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| 1 | Diagnosis of early gastric cancer using narrow band imaging and acetic acid显示文摘AIM: To determine whether the endoscopic findings of depressed-type early gastric cancers(EGCs) could precisely predict the histological type.METHODS: Ninety depressed-type EGCs in 72 patients were macroscopically and histologically identified. We evaluated the microvascular(MV) and mucosal surface(MS) patterns of depressed-type EGCs using magnifying endoscopy(ME) with narrow-band imaging(NBI)(NBI-ME) and ME enhanced by 1.5% acetic acid, respectively. First, depressed-type EGCs were classified according to MV pattern by NBI-ME. Subsequently, EGCs unclassified by MV pattern were classified according to MS pattern by enhanced ME(EME) images obtained from the same angle.RESULTS: We classified the depressed-type EGCs into the following 2 MV patterns using NBI-ME: a fine-network pattern that indicated differentiated adenocarcinoma(25/25, 100%) and a corkscrew pattern that likely indicated undifferentiated adenocarcinoma(18/23, 78.3%). However, 42 of the 90(46.7%) lesions could not be classified into MV patterns by NBI-ME. These unclassified lesions were then evaluated for MS patterns using EME, which classified 33(81.0%) lesions as MS patterns, diagnosed as differentiated adenocarcinoma. As a result, 76 of the 90(84.4%) lesions were matched with histological diagnoses using a combination of NBI-ME and EME.CONCLUSION: A combination of NBI-ME and EME was useful in predicting the histological type of depressedtype EGC. | Ken Matsuo Hidetoshi Takedatsu Michita Mukasa Hiroaki Sumie Hikaru Yoshida Yasutomo Watanabe Jun Akiba Keita Nakahara Osamu Tsuruta Takuji Torimura | 2015 | World Journal of Gastroenterology2015,21,4: | 9 |
| 2 | Clinical characteristics and management of gastric tube cancer with endoscopic submucosal dissection显示文摘AIM:To identify the characteristics of gastric tube cancer(GTC) and the complications associated with endoscopic submucosal dissection(ESD) for GTC.METHODS:Between 2007 and 2012,11 individualswith early gastric cancer in the reconstructed gastric tube after esophagectomy who underwent ESD in this hospital were studied.The characteristics of GTC were identified,and the complications of ESD for GTC were analyzed at three phases:preoperative,intraoperative,and postoperative.RESULTS:A total of 11 consecutive patients with 11 GTCs were selected for this study.All cases underwent en bloc resections by ESD.The median procedure time was 142 min.The average GTC diameter was 26.1 mm,and the average size of the resected lesions was 45.5 mm.The histopathological diagnosis in all cases was a differentiated adenocarcinoma.In the preoperative phase,anastomotic strictures(5/11,45%) and food residues(4/11,36.4%) in the gastric tube were the main complications.In the intraoperative phase,bleeding was observed in 5 cases(45%).The postoperative complications observed were delayed bleeding in 2 cases(18.2%) and stenosis in one case(9.1%).The case with stenosis was successfully treated using endoscopic balloon dilatation.CONCLUSION:Minor complications were frequently observed.However,all GTCs underwent en bloc resection with ESD without any serious complications.ESD is considered a useful treatment for GTC. | Michita Mukasa Hidetoshi Takedatsu Ken Matsuo Hiroaki Sumie Hikaru Yoshida Atsushi Hinosaka Yasutomo Watanabe Osamu Tsuruta Takuji Torimura | 2015 | World Journal of Gastroenterology2015,21,3: | 8 |
