|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach: Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)显示文摘 | Inzucchi Silvio E Bergenstal Richard M Buse John B Diamant Michaela Ferrannini Ele Nauck Michael Peters Anne L Tsapas Apostolos Wender Richard Matthews David R | 2012 | EN2012，，3： | 6 |
| 2 | Endoscopic findings in patients with Schatzki rings:Evidence for an association with eosinophilic esophagitis显示文摘AIM:To investigate endoscopic findings in patients with Schatzki rings(SRs) with a focus on evidence for eosinophilic esophagitis(EoE).METHODS:We consecutively approached all adult patients scheduled for elective outpatient upper endoscopy for a variety of indications at the German Diagnostic Clinic,Wiesbaden,Germany between July 2007 and July 2010.All patients with endoscopically diagnosed SRs,defined as thin,symmetrical,mucosal structures located at the esophagogastric junction,were prospectively registered.Additional endoscopic findings,clinical information and histopathological findings with a focus on esophageal eosinophilia(≥ 20 eosinophils/high power field) were recorded.The criteria for active EoE were defined as:(1) eosinophilic tissue infiltration ≥ 20 eosinophils/hpf;(2) symptoms of esophageal dysfunction;and(3) exclusion of other causes of esophageal eosinophilia.Gastroesophageal reflux disease was excluded by proton pump inhibitor treatment prior to endoscopy.The presence of ≥ 20 eosinophils/hpf in esophageal biopsies in patients that did not fulfil the criteria of EoE was defined as esophageal hypereosinophilia.RESULTS:A SR was diagnosed in 171(3.3%;128 males,43 females,mean age 66 ± 12.9 years) of the 5163 patients that underwent upper gastrointestinalendoscopy.Twenty of the 116 patients(17%) from whom esophageal biopsies were obtained showed histological hypereosinophilia(≥ 20 eosinophils/hpf).Nine of these patients(8 males,1 female,mean age 49 ± 10 years) did not fulfill all diagnostic criteria of EoE,whereas in 11(9%) patients with ≥ 20 eosinophils/hpf,a definite diagnosis of EoE was made.Three of the 11 patients(27%) with definite EoE had no suspicious endoscopic features of EoE.In contrast,in the 25 patients in whom EoE was suspected by endoscopic features,EoE was only confirmed in 7(28%) patients.Patients with EoE were younger(mean age 41.5 ± 6.5 vs 50.5 ± 11.5 years,P = 0.012),were more likely to have a history of allergies(73% vs 29%,P = 0.007) and complained more often of dysphagia(91% vs 34%,P = 0.004) and food impaction(36% vs 6%,P = 0.007) than patients without EoE.Endoscopically,additional webs were found significantly more often in patients with EoE than in patients without EoE(36% vs 11%,P = 0.04).Furthermore,the SR had a tendency to be narrower in patients with EoE than in those without EoE(36% vs 18%,P = 0.22).The percentage of males(73% vs 72%,P = 1.0) and frequency of heartburn(27% vs 27%,P = 1.0) were not significantly different in both groups.The 9 patients with esophageal hypereosinophilia that did not fulfil the diagnostic criteria of EoE were younger(mean age 49 ± 10 years vs 58 ± 6 years,P = 0.0008) and were more likely to have a history of allergies(78% vs 24%,P = 0.003) than patients with < 20 eosinophils/hpf.Predictors of EoE were younger age,presence of dysphagia or food impaction and a history of allergies.CONCLUSION:A significant proportion of patients with SRs also have EoE,which may not always be suspected according to other endoscopic features. | Michaela Müller Alexander J Eckardt Annette Fisseler-Eckhoff Susanne Haas Ines Gockel Till Wehrmann | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 3 | Is the schatzki ring a unique esophageal entity?显示文摘AIM:To study,whether the association of Schatzki rings with other esophageal disorders support one of the theories about its etiology.METHODS:From 1987 until 2007,all patients with newly diagnosed symptomatic Schatzki rings (SRs) were prospectively registered and followed.All of them underwent structured interviews with regards to clinical symptoms,as well as endoscopic and/or radiographic examinations.Endoscopic and radiographic studies determined the presence of an SR and additional morphological abnormalities.RESULTS:One hundred and sixty-seven patients (125 male,42 female) with a mean age of 57.1±14.6 years were studied.All patients complained of intermittent dysphagia for solid food and 113 (79.6%) patients had a history of food impaction.Patients experienced symptoms for a mean of 4.7±5.2 years before diagnosis.Only in 23.4% of the 64 patients who had endoscopic and/or