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| 1 | The Isometric Extension of the Into Mapping from the Unit Sphere S_1(E) to S_1(l~∞(Г)) | Xiao Hong FU Department of Mathematics,Jiaying College,Meizhou 514015,P.R.China | 2008 | Acta Mathematica Sinica,English Series2008，24，9： | 6 |
| 2 | 加强卫生院妇幼卫生工作 提高农村住院分娩率显示文摘广东省梅州市强化政府行为,加强对妇幼卫生工作的领导,提高了住院分娩率。实践表明,实现四个转变(卫生院长观念的转变、在家分娩传统观念的转变、接生员职能的转变、工作方法的转变)和做到三个加强(加强卫生院基础设施建设、加强技术人员培训、加强医德医风建设)对提高住院分娩率有重要的作用。 | The Public Health Bureau of Meizhou City,Guangdong Province | 1998 | 中国妇幼保健1998，13，2： | 2 |
| 3 | Extracellular high mobility group box chromosomal protein 1 promotesdrug resistance by increasing the expression of P?glycoprotein expression in gastricadenocarcinoma cells显示文摘 | Yuping Yin Wei Li Meizhou Deng Peng Zhang Qian Shen Guobing Wang Kaixiong Tao | 2014 | Molecular Medicine Reports2014，，4： | 1 |
| 4 | POSITIVE SOLUTIONS TO BOUNDARY VALUE PROBLEM OF FRACTIONAL FUNCTIONAL DIFFERENTIAL EQUATION显示文摘In this paper,we establish sufficient conditions for the existence of positive solutions to a general class of integral boundary value problem(BVP) of nonlinear fractional functional differential equation.A differential operator is taken in the RiemannLiouville sense.Our analysis relies on the Krasnosel'skii fixed-point theorem in cones.We also give examples to illustrate the applicability of our results. | Limei Song School of Math.,Jiaying University,Meizhou 514015,Guangdong | 2012 | Annals of Differential Equations2012，28，3： | 1 |
| 5 | Puerarin protects human umbilical vein endothelial cells against high glucose‐induced apoptosis by upregulating heme oxygenase‐1 and inhibiting calpain activation显示文摘 | Ying‐YingChen JieChen Xin‐MeiZhou Xiang‐HongMeng Jian‐PingJiang Yue‐LiangShen | 2012 | Fundamental & Clinical Pharmacology2012，，3： | 1 |
| 6 | The chemical stability of heavy metals in a natural water system显示文摘A comprehensive investigation of heavy metal pollutants in Xiangjiang river was accomplished to evaluate their chemical stability through three different ways: (1) Chemical speciation by direct measurements; (2) Chemical equilibrium model simulation; (3) Sediment extraction experiments. All the results demonstrated that the directly bioavailable fraction was in a very limited amount. The metal bound to organic ligands, adsorbed particles and precipitated species presented a buffer for solution species. The majority of metals occured in the residues as solid particulates. It was inferred that the heavy metal pollutants in this aquatic system exhibited a high chemical stability. The critical limits of discharging load and pH values were suggested. | Tang Hongxiao, Xue Hanbin, Mao Meizhou, Luan Zhaokun1 Research Center for Eco-Environmental Sciences,Academia Sinica,P,O.Box 934,Beijing 100083,China | 1989 | Journal of Environmental Sciences1989，1，1： | 1 |
| 7 | Comparative study of the effects of anatase and rutile titanium dioxide nanoparticles on the structure and properties of waterborne polyurethane 显示文摘 | Li Kechen Peng Jiangen Zhang Meizhou | 2015 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2015，470，： | 1 |
| 8 | 改善人居环境 提升城市品位显示文摘梅城江南东片人居环境改善工程,是梅州市继东山教育基地、客家公园之后在建设宜居城乡、打造世界客都,推动绿色崛起的又一重大'三旧'改造项目。梅城江南东片改造前地势低洼,污水横流,臭气熏天,建筑杂乱,道路狭窄,安全隐患很大。 | Meizhou Construction Bureau | 2010 | 建筑监督检测与造价2010，，2： | 0 |
| 9 | 攻克铅锌分选难关显示文摘1 小组简介小组名称:铅锌分选 QC 小组小组成立时间:1991年5月小组登记号:91-08小组成员:组长1人,组员12人。成员受 TQC 教育程度:全部参加 TQC电视讲座,经考试取得证书。本循环时间:1996年6月至1997年4月活动课题:攻克铅锌分选难关2 选题理由要把铅、锌从矿石中分选出精矿产品并且技术指标要达到公司和矿下达的要求,即铅精矿含 Pb 40%以上,回收率80%以上,含Zn7%以下,锌精矿含 Zn45%以上。 | Lead-Zinc Separation QC Group,Yushui Sulphur-Copper Mine,Meizhou Jinyan Industrial Group Corporation | 1998 | 南方金属1998，，2： | 0 |