| 3 | Prediction of colorectal tumor grade and invasion depth through narrow-band imaging scoring显示文摘AIM To determine the usefulness of assigning narrow-band imaging(NBI) scores for predicting tumor grade and invasion depth in colorectal tumors.METHODS A total of 161 colorectal lesions were analyzed from138 patients who underwent endoscopic or surgical resection after conventional colonoscopy and magnifying endoscopy with NBI. The relationships between the surface and vascular patterns of the lesions, as visualized with NBI, and the tumor grade and depth of submucosa(SM) invasion were determined histopathologically.Scores were assigned to distinct features of the surface microstructures of tubular and papillary-type lesions.Using a multivariate analysis, a model was developed for predicting the tumor grade and depth of invasion based on NBI-finding scores.RESULTS NBI findings that correlated with a high tumor grade were associated with the 'regular/irregular'(P < 0.0001)surface patterns and the 'avascular area' pattern(P =0.0600). The vascular patterns of 'disrupted vessels'(P = 0.0714) and 'thick vessels'(P = 0.0133) but none of the surface patterns were associated with a depth of invasion of ≥ 1000 μm. In our model, a total NBIfinding score ≥ 1 was indicative of a high tumor grade(sensitivity: 0.97; specificity: 0.24), and a total NBIfinding score ≥ 9(sensitivity: 0.56; specificity: 1.0) was predictive of a SM invasion depth ≥ 1000 μm. Scores less than these cutoff values signified adenomas and a SM invasion depth < 1000 μm, respectively. Associations were also noted between selected NBI findings and tumor tissue architecture and histopathology.CONCLUSION Our multivariate statistical model for predicting tumor grades and invasion depths from NBI-finding scores may help standardize the diagnosis of colorectal lesions and inform therapeutic strategies. | Yasuhiko Maeyama Keiichi Mitsuyama Tetsuhiro Noda Shiuchiro Nagata Tsutomu Nagata Shinichiro Yoshioka Hikaru Yoshida Michita Mukasa Hiroaki Sumie Hiroshi Kawano Jun Akiba Yuko Araki Tatsuyuki Kakuma Osamu Tsuruta Takuji Torimura | 2018 | World Journal of Gastroenterology2018,24,42: | 4 |
| 4 | Separation of arenols from a high-temperature coal tar显示文摘A high-temperature coal tar collected from Xuzhou Coking Plant,Saint-Gobain Pipelines(Xuzhou) Co.,Ltd.was exhaustively extracted with petroleum ether(PE).The extract was sequentially eluted through silica gel with PE and PE/ethyl acetate(EA) mixed solvents(volume ratio 2:1) to afford two eluted fractions.The extract and eluted fractions were analyzed with gas chromatography/mass spectrometry.In total,14 arenols were detected,including phenol,cresols,xylenols,fluorenols,phenanthren-3-ol and pyren-1-ol. | Ting Yao Zhi-Min Zong ZheWen Robert Mukasa Nan-Hua Yuan Xian-Yong Wei | 2012 | International Journal of Mining Science and Technology2012,22,2: | 3 |
| 5 | Comparison of phenolic compositions between common and tartary buckwheat ( Fagopyrum ) sprouts显示文摘 | Sun-Ju Kim I.S.M. Zaidul Tatsuro Suzuki Yuji Mukasa Naoto Hashimoto Sigenobu Takigawa Takahiro Noda Chie Matsuura-Endo Hiroaki Yamauchi | 2008 | Food Chemistry2008,,4: | 2 |
| 6 | Self-Powered Wearable Biosensors显示文摘CONSPECTUS:Wearable biosensors hold the potential of revolutionizing personalized healthcare and telemedicine.Advances in chemical sensing,flexible materials,and scalable manufacturing techniques now allow wearables to detect key physiological indicators such as temperature,vital signs,body motion,and molecular biomarkers.With these systems operating on the skin,they enable continuous and noninvasive disease diagnosis and health monitoring.Such complex devices,however,require suitable power sources in order to realize their full capacity.Emerging wearable energy harvesters are attractive for addressing the challenges of a wearable power supply.These harvesters convert various types of ambient energy sources(e.g.,biomechanical energy,biochemical energy,and solar energy)into electricity.In some circumstances,the harvested electrical signals can directly be used for active sensing of