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| 1 | Validation of conventional non-invasive fibrosis scoring systems in patients with metabolic associated fatty liver disease显示文摘BACKGROUND Non-invasive fibrosis scores are not yet validated in the newly defined metabolic associated fatty liver disease(MAFLD).AIM To evaluate the diagnostic performance of four non-invasive scores including aspartate aminotransferase to platelet ratio index(APRI),fibrosis-4 index(FIB-4),body mass index,aspartate aminotransferase/alanine aminotransferase ratio,diabetes score(BARD),and nonalcoholic fatty liver disease fibrosis score(NFS)in patients with MAFLD.METHODS Consecutive patients with histologically confirmed MAFLD were included.The discrimination ability of different non-invasive scores was compared.RESULTS A total of 417 patients were included;156(37.4%)of them had advanced fibrosis(Metavir≥F3).The area under receiver operating characteristic curve of FIB-4,NFS,APRI,and BARD for predicting advanced fibrosis was 0.736,0.724,0.671,and 0.609,respectively.The area under receiver operating characteristic curve of FIB-4 and NFS was similar(P=0.523),while the difference between FIB-4 and APRI(P=0.001)and FIB-4 and BARD(P<0.001)was statistically significant.The best thresholds of FIB-4,NFS,APRI,and BARD for diagnosis of advanced fibrosis in MAFLD were 1.05,-2.1,0.42,and 2.A subgroup analysis showed that FIB-4,APRI,and NFS performed worse in the pure MAFLD group than in the hepatitis B virus-MAFLD group.CONCLUSION APRI and BARD scores do not perform well in MAFLD.The FIB-4 and NFS could be more useful,but a new threshold is needed.Novel non-invasive scoring systems for fibrosis are required for MAFLD. | Yin-Lian Wu Rahul Kumar Ming-Fang Wang Medha Singh Jiao-Feng Huang Yue-Yong Zhu Su Lin | 2021 | World Journal of Gastroenterology2021，27，34： | 4 |
| 2 | Relation-ships Between Stigma,Social Support,and Depression inHIV-Infected African American Women Living in theRural Southeastern United States显示文摘 | Medha Vyavaharkar Linda Moneyham Sara Corwin Ruth Saunders Lucy Annang Abbas Tavakoli | 2010 | Journal of the As-sociation of Nurses in AIDS Care2010，，2： | 1 |
| 3 | Future of mental health in the metaverse显示文摘The metaverse and non-fungible tokens(NFTs)were some of the hottest tech terms in 2021,according to a Google Trends search.Our review aims to describe the metaverse and NFTs in the context of their potential application in the treatment of mental health disorders.Advancements in technology have been changing human lives at an ever-increasing pace.Metaverse,also known as the threedimensional(3D)internet,is the convergence of virtual reality(VR)and physical reality in a digital space.It could potentially change the internet as we know it,with NFTs as the key building blocks in the new expansive virtual ecosystem.This immersive 3D virtual world boasts the features of the real world with the added ability to change the surrounding environment according to individual needs and requirements.VR,augmented reality(AR)and mixed reality(MR)have been employed as tools in the treatment of various mental health disorders for the past decade.Studies have reported positive results on their effectiveness in the diagnosis and treatment of mental health disorders.VR/AR/MR have been hailed as a solution to the acute shortage of mental health professionals and the lack of access to mental healthcare.But,on the flip side,young adults tend to spend a significant amount of time playing 3D immersive games and using social media,which can lead to insecurity,anxiety,depression,and behavioural addiction.Additionally,endless scrolling through social media platforms negatively affects individuals'attention span as well as aggravating the symptoms of adolescents with attention deficit hyperactivity disorder.We aimed to explore the ramifications of expanding applications of the metaverse on mental health.So far,no other review has explored the future of mental health in the context of the metaverse. | Sadia Suhail Usmani Medha Sharath Meghana Mehendale | 2022 | General Psychiatry2022，35，4： | 1 |
| 4 | Portai hypertension in North Indian children显示文摘 | N. K. Arora R. Lodha S. Gulati A. K. Gupta P. Mathur Medha S. Joshi N. Arora D. K. Mitra | 1998 | The Indian Journal of Pediatrics1998，，： | 1 |
| 5 | Beneficial effect of Annona squamosa extract in streptozotocin-induced diabetic rats 显示文摘 | Kaleem M Medha P Ahmed QU | 2008 | Singapore Medd2008，49，： | 1 |
| 6 | Nanocar tiers for Effective Topical Delivery of Anti lnfectives显示文摘 | Priyanka Prabhu Vandana Patravale Medha Joshi | 2012 | Current Nanoscience2012，8，4： | 1 |
