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| 1 | Direct ex vivo analysis of dendritic cells in patients with hepatocellular carcinoma显示文摘瞄准:与肝细胞癌(HCC ) 从病人分析树枝状的房间(DC ) 的显型和功能以便在这疾病理解他们的角色。方法:骨髓的的树枝状的房间在 HCC 病人的外部血被枚举。从外部血的天真、刺激的骨髓的的树枝状的房间上的 CD80, CD83, CD86 和 HLA 医生表示被分析。骨髓的的树枝状的房间从外部血被孤立,他们的功能被测试。吞噬作用用 FITC 葡聚糖祷告被分析,肽特殊刺激,在多形核白细胞 dI:dC 之上刺激 allogeneic T 房间和 cytokines 的分泌物的能力被测试。结果:骨髓的的树枝状的房间与 HCC 在病人被减少。在 CD80, CD83, CD86 和 HLA 医生表示的差别都没从 HCC 病人和健康控制在天真、刺激的骨髓的的树枝状的房间上被发现。肽 specific T 房间的正常吞噬作用或刺激与一个损害 allo-stimulatory 能力和减少的 IL-12 分泌物相对照被观察。结论:在病人的 mDCs 的损害 IL-12 生产能导致建议指导治疗可以提高的那 IL-12 的天真的 T 房间的一个损害 stimulatory 能力在 HCC 病人的肿瘤 specific 免疫者回答。 | Lars A Ormandy Anatol Frber Tobias Cantz Susanne Petrykowska Heiner Wedemeyer Monique Hrning Frank Lehner Michael P Manns Firouzeh Korangy Tim F Greten | 2006 | World Journal of Gastroenterology2006，12，20： | 12 |
| 2 | A specific prebiotic oligosaccharide mixture stimulates delayed-type hypersensitivity in a murine influenza vaccination model显示文摘 | ARJAN P VOS MONIQUE HAARMAN AMRA BUCO | 2006 | Int Immunopharmacol2006，6，8： | 1 |
| 3 | Conditional autoimmnity mediated by human natural anti-FceRIa autoantibodies?显示文摘 | Michael P Jana M Monique V | 2001 | The FASEB Journal2001，15，12： | 1 |
| 4 | Application of a multi-sulfonamide biosensor immunoassay for the detection of sulfadiazine andsulfamethoxazole residues in broiler serum and its use as a predictor of the levels in edible tissue显示文摘 | WILLEM H MONIQUE B P URPO L | 2005 | Anal Chim Acta2005，552，12： | 1 |
| 5 | 'Non-Q wave',myocardial infarction:Aspecific entity显示文摘 | Xavier Ag Monique P Alain L | 1989 | Am Heart J1989，，： | 1 |
| 6 | Application of a multi- sulfonamide biosensor immunoassay for the detection of sulfadiazine and sulfamethoxazole residues in broiler serum and its use as a predictor of the levels in edible tissue显示文摘 | WILLEM H MONIQUE B P URPO L | 2005 | Anal Chim Acta2005，552，： | 1 |
| 7 | Hypoxia inducible factor 1 gene ( HIF -1 ct ) splice variants: Potential prognostic biomarkers in breast cancer显示文摘 | Jean P D Nathalie B Monique S | 2010 | BMC Medicine2010，8，1： | 1 |
| 8 | Studies on new polymeric bio materials with tunable hydrophilicity,and their possible utility in corneal repair surgery显示文摘 | Monique J B Pijpers A P | 2002 | Biomaterials2002，23，4： | 1 |
| 9 | Structure-function analysis of multidrug transporters in Lactococcus lactis 显示文摘 | Heudrik W van V Monique P | 1999 | Biochimicaet Biophysica Acta1999，1461，： | 1 |
| 10 | Prepartive separation of anthocyanins by gradient elution centrifugal partition chromatography显示文摘 | Renault J H Thépenier P Monique Z H | 1997 | J Chromatography A1997，763，： | 1 |
| 11 | Optimal portfolio for a small investor in a market model with discontinuous prices显示文摘 | Monique J P Monique P | 1990 | Applied Math- ematiee and Optmization1990，22，： | 1 |
| 12 | Fullerene is a powerful antioxidant in vivo with no acute or subacute toxicity显示文摘 | Najla G Monique P Michelle H | | 0，，12： | 1 |
| 13 | Fast urinary screening of oligosaccharidoses by MALDI-TOF/TOF mass spectrometry显示文摘 | Laurent B Monique P Céline C | 2014 | Orphanet Journal of Rare Diseases2014，，9： | 1 |
| 14 | Hypoxia inducible factor 1gene(HIF-1α)splice variants:Potential prognostic biomarkers in breast cancer显示文摘 | Jean P D Nathalie B Monique S | 2010 | BMC Medicine2010，8，1： | 1 |