| 10 | Design and experiment analysis of the small maize harvester with attitude adjustment in the hilly and mountainous areas of China显示文摘To solve the problem of small planting plots and large sloping land for mechanized maize harvesting in China hilly and mountainous areas,a small maize harvester with attitude adjustment was designed to realize maize snapping,peeling,straw crushing and attitude adjusting at on time in this study.The basic structure and working principle of the small maize harvester were described,and the key components were designed as follows.The maize snapping device adopted the combination form of maize snapping plates and straw pulling rollers,and the gap of the straw pulling rollers can be adjusted to adapt to different maize varieties.Two pairs of peeling rollers formed a groove arrangement to improve peeling rate and reduced ear grain loss.The pressure feeding device mainly comprised drive chain and three grade pressure feeding rollers to increase the friction between ears and the peeling rollers,and help ears slide.The attitude adjustment advice was designed according to the high point stationary pursuit leveling method.When the attitude angle of the rack approached 0,the small maize harvester reached the level state.The actual range of attitude adjustment was obtained and the accuracy of static attitude adjustment was verified through attitude adjustment test.The influencing factors of ear loss rate and bract peeling rate were determined by orthogonal test,including the rotational speed of straw pulling rollers,peeling rollers and pressure feeding rollers.The mathematical regression model between the experimental factors and indicators was established by using Design Expert,and through the analysis variance to verify the significance of the evaluation indicators,the best combination of operation parameters was determined that the rotational speed of straw pulling rollers,peeling rollers and pressure feeding rollers were 1440 r/min,1535 r/min and 406 r/min.Under the optimal combination of the operation parameters,the ear loss rate and bract peeling rate were 1.33%and 93.98%.The design indicators of the small maize harvester can meet the relevant national standards,and can satisfy the need of maize mechanized harvesting in China hilly and mountainous areas. | Meizhou Chen Guangfei Xu Yuanzhen Wei Yinping Zhang Peisong Diao Huanxiao Pang | 2024 | International Journal of Agricultural and Biological Engineering2024，17，1： | 0 |
| 11 | PERIODIC SOLUTIONS TO A KIND OF RAYLEIGH EQUATION WITH A DEVIATING ARGUMENT AND IMPULSES显示文摘By employing the coincidence degree theory of Mawhin, we study the existence of periodic solutions to a kind of Rayleigh equation with a deviating argument and impulses. Some new results on the existence of periodic solutions to the equation are obtained. | Xingrong Chen Dept. of Math., Jiaying University, Meizhou 514015, Guangdong | 2010 | Annals of Differential Equations2010，26，1： | 0 |
| 12 | DNA origami-based nano-hunter enriches low-abundance point mutations by targeting wild-type gene segments显示文摘Point mutations can be used as biomarkers to perform diagnosis for diseases. In this study, a nanorobot for low-abundance point mutation enrichment was constructed using DNA origami. The novel design achieved limits of detection of 0.1% and 1% for synthesized DNA samples and clinical gene samples, respectively. Resettability was a key property of this method, which also involved a simpler process, lower cost and shorter detection duration than traditional enrichment methods. This novel DNA nanorobot may enable the detection of tumor markers, potentially facilitating early cancer diagnosis. | Longjie Li Kejun Dong Xinyu Wang Meizhou Zhang Jun Li Andreas KNussler Xianjin Xiao Hongbo Wang Yuzhou Wu | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 13 | 医院建筑设计招标的实践与思考显示文摘1概述
