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| 1 | Diabetes and cancer:Looking at the multiligand/RAGE axis显示文摘The association between diabetes and hyperglycemia and the associated increased risk of several solid and hematologic malignancies has been the subject of investigation for many years.Although the association is not fully understood,current knowledge clearly indicates that diabetes may influence malignant cell transformation by several mechanisms,including hyperinsulinemia,hyperglycemia and chronic inflammation.In this context,the receptor for advanced glycation end-products (RAGE) has emerged as a focal point in its contribution to malignant transformation and tumor growth.We high-light how RAGE,once activated,as it manifests itself in conditions such as diabetes or hyperglycemia,is able to continuously bring about an inflammatory milieu,thus supporting the contribution of chronic inflammation to the development of malignancies. | Armando Rojas Ileana González Erik Morales Ramón Pérez-Castro Jacqueline Romero Héctor Figueroa | 2011 | World Journal of Diabetes2011，2，7： | 11 |
| 2 | Mortality and morbidity in patients with atrial fibrillation and liver cirrhosis显示文摘BACKGROUND Atrial fibrillation(AF)is the most common cardiac arrhythmia encountered in clinical practice.However,the outcomes associated with AF in hospitalized patients with liver cirrhosis are unknown.AIM To determine the outcomes of hospitalized patients with liver cirrhosis and AF.METHODS In this study,we examined morbidity and mortality of patients with concomitant AF and liver cirrhosis from the National Inpatient Sample database,the largest publicly available inpatient healthcare database in the United States.RESULTS A total of 696937 patients with liver cirrhosis were included,45745 of whom had concomitant AF(6.6%).Liver cirrhosis patients with AF had higher rates of inhospital mortality(12.6%vs 10.3%,P<0.001),clinical stroke(1.6%vs 1.1%,P<0.001),and acute kidney injury(28.2%vs 25.1%,P<0.001),and less gastrointestinal bleeding(4.4%vs 5.1%,P<0.001)and blood transfusion(22.5%vs 23.8%,P<0.001)compared with those who did not have the arrhythmia.In addition,they had a longer length of stay(8±10 d vs 7±8 d,P<0.001)and higher hospitalization costs(20720±33210$vs 16272±24166$,P<0.001).CONCLUSION In subjects with liver cirrhosis,AF is associated with higher rates of inpatient mortality,stroke,and acute kidney injury compared to those who do not have the cardiac arrhythmia. | Yousef H Darrat Aiman Smer Claude-Samy Elayi Gustavo X Morales Fahad Alqahtani Mohamad Alkhouli John Catanzaro Jignesh Shah Mohsin Salih | 2020 | World Journal of Cardiology2020，12，7： | 2 |
| 3 | Combinatorial optimization of group key management显示文摘 | M Eltoweissy M H Heydari L Morales | 2004 | Jotlmal of Network and Systems Management: Special Issue on Network Security2004，12，1： | 1 |
| 4 | Combinatorial optimization of key management in group eommunieations显示文摘 | Eltoweisy M Heydari H Morales L | 2004 | Journal ol Network and Systems Management2004，12，1： | 1 |
| 5 | Addition of ultralow dose naloxone to postoperative morphine PCA:unchanged analgesia and opioid requirement but decreased incidence of opioid side effects显示文摘 | Cepeda M S Alvarez H Morales 0 | 2004 | Pain2004，107，12： | 1 |
| 6 | Asymmetric reduction of aromatic ketones显示文摘 | Morales H R Perez-Juarez M Cuellar L | 1984 | Synth Commun1984，14，13： | 1 |
| 7 | Evidence that wakefulness and REM sleep are controlled by a GABAergic pontine mechanism 显示文摘 | XI M C MORALES F R CHASE M H | 1999 | J Neurophysiol1999，82，4： | 1 |
| 8 | Development and use of quality of care indicators for obstetric care in women with preeclampsia,severe preeclampsia,and severe morbidity显示文摘 | Perez C R Morales H R Doubova S V | 2007 | Hypertens Pregnancy2007，26，3： | 1 |
| 9 | Cold and ambienr deck storage prior to processing as a critical control point for patulin accumulation 显示文摘 | Morales H Marin S Centelles X | 2007 | International Journal of Food Microbiology2007，116，2： | 1 |
| 10 | Continuous-specimen-flow,high-throughput,1-hour tissue processing:a system for rapid diagnostic tissue preparation显示文摘 | Morales AR Essenfeld H Essenfeld E | 2002 | Arch Pathol Lab Med2002，126，5： | 1 |
| 11 | Variational inequalities for φ-pseudocontractive mappings显示文摘 | Claudio H Morales | | 0，，02： | 1 |
| 12 | Surjectivity theorems for multl-valued mappings of accretive type显示文摘 | Morales C H | 1985 | Comment Math Univ Carolin1985，26，2： | 1 |
| 13 | Contrast/Noise ratio on conventional MRI and choline/creatine ratio on proton MRI spectroscopy accurately discriminate low-grade from high-grade cerebral gliomas显示文摘 | Fayed N Morales H Modrego PJ | 2006 | Acad Radiol2006，13，： | 1 |
| 14 | Liquid chromatographic and electrophoretic eharacterisation of extracellular beta-glucosidase of Pleurotus ostreatus grown in organic waste 显示文摘 | Morals H Ramos C Matos N | 2002 | J Chmmatogr B2002，770，： | 1 |
| 15 | The Mann process for perturbed m-accretive operators in Banach spaces显示文摘 | Morales C H Jung J S | 2001 | Nonlinear Anal2001，46，： | 1 |
| 16 | Identification of potential cell-surfaceproteins in Candida albicans and investigation of the role of aputative cell-surface glycosidase in adhesion and virulence显示文摘 | Alberti-Segui C Morales A J Xing H Kessler M M Willins DA Weinstock K G | 2004 | Yeast2004，21，： | 1 |
| 17 | GABAergic mechanisms in the pedunculopontine tegmental nucleus of the cat promote active ( REM) sleep 显示文摘 | TORTEROLO P MORALES F R CHASE M H | 2002 | Brain Res2002，944，12： | 1 |
| 18 | Effect of biocontrol ageuts Candida sake and Pantoea agglomerans on Penicillium expansum growth and patulin accumulation in apples显示文摘 | MORALES H SANCHIS V USALL J | | 0，，1： | 1 |
| 19 | Suppression ofcoastal heath vegetation by Eucalyptus baxteri 显示文摘 | MORAL R D WILUS R J ASHTON D H | 1978 | AustralianJournal of Botany1978，26，2： | 1 |
| 20 | Combinatorial Optimization of Key Management in Group Communications显示文摘 | Eltoweissy M Heydari H Morales L | 2004 | Journal of Network and Systems Management2004，12，1： | 1 |
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