physiological parameters.On the other hand,single or hybrid wearable energy harvesters,when integrated with power management circuits and energy storage devices,could power additional biosensors as well as signal processing and data transmission electronics.Selfpowered sensor systems operate continuously and sustainably without an external power supply are promising candidates in the next generation of wearable electronics and the Internet of Things.This Account highlights recent progress in self-powered wearable sensors toward personalized healthcare,covering biosensors,energy harvesters,energy storage,and power supply strategies.The Account begins with an introduction of our wearable biosensors toward an epidermal detection of physiological information.Advances in structural and material innovations enable wearable systems to measure both biophysical and biochemical indicators conformably,accurately,and continuously.We then discuss emerging technologies in wearable energy harvesting,classified according to their capability to scavenge energy from various sources.These include examples of using energy harvesters themselves as active biosensors.Through seamless integration and efficient power management,self-powered wireless wearable sensor systems allow real-time data acquisition,processing,and transmission for health monitoring.The final section of the Account covers the existing challenges and new opportunities for self-powered wearable sensors in health monitoring and human−machine interfaces toward personalized and precision medicine. | Yu Song Daniel Mukasa Haixia Zhang Wei Gao | 2021 | Accounts of Materials Research2021,2,3: | 2 |
| 7 | Comparison of phenoliccomposi tions between common and tartary buckwheat (Fagopyrum) sprouts显示文摘 | Kim S J Zaidul I S M Suzuki T Mukasa Y Hashimoto N Takigawa S Noda T Endo M C and Yamauchi H | | 0,,04: | 1 |
| 8 | Developmental plasticity of Thl7 and Treg cells显示文摘 | Lee YK Mukasa R Hatton RD | 2009 | Curr Opin Immunol2009,21,3: | 1 |
| 9 | Prevalence of malignant tu- mors and adenomatous lesions detected by ultrasonographic screening in patients with autoimmune thyroid disease显示文摘 | Mukasa K Neh J Y Kunii Y | 2011 | Thy- roid2011,21,1: | 1 |
| 10 | Sequence Divergence of Four Soilborne Sugarbeet-Infecting Viruses显示文摘 | Lennefors B L Savenkov E I Mukasa S B Valkonen J P T | 2005 | Virus Genes2005,31,: | 1 |
| 11 | 显示文摘 | Sayama K Mukasa K Abe R | 2001 | Chem Commun2001,23,8: | 1 |
| 12 | Developmental plasticity of Th17 and Treg cells显示文摘 | Yun Kyung Lee Ryuta Mukasa Robin D Hatton Casey T Weaver | 2009 | Current Opinion in Immunology2009,,3: | 1 |
| 13 | Suitability of rice-tartary buck- wheat for crossbreeding and for utilization of rutin 显示文摘 | Mukasa Y Suzuki T Honda Y | 2009 | Jpn Agr Res Ouart2009,43,3: | 1 |
| 14 | Interactions be- tween a crinivirus, an ipomovirus and a potyvirus in coinfected sweet potato plants 显示文摘 | Mukasa S B Rubaihayo P R Valkonen J P T | 2006 | Plant Pathology2006,55,3: | 1 |
| 15 | Developmental plasticity of Thl7 and Treg cells 显示文摘 | Lee Y K Mukasa R Hatton R D | 2009 | Curr Opin Immunol2009,21,3: | 1 |
| 16 | 显示文摘 | Sayama K Mukasa K Arakawa H | 2001 | Chem Commun2001,23,8: | 1 |
| 17 | 显示文摘 | Sayama K Mukasa K Arakawa H | 2002 | Photochem Photobiol2002,148,13: | 1 |
| 18 | Characterization of peroxidase in buckwheat seed显示文摘 | Suzuki T Honda Y Mukasa Y | 2006 | Phytoehemistry2006,,67: | 1 |
| 19 | Sweetpotato viruses: 15 years of progress on understanding and managing complex diseases显示文摘 | Clark C A Davis J A Abad J A Cuellar W J Fuentes S Kreuze J F Gibson R W Mukasa S Tugume A K Tairo F Valkonen J P T | 2012 | Plant Disease2012,96,2: | 1 |
| 20 | Developmental plasticity of Th17 and Treg ceils 显示文摘 | Lee YK Mukasa R Hatton RD | 2009 | Curr Opin Immunol2009,21,3: | 1 |