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| 1 | Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: Echinococcosis multilocularis Ulm classification-ultrasound显示文摘AIM: To establish an ultrasonographic classification based on a large sample of patients with confirmed hepatic alveolar echinococcosis(AE).METHODS: Clinical data and ultrasonography(US) findings of 185 patients(100 males; 85 females; mean age at diagnosis: 51.4 ± 17.6 years; mean age at time of US examination: 58.7 ± 18.2 years) were retrospectively reviewed with respect to the US morphology of hepatic AE lesions. The sonomorphological findings were grouped according to a five-part classification scheme.RESULTS: Application of the new classification resulted in the following distribution of sonomorphological patterns among the patients examined: hailstorm(54.1%); pseudocystic(13.5%); ossification(13.0%); hemangioma-like(8.1%); and metastasis-like(6.5%). Only 4.9% of lesions could not be assigned to a sonomorphological pattern.CONCLUSION: The sonomorphological classification proposed in the present study facilitates the diagnosis,interpretation and comparison of hepatic alveolar echinococcosis in routine practice and in the context of scientific studies. | Wolfgang Kratzer Beate Gruener Tanja EM Kaltenbach Sarina Ansari-Bitzenberger Peter Kern Michael Fuchs Richard A Mason Thomas FE Barth Mark M Haenle Andreas Hillenbrand Suemeyra Oeztuerk Tilmann Graeter | 2015 | World Journal of Gastroenterology2015，21，43： | 16 |
| 2 | Serum creatin phosphokinase elevations in patients with Tardive Dyskinesia显示文摘 | Michael FE Anissa AD Darrelll GK | 1993 | Br J Psychiatry1993，162，4： | 1 |
| 3 | Determination of chlorhexidine digluconate and polyhexamethylene biguanide in eye drops by capillary electrophoresis with contactless conductivity detection显示文摘 | Eva M AV Susanne FE Michael AT | 2006 | Analytica Chimica Acta2006，56，561： | 1 |
| 4 | The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function 显示文摘 | Masami K Joseph HC | 2003 | Cell2003，112，25： | 1 |
| 5 | Interleukin-4 inhibits calcium transients in response to carbachol in bovine airway smooth muscle cells 显示文摘 | Madison JM Michael FE | 2001 | American Journal of Respiratory Cell and Molecular Biology2001，25，2： | 1 |
| 6 | 抗氧化剂调节人内皮细胞粘附分子表达显示文摘探讨抗氧化剂能否调节内皮细胞表面的粘附分子表达,以及这种调节是否通过一种NF-κB的活性敏感的机制。方法:内皮细胞表面的粘附分子表达用细胞ELISA方法测定,内皮细胞NF-κB的活性用电泳迁移率分析测定。结果:PDTC和chrysin能明显抑制所有3种粘附分子的表达。DCI可抑制E-selectin和ICAM-1的表达,对VCAM-1没有影响。Probucol仅在低浓度时对ICAM-1有轻微抑制作用,对E-selectin和VCAM-1的表达没有影响。电泳迁移率分析结果,只有PDTC对NF-κB的活性有抑制作用,其它3种抗氧化药无效。结论:抗氧化药抑制内皮细胞粘附分子的表达与它们对核转录因子的作用并无必然的联系。 | 黄虔 Michael Crfe Eckart Fleck | 2000 | 暨南大学学报(自然科学与医学版)2000，21，2： | 1 |
| 7 | Purpura in congenital and acquired rubella显示文摘 | Bayer WL Sherman FE Michaels RH | | 0，，： | 1 |
| 8 | 几种抗氧化剂对细胞间粘附分子-1表达的影响显示文摘目的 探讨抗氧化剂调节内皮细胞表面的粘附分子ICAM-1表达的分子生物学机制。方法 内皮细胞表面的粘附分子表达用细胞ELISA方法测定,内皮细胞NF-kB的活性用电泳迁移率分析测定。结果 PDTC,DCI和chrysin能明显抑制ICAM-1的表达。Probucol仅在低浓度时对ICAM-1有轻微抑制作用。电泳迁移率分析结果,只有PDTC对NF-kB的活性有抑制作用,其它三种抗氧化药无效。结论 这几种抗氧化药抑制内皮细胞表面粘附分子的表达与它们对核转录因子NF-kB的作用并无必然的联系。 | 黄虔 Michael Gife Eckart Fleck | 1999 | 岭南心血管病杂志1999，5，3： | 0 |
| 9 | Effect of Antioxidants on Endothelial Cell Reactive Oxygen Species (ROD Generation and Adhesion of Leukocytes to Endothelial Cells显示文摘Objective To investigatewhether antioxidants inhibit adhesion of leukocytes to endothelium and furthermore, whether all antioxidants regulate NF-KB activation through a redox sensitive mechanism. Methods The effect of the antioxidative substances pyrrolidin dithiocarbamat (PDTC), dichloroisocumarin (DCI), chrysin and probucol on the endothelial leukocyte adhesion were examined under near physiological flow conditions. The antioxidative activity of antioxidants was measured in a DCF fluorescence assay with flow cytometry. The activation of NF-kB in endothelial cells was investigated in a gel shift assay. Results PDTC and probucol did not show an inhibitory effect to the formation of intracellular H2O2 in TNFa activated human vascular endothelial cells (HUVEC) . Chrysin showed a moderate effect. DCI showed a strong antioxidative effect. In contrast, PDTC and chrysin inhibited the adhesion of HL 60 cells to TNFa-stimulated HUVEC. DCI and probucol did not have influence on the adhesion within the area of | 黄虔 Michael Grfe Kristoph Graf Hans Lehmkuhl Eckart Fleck | 2000 | South China Journal of Cardiology2000，1，1： | 0 |
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