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87篇 您的检索式:作者名="Mccarthy JJ"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Ulnar fracture with late radial head dislocation: delayed monteggia fracture显示文摘Stitgen A McCarthy JJ Nemeth BA 2012Orthopedics2012,35,3:1
3Insulin like growth factor- 1- induced phosphorylation and al- tered distribution of tuberous sclerosiscomplex (TSC) 1/TSC2 in C2C12 myotubes显示文摘Miyazaki M McCarthy JJ Esser KA 2010FEBS J2010,277,9:1
4Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin显示文摘McCarthy JJ Li JH Thompson A 0,,07:1
5Illustrating the coupled human - environment system for vulnerability analysis: three case studies 显示文摘Turner BL Matson PA McCarthy JJ 2003Proceedings of the National Academy of Sciences of the United States of America2003,100,14:1
6Synthesis and bio- logical characterisation of sirtuin inhibitors based on the tenovins 显示文摘McCarthy AR Pirrie L Hoilick JJ 2012Bioorg Med Chem2012,20,5:1
7Aspirin resistance and a single gene显示文摘Jefferson BK Foster JH Mccarthy JJ 0,,15:1
8Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patients 显示文摘McCarthy JJ Meyer J Molitcrno D J 2003Hum Genet2003,114,1:1
9Unilateral postoperative chest wall radiotherapy in bilateral tissue expander/implant re- construction patients : a prospective outcomes analysis 显示文摘McCarthy CM Pusic AL Disa JJ 2005Plast Reconstr Surg2005,116,6:1
10Personalized medicine: revolutionizing drug discovery and patient care显示文摘Ginsburg GS McCarthy JJ 2001Trends Biotechnol2001,19,12:1
11Large scale association analysis for identification of genes underlying premature coronary heart disease= cumulative perspective from analysis of 111 candidate genes显示文摘McCarthy JJ Parker A Salem R 2004J Med Genet2004,41,5:1
12Excess dietary salt alters angiotensinergic regulation ofneurons in the rostral ventrolateral medulla显示文摘Adams JM McCarthy JJ Stocker SD 2008Hypertension2008,52,5:1
13Aspirin resistance and a single gene显示文摘Jefferson BK Foster JH McCarthy JJ 2005Am J Cardiol2005,95,:1
14Aspirin resistance and asingle gene显示文摘Jefferson BK Foster JH Mccarthy JJ 2005Am J Cardiol2005,95,6:1
15Aspirin resistance and a single gene显示文摘Jefferson BK Foster JH McCarthy JJ 2005Am J Cardiol2005,95,6:1
16Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes显示文摘McCarthy JJ Parker A Salem R 2004J Med Genet2004,41,5:1
17The MyomiR network in skeletal muscle plasticity显示文摘McCarthy JJ 0,,03:1
18Ulnar fracture withlate radial head dislocation : delayed Monteggia fracture 显示文摘Stitgen A McCarthy JJ Nemeth BA 2012Or-thopedics2012,35,3:1
19Large scale association analysis for identification of genes underlying premature coronary heart disease : cumulative perspective from analysis of 111 candidate genes显示文摘McCarthy JJ Parker A Salem R 2004J Med Genet2004,41,5:1
20Iatrogenic radial nerve injury with cannulated fixation of medial epicondyle fractures in the pediatric humerus:a report of 2 cases显示文摘Marcu DM Balts J McCarthy JJ 2011J Pediatr Orthop2011,31,2:1
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