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| 1 | Evaluation of mannitol effect in patients with acute hepatic failure and acute-on-chronic liver failure using conventional MRI,diffusion tensor imaging and in-vivo proton MR spectroscopy显示文摘AIM:To evaluate the effect of an intravenous bolus of mannitol in altering brain metabolites, brain water content, brain parenchyma volume, cerebrospinal fluid (CSF) volume and clinical signs in controls and in patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF), by comparing changes in conventional magnetic resonance imaging (MRI), in vivo proton magnetic resonance spectroscopy (PMRS) and diffusion tensor imaging (DTI) before and after its infusion.METHODS: Five patients each with ALF and ACLF in grade 3 or 4 hepatic encephalopathy and with clinical signs of raised intracranial pressure were studied along with five healthy volunteers. After baseline MRI, an intravenous bolus of 20% mannitol solution was given over 10 min in controls as well as in patients with ALF and ACLF. Repeat MRI for the same position was acquired 30 min after completing the mannitol injection. RESULTS: No statistically significant difference was observed between controls and patients with ALF and ACLF in metabolite ratios, DTI metrics and brain volume or CSF volume following 45 min of mannitol infusion. There was no change in clinical status at the end of post-mannitol imaging. CONCLUSION: The osmotic effect of mannitol did not result in significant reduction of brain water content, alteration in metabolite ratios or any change in the clinical status of these patients during or within 45 min of mannitol infusion. | Vivek A Saraswat Sona Saksena Kavindra Nath Pranav Mandal Jitesh Singh M Albert Thomas Ramkishore S Rathore Rakesh K Gupta | 2008 | World Journal of Gastroenterology2008，14，26： | 2 |
| 2 | Impact of tricuspid regurgitation on long-term survival显示文摘 | Nath J Foster E Heidenreich P A | 2004 | J Am Coll Cardid2004，43，3： | 1 |
| 3 | Permeability of the blood - brain barrier to HIV - 1 TAT显示文摘 | Banks WA Robinson SM Nath A | 2005 | Exp Neuro12005，193，： | 1 |
| 4 | Extension of shelf life of pear fruits using different packaging materials显示文摘 | Nath A Deka B Singh A | 2012 | Food Sci Technol2012，49，5： | 1 |
| 5 | 查看详情显示文摘 | Nath D C D Bandyopadhyay S Boughton P Yu A | | 0，，： | 1 |
| 6 | Optimization of oven toasting for improving crispness and other quality attributes of ready to eal potato-soy snack using response surface methodology显示文摘 | Nath A Chattopadhyay P K | 2007 | Journal of l'ood Engineering2007，80，： | 1 |
| 7 | Remedies for HIV-associated peripheral neuropathy显示文摘 | Berger JR Nath A | 2000 | Neurology2000，1354，11： | 1 |
| 8 | Synthesis and characterization of magnetic iron sulfide nanowires 显示文摘 | Nath M Choudhury A Kundu A | 2003 | Adv Mater2003，15，24： | 1 |
| 9 | Progesterone vaginal ring for con- traceptive use during lactation显示文摘 | NATH A SITRUK-WARE R | 2010 | Contraception2010，82，5： | 1 |
| 10 | fMRI- Guided transcranial magnetic stimulation reveals that the su- perior temporal sulcus is a cortical locus of the McGurk effect 显示文摘 | BEAUCHAMP M S NATH A R PASALAR S | 2010 | J Neurosci2010，30，24： | 1 |
| 11 | Modification of bent angle of mechanically formed stainless steel sheets by laser forming显示文摘 | CHAKRABORTY S S MORE H RACHERLA V NATH A K | 2015 | Journal of Materials Processing Technology2015，222，： | 1 |
| 12 | Viruses and the brain:From inflam marion to dementia显示文摘 | Wang T Rumbaugh JA Nath A | 2006 | Clin Sci2006，110，4： | 1 |
| 13 | High prevalence of moderately severe vitamin D deficiency in preterm infants显示文摘 | Dawodu A Nath R | 2011 | Pediatr Int2011，53，2： | 1 |
| 14 | Early hemodynamic changes in experiment intracerebral hemorrhage 显示文摘 | Nath FP Jenkins A Mendelow AD | 1986 | J Neurosurg1986，65，5： | 1 |
| 15 | Disruption of neurogenesis in the subventricular zone of adult mice,and in human cortical neuronal precursor cells in culture,by amyloid beta-peptide:implications for the pathogenesis of Alzheimer's disease显示文摘 | Haughey NJ Liu D Nath A | 2002 | Neuromolecular Med2002，1，2： | 1 |
| 16 | Disruption of neurogenesis by amyloid β-peptide and perturbed calcium homeostasis in models of Alzheimer's disease 显示文摘 | Haughey N J Nath A Liu D | 2002 | J Neuroehem2002，83，： | 1 |
| 17 | 查看详情显示文摘 | Nath D C D Bandyopadhyay S Yu A | | 0，，： | 1 |
| 18 | Is the mortality higher in the pulmonary vs the extrapulmonary ARDS A meta analysis显示文摘 | Agarwal R Srinivas R Nath A | | 0，，06： | 1 |
| 19 | Treatment with antisense oligonucleotide reduces the expression of type I collagen in a human-skin organ-wound model:implications for antifibrotic gene therapy显示文摘 | XIONG W HUMPHRIES A D | 2007 | Ann Plast Surg2007，59，6： | 1 |
| 20 | Oxygen consumption and oxidant stress in surviving nephrons显示文摘 | Nath KA Croat A J Hostetter TH | 1990 | Am J Physiol1990，258，： | 1 |
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