|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011，21，4： | 3 |
| 2 | Two-stage Fowler-Stephens Orchidopexy Preserving the Gobernacular Vessels and a Purely Laparoscopic Second Stage显示文摘 | Robertson S A Munro F D Mackinlay G A | 2007 | J Laparoendosc Adv Surg Tech A2007，17，1： | 1 |
| 3 | Prototypic G protein coupled receptor for the intestinotrophic factor glucagon- like peptide-2显示文摘 | Munroe DG Gupta AK Kooshesh F | 1999 | Proc Natl Acad Sci USA1999，96，： | 1 |
| 4 | The impact of NHS Di rect on the demand for out-of-hours primary and emer- gency care显示文摘 | Munro J Sampson F Nicholl J | 2005 | Br J Gen Pract2005，55，519： | 1 |
| 5 | Mammary duct ectasia in children:report of a short series and review of the literature显示文摘 | McHoney M Munro F Mackinlay G | 2011 | Early Hum Dev2011，87，8： | 1 |
| 6 | 查看详情显示文摘 | M D Reid W J Munro F De Martini | | 0，，03： | 1 |
| 7 | Mammary duct ectasia in children: report of a short series and review of the literature 显示文摘 | McHoney M Munro F Mackinlay G | 2011 | Early Hum Dev2011，87，8： | 1 |
| 8 | 查看详情显示文摘 | Landen O L Boehly T R Bradley D K Braun D G Callahan D A Celliers P M Collins G W Dewald E L Divol L Glenzer S H Hamza A Hicks D G Hoffman N Izumi N Jones O S Kirkwood R K Kyrala G A Michel P Milovich J Munro D H Nikroo A Olson R E Robey H F Spears B K Th | | 0，，： | 1 |
| 9 | Erythritol:an interpretive summary of biochemical,metabolic,toxicological and clinical data显示文摘 | Munro C Bernt W O Borzelleca J F | 1998 | Food and Chemical Toxicol1998，36，12： | 1 |
| 10 | Sucrose-derived exopolysaccharides of Streptococcus mutans V403 contribute to infectivity in endocarditis显示文摘 | MUNRO C L MACRINA F L | 1993 | Mol Microbiol1993，8，1： | 1 |
| 11 | Detection and characterization of the hemolysin genes in Aeromonas hydrophila and Aeromonas sobria by multiplex PCR显示文摘 | Wang G Clark C G Liu C Y Pucknell C Munro C K Kruk T M A C Caldeira R Woodward D L Rodgers F G | 2003 | J Clin Microbiol2003，41，3： | 1 |
| 12 | Incisional hernia following laparoscopy: a survey of the American Association of Gynecologic Laparoscopists 显示文摘 | Montz F J Holschneider C H Munro M G | 1994 | Obstet Gynecol1994，84，5： | 1 |
| 13 | Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins显示文摘 | Munroe S H Caceres J F | 1994 | EMBO J1994，13，22： | 1 |
| 14 | Erythritol: An interpretive summary of biochemical, metabolic, toxico- logical and clinical data 显示文摘 | Munro I C Bemt W O Borzelleca J F | 1998 | Food Chem Toxicology1998，36，12： | 1 |
| 15 | Collaborative vir- tual environments: digital places and spaces for interaction 显示文摘 | Churchill E F Snowdon D N Munro A J | 2002 | Educational Technology & Society2002，5，4： | 1 |
| 16 | Maximizing the entanglement of two mixed qubits显示文摘 | MUNRO W J JAMES D F V WHITE A G | 2001 | Physical Review A2001，64，3： | 1 |
| 17 | Microstructure,mechanical properties and wear of NiAlFe alloys显示文摘 | MUNROE P R GEORGE M BAKER I KENNEDY F E | 2002 | Mater Sci Eng A2002，325，： | 1 |
| 18 | Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins 显示文摘 | Mayeda A Munroe S H Caceres J F | 1994 | EMBO J1994，13，22： | 1 |
| 19 | Maximizing the Entanglement of two Mixed Qubits 显示文摘 | MUNRO W J JAMES D F V WHITE A G etal | 2001 | Phys Rev A2001，14，3： | 1 |
| 20 | Unusual tazobactam-sensitive AmpC β-lactamase from two Escherichia coli isolates显示文摘 | Babini G S Danel F Munro S D | 1998 | J Antimicrob Chemother1998，41，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员