创建于1896年,历经百年沧桑的广东省梅州市人民医院(梅州市黄塘医院)以其较强的医务人员队伍、较高的医疗技术水平和良好的医德医风而闻名粤东北、闽西、赣南地区,蜚声海内外,旅外华侨慕名来寻医就诊的亦不在少数,2001年该院年门诊病人已达34万人次,年住院病人数1.8万多人. | People’s Hospital of Meizhou Municipal | 2002 | 现代医院2002，2，4： | 0 |
| 14 | Reduction-responsive nucleic acid nanocarrier-mediated miR-22 inhibition of PI3K/AKT pathway for the treatment of patient-derived tumor xenograft osteosarcoma显示文摘miRNAs are important regulators of gene expression and play key roles in the development of cancer, including osteosarcoma. During the development of osteosarcoma, the expression of miR-22 is significantly downregulated, making miR-22 as a promising therapeutic target against osteosarcoma. To design and fabricate efficient delivery carriers of miR-22 into osteosarcoma cells, a hydroxyl-rich reduction-responsive cationic polymeric nanoparticle, TGIC-CA (TC), was developed in this work, which also enhanced the therapeutic effects of Volasertib on osteosarcoma. TC was prepared by the ring-opening reaction between amino and epoxy groups by one-pot method, which had the good complexing ability with nucleic acids, reduction-responsive degradability and gene transfection performance. TC/miR-22 combined with volasertib could inhibit proliferation, migration and promote apoptosis of osteosarcoma cells in vitro. The anti-tumor mechanisms were revealed as TC/ miR-22 and volasertib could inhibit the PI3K/Akt signaling pathway synergistically. Furthermore, this strategy showed outstanding tumor suppression performance in animal models of orthotopic osteosarcoma, especially in patient-derived chemo-resistant and chemo-intolerant patient-derived xenograft (PDX) models, which reduced the risk of tumor lung metastasis and overcame drug resistance. Therefore, it has great potential for efficient treatment of metastasis and drug resistance of osteosarcoma by the strategy of localized, sustained delivery of miR-22 using the cationic nanocarriers combined with non-traditional chemotherapy drugs. | Dafu Chen Chengyue Lei Weifeng Liu Meiyu Shao Meizhou Sun Jianxun Guo Jingjing Cao Jing-Jun Nie Peng Luo Yuwen Luo Bingran Yu Renxian Wang Shun Duan Fu-Jian Xu | 2023 | Bioactive Materials2023，，10： | 0 |
| 15 | EXISTENCE OF PERIODIC SOLUTION TO HIGHER ORDER DIFFERENTIAL EQUATIONS WITH DEVIATING ARGUMENT显示文摘In this paper,using the coincidence degree theory of Mawhin,we investigate the existence of periodic solutions to higher order differential equations with deviating argument. Some new results on the existence of periodic solutions to the equations are obtained. In addition,we give an example to illustrate the main results. | Lijun Pan (Dept. of Math.,Jiaying University,Meizhou 514015,Guangdong) | 2009 | Annals of Differential Equations2009，25，3： | 0 |
| 16 | Optimization design and experiment on feeding and chopping device of silage maize harvester显示文摘Horizontal feeding devices and plate hob chopping devices are the key component of silage maize harvester.To solve the problem of feeding blockage,reduce energy consumption,and improve the chopping quality of the chopping device a horizontal different diameter five-rollers device(HDDFD)was designed and the plate hob chopping device was simultaneously optimized and analyzed.Through the dynamic analysis,the feeding conveying speed was determined to be 2.0-4.5 m/s.The distance equation of the actual and theoretical cutting-edge curve and the position of the fixed blade were finally obtained.Single factor and response surface orthogonal tests in the bench site were carried out with feeding speed,rotating speed of chopping cylinder,feeding amount,and feeding direction as influencing factors,standard grass length rate(SGLR),and energy consumption per unit mass(ECPUM)as evaluation indexes.The optimal working parameters for chopping performance could be concluded as a feeding speed of 3.39 m/s,rotating speed of the chopping cylinder of 1016.17 r/min,feeding amount of 8.04 kg/s,and