| 7 | Integrated gasification combined cycle : A review of IGCC technology 显示文摘 | Joshi Medha M Lee Sunggyu | 1996 | Energy sources1996，18，5： | 1 |
| 8 | Malignant Peripheral Nerve Sheath Tumor With Primitive Neuroepithelial Differentiation in an Adult:A Case Report显示文摘 | Arti Rameshrao Anvikar Medha Pradeep Kulkarni Nayan Anant Ramteerthakar | 2012 | International journal of surgical pathology2012，20，5： | 1 |
| 9 | Haemodynamic,electrolyte and metabolic changes during percutaneous nephrolithotomy显示文摘 | Medha Mohta Tarun Bhagchandani Asha Tyagi | 2008 | Int Urol Nephro2008，40，2： | 1 |
| 10 | Regulation of mitochondrial protein turnover by thyroid hormone显示文摘 | Medha S Rajwade Surendra S | 1975 | Biochem J1975，152，： | 1 |
| 11 | Cypermethrin-Induced Toxic Effect on Glycogen Metabolism in Estuarine Clam, Marcia Opima (Gmelin, 1791) of Ratnagiri Coast, Maharashtra显示文摘 | Medha Tendulkar Arvind Kulkarni Darakhshan Jabeen Haleem | 2012 | Journal of Toxicology2012，，： | 1 |
| 12 | Comparison of the various lipid ratios and indices for risk assessment in patients of myocardial infarction显示文摘 | Binita G Medha R Baidarbhi C | 2012 | The Canadian Society of Clinical Chemists2012，45，： | 1 |
| 13 | Silicon-mediated genotoxic alterations in Brassica juncea under arsenic stress: A comparative study of biochemical and molecular markers显示文摘Arsenic(As),one of the most harmful toxicant at the global level,severely affects plant metabolism when taken up.Interestingly,the presence of silicon(Si)as a fertilizer in As-contaminated soil is an effective strategy to decrease As accumulation in plants.Brassica juncea(var.Varuna)were grown hydroponically to investigate the role of Si at biochemical and molecular levels under arsenite(As^3+)stress.Seedlings of B.juncea were exposed to As^3+,Si,and a combination of both elements.Our data demonstrated that seedlings exposed to As^3+showed an inhibition in shoot length,chlorophyll,carotenoid,and protein,while co-application of Si improved these growth parameters.Silicon supplementation reduced As accumulation in shoot.Increase/decrease was observed in stress-related parameters(cysteine and proline),antioxidant enzymes(superoxide dismutase,ascorbate peroxidase,and catalase),and oxidative stress markers(malondialdehyde and H2O2),which were improved upon co-application of Si as compared to As^3+alone treatment.Random amplified polymorphic DNA(RAPD)is a suitable biomarker assay for plants for assessing the genotoxicity.Seven RAPD primers produced a total of 39 and 48 bands in the leaves of the untreated and treated seedlings,respectively.The RAPD band-profiles and genomic template stability were consistent with other growth and physiological parameters.In conclusion,the genotoxic alterations along with the biochemical parameters indicate that the exposure to Si mitigates As^3+-induced oxidative stress by improving the stress-related parameters and antioxidant system in B.juncea. | Afsana PRAVEEN Chandana PANDEY Ehasanullah KHAN Medha PANTHRI Meetu GUPTA | 2020 | Pedosphere2020，30，4： | 1 |
| 14 | Observations of Aitken nuclei and trace gases in different environments in India显示文摘 | L. T. Khemani G. A. Momin Medha S. Naik R. Kumar Bh. V. Ramana Murty | 1985 | Water Air and Soil Pollution1985，，2： | 1 |
| 15 | Prospective, Randomized Comparison of Continuous Thoracic Epidural and Thoracic Paravertebral Infusion in Patients With Unilateral Multiple Fractured Ribs—A Pilot Study显示文摘 | Medha Mohta Priyanka Verma Ashok Kr. Saxena Ashok K. Sethi Asha Tyagi Gautam Girotra | 2009 | The Journal of Trauma: Injury Infection and Critical Care2009，，4： | 1 |
| 16 | Parasitic diseases: Liposomes and polymeric nanoparticles versus lipid nanoparticles显示文摘 | Abhijit A. Date Medha D. Joshi Vandana B. Patravale | | Advanced Drug Delivery Reviews0，，： | 1 |
| 17 | Comparative study of ultra- sound-guided continous femoral nerve blockade with continous epidural analgesia for pain relief following total knee replacement 显示文摘 | Harsha S Medha H Vinay K | 2012 | Indian J Anaesth2012，56，3： | 1 |
| 18 | Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning显示文摘 | Kakali Sarkar Zheqing Cai Rigu Gupta Nirmal Parajuli Karen Fox-Talbot Medha S. Darshan Frank J. Gonzalez Gregg L. Semenza | 2012 | Proceedings of the National Academy of Sciences2012，，26： | 1 |
| 19 | Continuous paravertebral infusion of repivacaine with or without fentanyl for pain relief in u- nilateral multiplefractured ribs 显示文摘 | Medha M Ophrii EL Sethi AK | 2013 | Indian J Anaesth2013，57，6： | 1 |
| 20 | Studies of wet deposition and dustfall at pune,India显示文摘 | PILLAI A G MEDHA S N MOMIN G A | 2001 | Water Air and Soil Pollution2001，2001，130： | 1 |
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