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3篇 您的检索式：作者名="Michael A.Morgan"

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		题名	作者	年代	出处	被引量
	1	Shock fragmentation model for gravitational collapse显示文摘A cloud of gas collapsing under gravity will fragment.We present a new theory for this process,in which layers of shocked gas fragment due to their gravitational instability.Our model explains why angular momentum does not inhibit the collapse process.The theory predicts that the fragmentation process produces objects which are significantly smaller than most stars,implying that accretion onto the fragments plays an essential role in determining the initial masses of stars.This prediction is also consistent with the hypothesis that planets can be produced by gravitational collapse.	Michael Wilkinson Bernhard Mehlig Michael A.Morgan	2011	Research in Astronomy and Astrophysics2011，11，5：	2
	2	Prime time for base editing in the mitochondria显示文摘A recent study published in Cell by the Kim lab represents a great advance towards expanding DNA editing possibilities to mitochondrial DNA(mtDNA)as they show reasonable targeted A-to-G conversions in human mtDNA using base editors to broaden the arsenal of available tools.1 Mutations in mitochondrial DNA(mtDNA)are linked to several diseases(Fig.1),thus,development of gene therapy and editing approaches could lead to curative options for patients suffering from these illnesses.In this direction,gene editing tools such as zinc-finger nucleases(mitoZFN),transcription activator-like effector nucleases(mitoTALENs)and meganucleases(mitoARCUS)were shown to eliminate mutant mtDNA and shift heteroplasmy.	Michael A.Morgan Lucas Lange Axel Schambach	2022	Signal Transduction and Targeted Therapy2022，7，8：	0
	3	Targeted cytokine delivery:cell therapy to remodel the pre-metastatic niche显示文摘Tumor metastases present an often difficult to treat therapeutic challenge for cancer patients and their caregivers.The recent paper by the Kaplan group(Kaczanowska et al.)exploited the natural capacity of monocytes or a subset of monocytes to migrate to tumor sites and pre-metastatic niches to deliver IL-12 in a novel anticancer approach designed to stimulate local immune responses.1 This raises the possibility to simultaneously fight cancer on at least two critical fronts,(1)elimination of the primary tumor and(2)inhibition of newly developing pre-metastatic lesions.	Michael A.Morgan Lucas Lange Axel Schambach	2021	Signal Transduction and Targeted Therapy2021，6，8：	0

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