| 15 | Choroidal neovascularization as a late complication of hyperparathyroidism显示文摘 | Salomon Y Monique GS Michel P | 1998 | Am J Ophthalmol1998，126，： | 1 |
| 16 | Active tuberculosis in inflammatory bowel disease patients under treatment from an endemic area in Latin America显示文摘BACKGROUND There has been an increase in cases of inflammatory bowel disease(IBD)in recent years.There is also greater access and availability of immunosuppressive and biological agents,which increase the risk of opportunistic infection despite improving the quality of life and promoting mucosal healing.Tuberculosis(TB)remains a public health problem,and it has a high incidence in several countries.Therefore,knowledge of the risk of developing TB in patients with IBD is important.AIM To evaluate the risk of active TB in patients with IBD under treatment from an endemic area in Latin America.METHODS A standard questionnaire included demographic variables,clinical aspects of IBD disease,history of active TB during treatment,active TB characteristics and evolution,initial screening and results and time from the start of anti-tumor necrosis factor alpha(TNFα)to TB development.RESULTS Azathioprine,anti-TNFα and the combination of these two drugs were associated with a higher risk of active TB incidence.The TNFα blockers increased the relative risk of developing active TB compared to other treatments.All four multivariable models showed that the use of TNFα blockers alone or in combination with azathioprine was an important risk factor for the incidence of active TB.After adjustment for sex,age,type of IBD and latent TB,anti-TNFα with azathioprine increased the relative risk to 17.8 times more than conventional treatment.Late TB,which was diagnosed 3 mo after the start of anti-TNFα,was the most frequent.CONCLUSION Treatment with anti-TNFα increased the risk of active TB in IBD patients from an endemic area in Latin America.This risk was increased when anti-TNFα was combined with azathioprine.The time from the beginning of the treatment to the active TB diagnosis suggests a new TB infection. | Flora Maria Lorenzo Fortes Ney Boa Sorte Victor D Mariano Laila D Andrade Fernanda A Oliveira Monique CA Santos Claudia Ivanilda N dos Santos Catharina A Passos Mila P Pacheco Valdiana C Surlo Neogelia P de Almeida Jaciane AM Fontes Andrea M Pimentel Raquel Rocha Genoile Oliveira Santana | 2020 | World Journal of Gastroenterology2020，26，44： | 1 |
| 17 | Conditional autoimmunitymediated by human natural anti-FceRIa autoantibodies? 显示文摘 | Michael P Jana M Monique V | 2001 | FASEB J2001，15，12： | 1 |
| 18 | O6-Methylguanine-DNA gene expression and prognosis in breast carcinoma显示文摘 | Cayre C Frederique P Monique D | 2002 | International Journal of Oncology2002，21，5： | 1 |
| 19 | Deficiency of Interstitial cells of cajal in the small intestine of patients with Crohn's Disease显示文摘 | Christophe P Marjolaine B Monique H | 2002 | Am J Gastroenterol2002，97，1： | 1 |
| 20 | Discoidin domain receptor I is a major mediator of inflammation and fibrosis in obstructive nephropathy 显示文摘 | Dominique G Monique K Sandrine P | 2011 | Am J Pathol2011，179，： | 1 |
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