维普中文期刊产品整合服务
214篇 您的检索式:作者名="Moehl"
    题名 作者 年代 出处 被引量
1Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis显示文摘AIM: To study susceptibility genes which may play a potential role in the pathogenesis and etiology of inflammatory bowel disease (IBD). METHODS: To identify potential susceptibility genes we performed global gene expression profiling in patients with IBD and control specimens. For determination of an intrinsic gene expression profile in ulcerative colitis (UC) and Crohn’s disease (CD) compared to normal subjects, mucosal biopsies of non-inflamed regions of the colon and the terminal ileum were subjected to DNA microarray analysis. Real-time RT-PCR and immunohistochemistry were used for verification of selected regulated candidate genes and a genetic analysis was performed. RESULTS: We could show that aquaporin-8 (AQP8) mRNA and protein levels were significantly increased in the colon of UC patients compared to controls. Genetic analysis of the six exons and the promoter region of AQP8, however, revealed no mutations or polymorphisms in IBD patients. CONCLUSION: Our results suggest that upregulation of AQP8 in the colon of UC patients represents a secondary phenomenon which may, due to altered water exchange of the distal intestinal mucosa, disturb the physiologic colonic mucus barrier and thus lead to chronic infla- mmation and ulceration.Alexandra Zahn Christoph Moehle Thomas Langmann Robert Ehehalt Frank Autschbach Wolfgang Stremmel Gerd Schmitz 2007World Journal of Gastroenterology2007,13,11:13
2Shear Strength Model for Lightly Reinforced Concrete Columns显示文摘Halil Sezen Jack P. Moehle 2004Journal of Structural Engineering2004,,11:2
3Effect of Annealing Temperature on Film Morphology of Organic–Inorganic Hybrid Pervoskite Solid‐State Solar Cells显示文摘Amalie Dualeh Nicolas Tétreault Thomas Moehl Peng Gao Mohammad Khaja Nazeeruddin Michael Gr?tzel 2014Adv. Funct. Mater2014,,21:2
4Shear strength model for lightly reinforced concrete columns 显示文摘Halil Sezen and Jack P Moehle 2004ASCE Journal of structural engineering2004,130,11:1
5Exploiting conformationally constrained peptidomimetics and an efficient human compatible delivery system in synthetic vaccine design显示文摘Moreno R Jiang L Moehle K 2001Chem Biol Chem biochem2001,2,11:1
6Genetic inactivation of IL- 1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice显示文摘Alexander MR Moehle CW Johnson JL 2012J Clin Invest2012,122,1:1
7Combinational biominetic chemistry:parallel synthesis of a small library of β-hairpin mimetics Based on loop m from human platelel-derived growth Factor B显示文摘Lu JJ Moehle K Phanapal B 2000Helvetica Chimica Acta2000,83,:1
8Effect of floor slab on behavior of slab-beam-column connection显示文摘French C W Moehle 1991ACI Journal1991,45,5:1
9Effect of annealing temperature on film morphology of organic-inorganic hybrid pervoskite solid-state solar cells显示文摘DUALEH A TETREAULT N MOEHL T 2014Advanced Functional Materials2014,24,21:1
10Factors determining the photovoltaic performance of a CdSe quantum dot sensitized solar cell: the role of the linker molecule and of the counter electrode 显示文摘SERO I M GIMENEZ S THOMAS Moehl 2008Nanotechnology2008,19,42:1
11Light energy conversion by mesoscopic PbS quantum Dots/TiO2 heterojunction solar ceils 显示文摘Lioz Etgar Thomas Moehl Stefanie Gabriel 2012ACS Nano2012,6,4:1
12Cyclopentadithiophene Bridged Donor-Acceptor Dyes Achieve High Power Conversion Efficiencies in Dye-Sensitized Solar Cells Based on the tris-Cobalt Bipyridine Redox Couple显示文摘Hoi Nok Tsao Yi C Y Thomas Moehl 0,,05:1
13Shear Strength Model for Light- ly Reinforced Concrete Columns显示文摘Sezen H Moehle J P 2004Journal of Struc- tural Engineering2004,130,11:1
14An Experimental Study of Slab-column Connection显示文摘AUSTIN D P MOEHLE J P 1992ACI Structural Jourhal1992,89,6:1
15Identification of effect of salbs on flexural behavior of beams 显示文摘Pantazopoulou S J Moehle J P 1990Journal of Engineering Mechanics1990,116,3:1
16Displacement-based design of RC structures subjected to earthquakes显示文摘Moehle J P 1992Earthquake Spectra1992,8,3:1
17Seismic response of beam - col- umn joints in double- deck reinforced concrete bridgeframes 显示文摘MazzoniS Moehle JP 1998ACI Structural Journal1998,98,3:1
18Shear Strength Model for Lightly Reinforced Concrete Columns显示文摘Sezen H Moehle J P 2004ASCE Journal of Structural Engineering2004,130,11:1
19In vitro differentiation of human dental follicle cells with dexamethasone and insulin显示文摘Morsczeck C Moehl C G?tz W 2005Cell Biology International2005,29,7:1
20African aquaculture: Realizing the potential 显示文摘Brummett R E Lazard J Moehl J 2008Food Policy2008,33,5:1
返回顶部 每页显示:
共11页 首页 上一页 第1页 下一页 末页 /11 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费