID Experiments显示文摘 | de Noblet-Ducoudré Nathalie Boisier Juan-Pablo Pitman Andy Bonan G B Brovkin V Cruz Faye Delire C Gayler V van den Hurk B J J M Lawrence P J van der Molen M K Müller C Reick C H Strengers B J Voldoire A | 2012 | EN2012,,9: | 1 |
| 8 | Antigen bias in T cell cross-priming显示文摘 | Monika C W Nathalie B Arnold H B | 2004 | Science2004,304,: | 1 |
| 9 | Treatment of Domestic Wastewater Using the Nutrient Film Technique (NFT) to Produce Horticultural Roses显示文摘 | Monnet Fabien Vaillant Nathalie H ITM I Adnane | 2002 | Water Research2002,36,14: | 1 |
| 10 | Interleukin-4 Cellular Gene Therapy and Osteoprotegerin Decrease Inflammation-Associated Bone Resorption in Collagen-Induced Arthritis显示文摘 | Nathalie Saidenberg-Kermanac’h Natacha Bessis Delphine Lemeiter Marie-Christine de Vernejoul Marie-Christophe Boissier Martine Cohen-Solal | 2004 | Journal of Clinical Immunology2004,,4: | 1 |
| 11 | Determining Robust Impacts of Land-Use-Induced Land Cover Changes on Surface Climate over North America and Eurasia: Results from the First Set of LUCID Experiments显示文摘 | de Noblet-Ducoudré Nathalie Boisier Juan-Pablo Pitman Andy Bonan G B Brovkin V Cruz Faye Delire C Gayler V van den Hurk B J J M Lawrence P J van der Molen M K Müller C Reick C H Strengers B J Voldoire A | 2012 | EN2012,,9: | 1 |
| 12 | NADH-dependent metabolism of nitric oxide in alfalfa root cultures expressing barley hemoglobin显示文摘 | Abir U. Igamberdiev Csaba Seregélyes Nathalie Manac′h Robert D. Hill | 2004 | Planta2004,,1: | 1 |
| 13 | Preparation and characterization of poly (amidoaminc) dendrimers functionalized with a rhenium carbonyl complex and PEG as new IR probes for carbonyl metallo immunoassay 显示文摘 | Jan M H Nathalie F D Michele S | 2004 | J Organometallic Chemistry2004,689,25: | 1 |
| 14 | Sucrose Metabolism in Plastids 显示文摘 | Nathalie Gerrits Stefan C H J Turk Kees P M van Dun | 2001 | Plant Physiology2001,125,2: | 1 |
| 15 | Varicella-zoster virus does not signicantly induce the cell defence mechanism mediated by the 2- 5A/RNase L pathway during显示文摘 | Nathalie D Markus R Manfred H | 2005 | Med Microbiol Immunol2005,194,6: | 1 |
| 16 | Propagation and isolation of group A coxsackieviruses in RD cells显示文摘 | Nathalie J S Helen H H Edwin H L | 1975 | J Clin Microbiol1975,3,2: | 1 |
| 17 | Gamma-glutamyl transpeptidase gene organization and expression:a comparative analysis in rat,mouse,pig and human species显示文摘 | Naima C Nathalie H Georges G | 1999 | Comparative Biochemistry and Physiology Part B1999,122,4: | 1 |
| 18 | Self- reported hypertension prevalence and income among older adults in Can- ada and the United States显示文摘 | MARKS K NATHALIE H DAVID F | 2010 | Social Science&Medicine2010,,70: | 1 |
| 19 | Biosynthesis and action of neurosteroids显示文摘 | Synthia H Mellon Lisa D Griffin Nathalie A Compagnone | 2001 | Brain Research Reviews2001,,1: | 1 |
| 20 | Enhanced copper tolerance in Silene vulgaris (Moench) garcke populations from copper mines is associated with increased transcript levels of a b-type metallothionein gene显示文摘 | NATHALIE A L M HASSINEN V H | 2001 | Plant Physiology2001,126,: | 1 |