radiological examinations before their first presentation to our clinic,was the SR previously diagnosed.At presentation,the mean ring diameter was 13.9±4.97 mm.One hundred and sixty-two (97%) patients showed a sliding hiatal hernia.Erosive reflux esophagitis was found in 47 (28.1%) patients.Twenty-six (15.6%) of 167 patients showed single or multiple esophageal webs;five (3.0%) patients exhibited eosinophilic esophagitis;and four (2.4%) had esophageal diverticula.Four (7%) of 57 patients undergoing esophageal manometry had nonspecific esophageal motility disorders.CONCLUSION:Schatzki rings are frequently associated with additional esophageal disorders,which support the assumption of a multifactorial etiology.Despite typical symptoms,SRs might be overlooked. | Michaela Müller Ines Gockel Philip Hedwig Alexander J Eckardt Kathrin Kuhr Jochem Knig Volker F Eckardt | 2011 | World Journal of Gastroenterology2011，17，23： | 2 |
| 4 | Like Phoenix from the Ashes? The Renewal of Clusters in Old Industrial Areas显示文摘 | TODTLING F MICHAELA TRIPPL M | 2004 | Urban Studies2004，41，56： | 1 |
| 5 | Nitrososphaera viennen- sis, an ammonia oxidizing archaeon from soil显示文摘 | Fourna M Michaela S Anja S etal | 2011 | Proceedings of the National Academy of Sciences2011，108，20： | 1 |
| 6 | Nonclinical safety strategies for stem cell therapies显示文摘 | MICHAELA ES DANIEL M ANNAMARIA R | 2012 | Toxicol Appl Pharmacol2012，262，3： | 1 |
| 7 | HIV ‐associated chronic immune activation显示文摘 | Mirko Paiardini Michaela Müller‐Trutwin | 2013 | Immunol Rev2013，，： | 1 |
| 8 | Long - term mobile phone use and acoustic neuroma risk 显示文摘 | David P Tiit M Michaela P | 2014 | Epidemiology2014，25，2： | 1 |
| 9 | Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach: Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)显示文摘 | Inzucchi Silvio E Bergenstal Richard M Buse John B Diamant Michaela Ferrannini Ele Nauck Michael Peters Anne L Tsapas Apostolos Wender Richard Matthews David R | 2012 | EN2012，，3： | 1 |
| 10 | Actions of the antiarrhythmic peptide AAP10 on intercellular coupling显示文摘 | A. Müller Thomas Schaefer Werner Linke Tatjana Tudyka Michaela Gottwald Wolfgang Klaus Stefan Dhein | 1997 | Naunyn - Schmiedeberg’s Archives of Pharmacology1997，，1： | 1 |
| 11 | Relation between the molecular structure and the efficiency of superabsorbent poly- mer (SAP) as concrete admixture to mitigate autogenousshrinkage显示文摘 | Christof S Viktor M Michaela G | 2012 | Cement and Concrete Research2012，，42： | 1 |
| 12 | Highly compatible metal and enzyme catalysts for efficient dynamic ki netic resolution of alcohols at ambient temperature显示文摘 | Belén M M Michaela E Krisztián B | 2004 | Angewandte Chemie International Edition2004，43，47： | 1 |
| 13 | Combined exposure to hydrogen peroxide and lights selectiveeffects on Cyanobacteria, green algae ,and diatoms显示文摘 | Michaela D A Wim A Blahoslav M | 2007 | Environ Sci Technol2007，41，1： | 1 |
| 14 | Identification of a functional protein kinase Cβ promoter polymorphism in humans related to insulin resistance显示文摘 | Martin A. Osterhoff Susanne Heuer Michaela Pfeiffer Jelena Tasic Simone Kaiser Frank Isken Joachim Spranger Martin O. Weickert Matthias M?hlig Andreas F.H. Pfeiffer | 2007 | Molecular Genetics and Metabolism2007，，2： | 1 |
| 15 | Long-term results after video-assisted thoracoscopic surgery for first-time and recurrent spontaneous pneumothorax显示文摘 | Rudolf A Hatz Michaela F Kaps Georgios Meimarakis Florian Loehe Christian Müller Heinrich Fürst | 2000 | The Annals of Thoracic Surgery2000，，1： | 1 |
| 16 | Toxicity of hormonaltherapy显示文摘 | MichaelA LoriRichard M | 1991 | Curr probl cancer1991，36，4： | 1 |
| 17 | Quantitative determination of carotene stereoisomers in carrotjuices and vita2min supplemented (ATBC) drinks 显示文摘 | Michaela M Andreas S Reinhold C | 2000 | Food Chem2000，70，： | 1 |
| 18 | Analysis of Benzopyrene metabolites Formed by Rat Hepatic Microsomes using High Pressure Liquid Chromatography :Optimization of the Method显示文摘 | Michaela M V e ra K Dagmar A | 2009 | Interdisc Toxicol2009，2，4： | 1 |
| 19 | Stressful 'Memories'of plants: Evidence and possible mecha- nisms显示文摘 | BRUCE J A MICHAELA C M JOHNATHAN A N | 2007 | Plant Science2007，173，： | 1 |
| 20 | Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach: Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)显示文摘 | Inzucchi Silvio E Bergenstal Richard M Buse John B Diamant Michaela Ferrannini Ele Nauck Michael Peters Anne L Tsapas Apostolos Wender Richard Matthews David R | 2012 | EN2012，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员