feeding direction of 52.2°.In addition,the SGLR and ECPUM were obtained as 95.35%and 37.63 kJ/kg,respectively.The relative error between the experimental results with round parameter combination and the predicted value was verified to be less than 5%.Field tests verified the reliability of the optimized feeding and chopping device.It can be seen that the HDDFD and optimized plate hob chopping device can meet the requirements of mechanized silage harvesting which obviously improves the working quality and reduce the energy consumption of chopping. | Meizhou Chen Guangfei Xu Maojian Wei Xiaowei Li Yuanzhen Wei Peisong Diao Peide Cui Shaomin Teng | 2023 | International Journal of Agricultural and Biological Engineering2023，16，3： | 0 |
| 17 | Shale Lithofacies and Sedimentary Environment of the Third Member,Shahejie Formation,Zhanhua Sag,Eastern China显示文摘Researches into shale lithofacies,their sedimentary environments and relationship benefit understanding both of sedimentary cycle division and unconventional hydrocarbon exploration in lacustrine basins.Based on a 100~300-m-thick dark shale,mudstone and limestone encountered in the lower third member of the Eocene Shahejie Formation(Es3l member)in Zhanhua Sag,Bohai Bay Basin,eastern China,routine core analysis,thin sectioning,scanning electron microscopy(SEM),mineralogical and geochemical measurements were used to understand detailed facies characterization and paleoclimate in the member.This Es3l shale sediment includes three sedimentary cycles(C3,C2 and C1),from bottom to top,with complex sedimentary characters and spatial distribution.In terms of the composition,texture,bedding and thickness,six lithofacies are recognized in this succession.Some geochemical parameters,such as trace elements(Sr/Ba,Na/Al,V/Ni,V/(V+Ni),U/Th),carbon and oxygen isotopes(δ^(18)O,δ^(13)C),and total organic carbon content(TOC)indicate that the shales were deposited in a deep to semi-deep lake,with the water column being salty,stratified,enclosed and reductive.During cycles C3 and C2 of the middle-lower sections,the climate was arid,and the water was salty and stratified.Laminated and laminar mudstone-limestone was deposited with moderate organic matter(average TOC 1.8%)and good reservoir quality(average porosity 6.5%),which can be regarded as favorable reservoir.During the C1 cycle,a large amount of organic matter was input from outside the basin and this led to high productivity with a more humid climate.Massive calcareous mudstone was deposited,and this is characterized by high TOC(average 3.6%)and moderate porosity(average 4%),and provides favorable source rocks. | ZHU Xiaomin ZHANG Meizhou ZHU Shifa DONG Yanlei LI Chao BI Yuequan MA Lichi | 2022 | Acta Geologica Sinica(English Edition)2022，96，3： | 0 |
| 18 | Preparation of P2O5-SiO_(2) hollow microspheres in the presence of phosphoric acid显示文摘Silica hollow microspheres containing phos-phorous have been prepared by a sol-gel/emulsion method which uses tetraethoxysilane(TEOS)as the precursor for the SiO_(2) and phosphoric acid(H3PO4)as the precursor for P2O5.The hollow structure forms an emulsion system which is composed of an oil phase(kerosene,sorbitan monooleate(Span 80))and an aqueous phase(a viscous sol solution of ethanol,TEOS and H3PO4).Some of the phosphorous remains in thefinal silica shell structure even after calcination at 650°C.The hollow structure of the P2O5-SiO_(2)(silicophosphate)was characterized by X-ray diffraction(XRD),polarized optical microscopy(POM),scanning electron microscopy(SEM),nitrogen adsorption measurement and Fourier transform infrared spectroscopy(FTIR). | Wenjiang LI Fei XIE Dongxu HUA Chunli ZHANG Chen DAI Zhenyun YU Meizhou QI Shaojun YU | 2011 | Frontiers of Chemical Science and Engineering2011，5，3： | 0 |
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