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| 1 | Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered. | Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale | 2008 | World Journal of Gastroenterology2008，14，7： | 13 |
| 2 | Molecular mechanisms of salinity tolerance in rice显示文摘Salinity is one of the major abiotic stresses which impose constraints to plant growth and production.Rice(Oryza sativa L.)is one of the most important staple food crops and a model monocot plant.Its production is expanding into regions that are affected by soil salinity,requiring cultivars more tolerant to saline conditions.Understanding the molecular mechanisms of such tolerance could lay a foundation for varietal improvement of salt tolerance in rice.In spite of extensive studies exploring the mechanism of salt tolerance,there has been limited progress in breeding for increased salinity tolerance.In this review,we summarize the information about the major molecular mechanisms underlying salinity tolerance in rice and further discuss the limitations in breeding for salinity tolerance.We show that numerous gene families and interaction networks are involved in the regulation of rice responses to salinity,prompting a need for a comprehensive functional analysis.We also show that most studies are based on whole-plant level analyses with only a few reports focused on tissue-and/or cell-specific gene expression.More details of salt-responsive channel and transporter activities at tissue-and cell-specific level still need to be documented before these traits can be incorporated into elite rice germplasm.Thus,future studies should focus on diversity of available genetic resources and,particular,wild rice relatives,to reincorporate salinity tolerance traits lost during domestication. | Tianxiao Chen Sergey Shabala Yanan Niu Zhong-Hua Chen Lana Shabala Holger Meinke Gayatri Venkataraman Ashwani Pareek Jianlong Xu Meixue Zhou | 2021 | The Crop Journal2021，9，3： | 11 |
| 3 | 轴流风机叶尖泄漏流动的大涡模拟(英文)显示文摘本文采用大涡模拟(LES)的方法研究了在基于外壳直径的雷诺数为9.36×105条件下5叶片的轴流式风扇的流动特性,并且着重分析了叶尖泄漏的流动现象。本文使用了基于有限体积法和分层笛卡尔网格的可压流求解器进行数值计算,并应用了体积守恒的切割网格方法处理风扇几何结构的浸入式边界。同时开发了用于笛卡尔网格的旋转周期性边界条件,这样只需分析由2.5亿网格构造的包含一片叶片的72°区域。该研究首先对网格质量进行了分析,之后讨论了瞬态和时均流场的特性,并与使用RANS的5叶片模拟结果进行了对比。RANS和LES模拟结果的主要不同之处体现在叶尖泄漏涡尾流中的湍流动能。本文进而研究了叶尖间隙对叶尖泄漏涡的影响。研究表明,间隙的大小会影响叶尖泄漏涡的大小形状。此外,间隙中更多的分离现象和反向旋转涡会导致较低的湍流动能。 | Alexej Pogorelov Matthias Meinke Wolfgang Schroder | 2018 | 风机技术2018，60，1： | 2 |
| 4 | Large-eddy simulations and particle-image velocimetry measurements of tundish flow 显示文摘 | Alkishriwi N Meinke M Schroder W | 2006 | Steel Research International2006，77，8： | 1 |
| 5 | Weather,climate,and farmers:an overview 显示文摘 | Stone R C Meinke H | 2006 | Meteorological Applications2006，13，： | 1 |
| 6 | Polygonalization of wheel treads caused by static and dynamic imbalances 显示文摘 | MEINKE P MEINKE S | 1999 | Journal of Sound and Vibration1999，227，5： | 1 |
| 7 | Arabidopsis thaliana:A model plant for genome analysis显示文摘 | Meinke D W | 1998 | Science1998，282，： | 1 |
| 8 | Large eddy simulation显示文摘 | Alkishriwi N Meinke M Schroder W | 2008 | Notes on Numerical Fluid Mechanics and Multidisciplinary Design2008，96，8： | 1 |
| 9 | Glu280 is the nucleophile in the active site of Clostridium thermocellumCelC,a family A endo- 显示文摘 | Wang Q Tull D Meinke A | 1993 | J Biol Chem1993，268，14： | 1 |
| 10 | Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies显示文摘 | GIEFIG C MEINKE A L HANNER M | 2008 | J Exp Med2008，205，： | 1 |
| 11 | Identification of DNA sequences of both genitai and cutaneous HPV types in a small number of keratoacanthomas of nonimmunosuppressed patients显示文摘 | STOCKFLETH E MEINKE B ARNDT R | 1999 | Dermatology1999，198，： | 1 |
| 12 | Weather,climate,and farmers:An overview显示文摘 | Stone R C Meinke H | | 0，，： | 1 |
| 13 | The treatment of scabies with ivermectin显示文摘 | Meinking TL Taplin D Hermida JL | 1995 | N Engl J Med1995，333，1： | 1 |
| 14 | Arabidopsis thaliana:a model plant for genome analysis显示文摘 | Meinke D W Cherry J M Dean C | 1998 | Science1998，282，5389： | 1 |
| 15 | Leafy Cotyledon Mutants of Arabidopsis 显示文摘 | Meinke D W Franzmann L H Nickle T C | 1994 | Plant Cell1994，6，8： | 1 |
| 16 | FPA,a gene involved in floral induction in Arabidopsis ,encodes a protein containing RNA-recognition motif显示文摘 | SCHOMBURG F M PATTON D A MEINKE D W | 2001 | Plant Cell2001，13，： | 1 |
| 17 | The titan mutants of Arabidopsis are disrupted in mitosis and cell cycle control during seed development显示文摘 | Liu C M Meinke D W | 1998 | Plant1998，16，： | 1 |
| 18 | Changing paradigms in parasitic infections: common dermatological helminthic infections and cutaneous myiasis显示文摘 | Meinking TL Burkhart CN Burkhart CG | 2003 | Clin Dermatol2003，21，5： | 1 |
| 19 | Differential equation based constraned reinitialization for level set methods显示文摘 | Daniel Hartmann Matthias Meinke Wolfgang Schroder | 2008 | Journal of Computational Physics2008，227，： | 1 |
| 20 | Arabidopsis thaliana:a model plant for genome analysis显示文摘 | Meinke D W | 1998 | Science1998，282，： | 1 |
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